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1-18.5°). The lowest splay values were in the sports car seat (8.96°) and truck seat (7.46°). This reduction in splay was attributed to the more aggressive bolsters in the sports car and a higher seat design position in the pickup truck seat. Following participant splay the pressures in the seat bolsters increased while the pressure in the left thigh and left buttocks regions decreased. By determining the comfortable ranges of splay and how pressure distribution is affected, seat designers and automobile manufacturers can use these data when evaluating seat designs and occupant positioning. Workers in hospitals, clinics, and contract research organizations who repetitively use syringes have an increased risk for musculoskeletal disorders. This study developed and tested a novel syringe adapter designed to reduce muscle strain associated with repetitive fluid draws. Three syringe plunger extension methods (ring-finger, middle-finger, and syringe adapter) were studied across twenty participants. Electromyogram signals for the flexor digitorum superficialis and extensor digitorum muscles were recorded. The syringe adapter required 31% of the 90th percentile flexor muscle activity as compared to the ring-finger syringe extension method, and 45% the 90th percentile flexor muscle activity as compared to the middle-finger method (p less then 0.001). The greatest differences were observed when the syringe was near full extension. Although the syringe adapter took more time than the other syringe extension methods (1.5 times greater), it greatly helped reduce physical stress associated with repetitive, awkward syringe procedures. INTRODUCTION The period following discharge can present risks for older adults. Most research has focused on hospital discharge with less attention paid to on-going care needs. Despite evidence that patients undertake 'invisible work' to improve care safety, their reported willingness to be involved in care, and the consensus that successful transitions interventions include patient involvement, in reality, this is variable. Further, little research has viewed transitional care as a 'system', with gaps, interdependencies and variability across settings, nor the role of patients and families in supporting the system resilience. RESEARCH OBJECTIVES 1) model transitional care from multiple perspectives using the Functional Resonance Analysis Method (FRAM); 2) use the model to develop a theory of change to support intervention development. METHOD We drew data from two studies i) exploring the perspective of older adults across transitional care, and ii) exploring how health services experience transitional care. We employed the FRAM to develop a model of transitional care, with a system boundary spanning an older patient's admission to hospital, through to thirty days post-discharge. FINDINGS Modelling transitional care from multiple perspectives was challenging. 27 functions were identified with interdependencies between hospital-based functions and patient-led functions once home, the success of which may impact on transitions 'outcomes' (e.g. safety events, readmissions). The model supported development of a theory of change, to guide future intervention development. CONCLUSIONS Supporting certain patient-facing upstream hospital functions (e.g. Apitolisib encouraging mobility, supporting a better understanding of medication and condition), may lead to improved outcomes for patients following hospital discharge. Hospital-based care of pediatric trauma patients includes transitions between units that are critical for quality of care and patient safety. Using a macroergonomics approach, we identify work system barriers and facilitators in care transitions. We interviewed eighteen healthcare professionals involved in transitions from emergency department (ED) to operating room (OR), OR to pediatric intensive care unit (PICU) and ED to PICU. We applied the Systems Engineering Initiative for Patient Safety (SEIPS) process modeling method and identified nine dimensions of barriers and facilitators - anticipation, ED decision making, interacting with family, physical environment, role ambiguity, staffing/resources, team cognition, technology and characteristic of trauma care. For example, handoffs involving all healthcare professionals in the OR to PICU transition created a shared understanding of the patient, but sometimes included distractions. Understanding barriers and facilitators can guide future improvements, e.g., designing a team display to support team cognition of healthcare professionals in the care transitions. Determining ways to facilitate participation of persons with a physical disability is crucial and clothing may play a central role. This review aims to synthesize and examine the role of clothing on participation of persons with a physical disability. Six research databases and grey literature were searched following Arksey & O'Malley's six steps, including multiple expert consultations. English and French articles contributing to how clothing affects participation were included and tabulated based on the International Classification of Functioning, Disability and Health. Fifty-seven articles and 88 websites were included. A variety of stakeholder perspectives, diagnoses, and types of clothing were represented. Clothing mostly influences mobility and self-care, as well as various personal factors. Forty-nine percent of articles reported essential clothing design features to consider. Clothing is an important and complex environmental factor that interacts with all health domains, including participation. Future research should consider intersectoral initiatives. The purpose of this study was to assess postural stability in the medial-lateral (ML) direction when carrying unilateral and bilateral loads during stair negotiation. Twenty-four healthy young adults were instructed to ascend and descend a three step staircase under three load conditions no load, 20% body mass (BM) bilateral load, and 20% BM unilateral load. A modified time-to-contact (TTC) method was proposed to evaluate postural stability during stair negotiation. Carrying unilateral loads required more rapid postural adjustments as evidenced by lower minimum ML TTC and ML TTC percentage as compared bilateral loads and no load during stair descent. In addition, lower ML TTC and TTC percentage were found for loaded limb stance for stair descent. Taken together, unilateral loads and the loaded leg during stair descent are of concern when considering postural stability during load carriage. These results illustrate differing postural control challenges for stair ascent and descent during load carriage.