Wureese9136

nancy, due to late diagnostic and hospitalisation, that led to urgent laparotomy operations rather than conservative treatment.OBJECTIVE The aim The aim of our study was to determine the effect of CBT in patients with uncontrolled BA against the background of excess body weight and obesity. PATIENTS AND METHODS Materials and methods By the study design there were examined 78 patients who had a primary diagnosis of uncontrolled BA. RESULTS Results The patients in the main group had significant positive dynamics regarding a number of AQLQ questionnaires, namely emotions, activity, overall quality of life (p≤0.05). These patients also had a positive dynamics in overcoming anxiety-depressive disorders, namely from 10.23 ± 0.81 points anxiety disorders scored 7.65 ± 0.98 points after CBT, and depressive changes - from 10.01 ± 0.79 points to 7.69 ± 0.67 points by the HADS scale (p ≤0.05). CONCLUSION Conclusions The use of CBT has a positive effect on certain indices of the AQLQ questionnaire (p≤0.05) and has a positive effect on the psychological state of the patient, namely, it reduces the manifestations of anxiety and depression (p≤0.05) in patients with uncontrolled asthma as well as improves the course of uncontrolled asthma by a number of indices, namely reducing the frequency of use of short-acting β-2-agonists, nocturnal symptoms of asthma, the amount of oral and peroral steroids.OBJECTIVE The aim To determine the dynamics of changes in metric parameters of the duct system of rat submandibular glands in normal conditions and chronic ethanol intoxication. PATIENTS AND METHODS Materials and methods 50 albino outbred rats were involved in the experiment. 10 animals were assigned in the control group, 40 animals - in the experimental group. Animals were sacrificed on 5, 9, 12 and 30 days by overdose of thiopental anesthesia. Pieces of the submandibular glands were embedded into epon-812 according to the conventional technique. RESULTS Results On day 5 of the experiment the lumen diameter of intercalated duct reduced by 9,15 % (р less then 0,05). GLXC-25878 purchase The lumen diameter of the striated ducts was by 5,29 % significantly greater than the values in controls (р less then 0,05). The lumen diameter of the granular ducts reduced by 2,45 % (р less then 0,05). On day 30 of the experiment the height of the epithelial cells of the intercalated ducts was by 8,47 % significantly less (р less then 0,05), the height of the epithelial cells of the striated ducts was by 12,27 % less (р less then 0,05) and the height of the epithelial cells of the granular ducts was by 11,96 % less (р less then 0,05) than the values in controls. CONCLUSION Conclusions No recovery of parameters occurs by day 30 of the experiment, indicating the depletion of the secretory epithelium of the duct system, due to dystrophic changes caused by vascular disorder in the microvasculature.OBJECTIVE The aim To evaluate the levels of plasminogen activator type 1 inhibitor, asymmetric dimethylarginine and endothelial nitric oxide synthase on day 10-14 in patients, depending on the presence or absence of concomitant type 2 diabetes and the type of reperfusion therapy. PATIENTS AND METHODS Materials and methods The study involved 130 patients with acute myocardial infarction, divided into 2 groups Group 1 consisted of patients with acute myocardial infarction with type 2 diabetes mellitus (n = 73), Group 2 comprised patients with acute type 2 diabetes mellitus (n = 57). The quantitative content of IAP-1 was determined by enzymelinked immunosorbent assay using a commercial test system manufactured by Technoclone PAI-1 ELISA Kit (Austria), NOS - Enzyme-Linked Immunosorbent Assay (ELISA) Kit for Nitric Oxide Synthase Endothelial (NOS) ADMA ELISA Kit (Austria). RESULTS Results and conclusions Percutaneous coronary intervention contributes to a significant reduction in the content of ADMA, which is a marker of endothelial dysfunction and increase NOS on the 10-14th day of acute myocardial infarction compared with standard therapy. During PCI, the level of IAP-1 did not significantly change in the time course of treatment due to post-inflammatory and post-traumatic activation of platelets in the vascular wall.OBJECTIVE The aim of the study was to investigate the prevalence of generalized periodontitis depending on age and biotype of periodontium. PATIENTS AND METHODS Materials and methods We examined 855 males aged 20-55 years, who were divided into 2 groups the main group - 570 surveyed with a generalized periodontitis, the comparison group - 285 dental healthy individuals.The diagnosis of generalized periodontitis was established by the classification Danilevsky M.F. (1994) and refined by using paraclinical indices. The periodontal biotype was determined using Hu-Friedy Colourvue Biotype Probe. RESULTS Results As a result of the conducted researches was establish, in the carriers of blood group O (I) and A (II), developed forms of generalized periodontitis were found, on average, 2.7 times more often than the initial forms of the disease. Instead, at the representatives of B (III) and AB (IV) groups blood the frequency of initial GP - I degree was on average, 1.2 times greater than the prevalence of developed forms of generalized periodontitis. Also as a result of our researches, we found that the cluster A1 had 39.30% patients, cluster A2 was found at 28, 77%, and cluster B - 31.93% of the total number of patients with generalized periodontitis. CONCLUSION Conclusions As a result of our research, it was found that in the carriers of the blood group O (I) and A (II), more advanced forms of generalized periodontitis were observed, which was confirmed by the presence of the biotype of the periodontal disease in the cluster A1 and A2.OBJECTIVE The aim The paper is aimed at creation of a procedure for determining the loss of any body organ or its functions, genital mutilation, as the signs of grievous bodily harm, penalty for which is stipulated by the Article 121 of the Criminal Code of Ukraine, as well as establishing the possibilities of legal setting of the concept of "genital mutilation". PATIENTS AND METHODS Materials and methods Over 100 criminal proceedings, involving forensic medical examination, under the Article 121 of the Criminal Code of Ukraine for the period from 2007 to 19.05.2019 have been studied. Common methods of research have been used, namely, the analysis and synthesis, statistical method, as well as own observations of the process of judicial examination of the above criminal proceedings, as well as individual interviews, survey of the victims and their family members in total of 39 people. RESULTS Results and conclusions The findings of the investigation enabled detecting the gaps in the regulation of the procedure to define genital mutilation as a characteristic feature of grievous bodily harm.