Zachariassenvester7119

Gold nano-particles were coated with the spike protein (S protein) of SARS-CoV-2 and exposed to increasingly acidic conditions. Tiplaxtinin inhibitor Their responses were investigated by monitoring the surface plasmon resonance (SPR) band shift. As the external pH was gradually changed from neutral pH to pH ∼2 the peak of the SPR band showed a significant red-shift, with a sigmoidal feature implying the formation of the gold-protein aggregates. The coating of S protein changed the surface property of the gold enough to extract the coverage fraction of protein over nano particles, Θ, which did not exhibit clear nano-size dependence. The geometrical simulation to explain Θ showed the average axial length to be a = 7. 25 nm and b =8.00 nm when the S-protein was hypothesized as a prolate shape with spiking-out orientation. As the pH value externally hopped between pH∼3 and pH∼10, a behavior of reversible protein folding was observed for particles with diameters >30 nm. It was concluded that S protein adsorption conformation was impacted by the size (diameter, d) of a core nano-gold, where head-to-head dimerized S protein was estimated for d ≤ 80 nm and a parallel in opposite directions formation for d = 100 nm.New coronavirus (COVID-19) is a newly emerging and highly infectious form of typical pneumonia with a high rate of transmission. The COVID-19 pneumonia has spread to 147 countries and areas as of Mar.16th 2020, which has tremendous impact on the global public health. It is well known that, in China, the pandemic has been contained effectively with a series of emergency measures. It is necessary to share the existing experience of China in the fight against the pandemic to the world. Especially, during the process of prevention and containment of the pandemic, ambulances play an important role in transporting infectious patients. In this paper, focusing on the safety and quantity of negative pressure ambulances, the influence of ambulance on newly confirmed cases is given. Analysis of negative pressure ambulance on the containment of COVID-19 is shown. The potential development of ambulance is discussed. While the pandemic still continues spreading across the world, we hope to share our experience in the implementation of these strategies by China to save more life.

In 2020, human society underwent several drastic changes due to the coronavirus disease 2019 (COVID-19) pandemic, which generated an unprecedented global impact. Since the onset of the COVID-19 pandemic, various pressing concerns underlying food security, such as transport, production, and maintenance of the supply chain, have been raised.

The present study aimed to describe and review the merits of entomophagy in the post COVID-19 world, especially with regard to the low risk for zoonotic disease spread, high production rate, and future prospects for inducing entomophagy to enhance the diversity in the food system in comparison to conventional livestock.

The advantages of entomophagy in the post COVID-19 world have been elucidated herein, with particular emphasis on the minimal risk of zoonotic disease transmission and production efficiency, in addition to the future goal of establishment of entomophagy to expand redundancy and diversity in the food system as against the utility of conventional livestock. In the current scenario, as well as in the post COVID-19 situation, boosting entomophagy may play a pivotal role in global food security, as the aspects already touched upon have amply demonstrated.

The advantages of entomophagy in the post COVID-19 world have been elucidated herein, with particular emphasis on the minimal risk of zoonotic disease transmission and production efficiency, in addition to the future goal of establishment of entomophagy to expand redundancy and diversity in the food system as against the utility of conventional livestock. In the current scenario, as well as in the post COVID-19 situation, boosting entomophagy may play a pivotal role in global food security, as the aspects already touched upon have amply demonstrated.Social impacts and serious damages caused by the COVID-19 pandemic have resulted in public introspection on the issue of ecological environmental protection. However, whether the public cognition of COVID-19 can promote pro-environmental behavioral intentions (PEBI) has not yet been determined; this is crucial for studying the ecological significance of the pandemic. Based on the affective events theory (AET), this study investigated the mechanism by which COVID-19 emergency cognition influences public PEBI. Following an analysis of 873 public questionnaires, the results reveal that public cognition of COVID-19 emergency can significantly promote PEBI. Among them, the effect of emergency coping is stronger than that of emergency relevance. Besides, the positive and negative environmental affective reactions aroused by COVID-19 pandemic play a mediating role between the emergency cognition and PEBI. Moreover, the positive environmental affective reactions show a stronger positive effect on household-sphere PEBI. However, the negative environmental affective reactions are more prominent in promoting public-sphere PEBI. This research aims to bridge a research gap by establishing a link between COVID-19 pandemic and PEBI. The findings can provide useful recommendations for policymakers to find the opportunity behind the COVID-19 emergency to promote public PEBI.This study assessed change in self-reported Big Five personality traits. We conducted a coordinated integrative data analysis using data from 16 longitudinal samples, comprising a total sample of over 60 000 participants. We coordinated models across multiple datasets and fit identical multi-level growth models to assess and compare the extent of trait change over time. Quadratic change was assessed in a subset of samples with four or more measurement occasions. Across studies, the linear trajectory models revealed declines in conscientiousness, extraversion, and openness. Non-linear models suggested late-life increases in neuroticism. Meta-analytic summaries indicated that the fixed effects of personality change are somewhat heterogeneous and that the variability in trait change is partially explained by sample age, country of origin, and personality measurement method. We also found mixed evidence for predictors of change, specifically for sex and baseline age. This study demonstrates the importance of coordinated conceptual replications for accelerating the accumulation of robust and reliable findings in the lifespan developmental psychological sciences.Cybersecurity is an ever-present problem for organizations, but organizational science has barely begun to enter the arena of cybersecurity research. As a result, the "human factor" in cybersecurity research is much less studied than its technological counterpart. The current manuscript serves as an introduction and invitation to cybersecurity research by organizational scientists. We define cybersecurity, provide definitions of key cybersecurity constructs relevant to employee behavior, illuminate the unique opportunities available to organizational scientists in the cybersecurity arena (e.g., publication venues that reach new audiences, novel sources of external funding), and provide overall conceptual frameworks of the antecedents of employees' cybersecurity behavior. In so doing, we emphasize both end-users of cybersecurity in organizations and employees focused specifically on cybersecurity work. We provide an expansive agenda for future organizational science research on cybersecurity-and we describe the benefits such research can provide not only to cybersecurity but also to basic research in organizational science itself. We end by providing a list of potential objections to the proposed research along with our responses to these objections. It is our hope that the current manuscript will catalyze research at the interface of organizational science and cybersecurity.Large-scale and diffuse population flow amplifies the localized COVID-19 outbreak into a widespread pandemic. Network analysis provides a new methodology to uncover the topology and evolution of the population flow and understand its influence on the early dynamics of COVID-19 transmission. In this paper, we simulated 42 transmission scenarios to show the distribution of the COVID-19 outbreak across China. We predicted some original (Guangzhou, Shanghai, Shenzhen) had higher total aggregate population outflows than Wuhan, indicating larger spread scopes and faster growth rates of COVID-19 outbreak. We built an importation risk model to identify some major cities (Dongguan and Foshan) with the highest total importation risk values and the highest standard deviations, indicating the core transmission chains (Dongguan-Shenzhen, Foshan-Guangzhou). We built the population flow networks to analyze their Spatio-temporal characteristics and identify the influential sub-groups and spreaders. By removing different influential spreaders, we identified Guangzhou can most influence the network's topological characteristics, and some major cities' degree centrality was significantly decreased. Our findings quantified the effectiveness of travel restrictions on delaying the epidemic growth and limiting the spread scope of COVID-19 in China, which helped better derive the geographical COVID-19 transmission related to population flow networks' structural features.Convalescent plasma has emerged as a promising therapeutic agent for patients with coronavirus disease 2019 (COVID-19), has received emergency use authorization, and is being widely used during the COVID-19 pandemic. Passive antibody therapy via plasma or serum has been successfully used to treat infectious diseases for more than a century. Passive antibody administration is based on the presumption that convalescent plasma or serum contains therapeutic antibodies that can be passively transferred to the plasma recipient. There are numerous examples in which convalescent plasma has been used successfully as post-exposure prophylaxis and treatment of infectious diseases, including previous coronavirus outbreaks. In the context of the COVID-19 pandemic, convalescent plasma was demonstrated to be safe and potentially effective among patients infected with COVID-19. This review provides an overview of the historical uses of convalescent plasma therapy, summarizes current evidence for convalescent plasma use for COVID-19, and highlights future antibody therapies.Outbreaks of COVID-19 (coronavirus disease 2019) have been reported in workers in fish farms and fish processing plants arising from person-to-person transmission, raising concerns about aquatic animal food products' safety. A better understanding of such incidents is important for the aquaculture industry's sustainability, particularly with the global trade in fresh and frozen aquatic animal food products where contaminating virus could survive for some time. Despite a plethora of COVID-19-related scientific publications, there is a lack of reports on the risk of contact with aquatic food animal species or their products. This review aimed to examine the potential for Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) contamination and the potential transmission via aquatic food animals or their products and wastewater effluents. The extracellular viability of SARS-CoV-2 and how the virus is spread are reviewed, supporting the understanding that contaminated cold-chain food sources may introduce SAR-CoV-2 via food imports although the virus is unlikely to infect humans through consumption of aquatic food animals or their products or drinking water; i.