Wrennamstrup2871
case reports; immunoglobulins; neutropenia; thrombocytopenia.
case reports; immunoglobulins; neutropenia; thrombocytopenia.
Magnetic resonance imaging is the standard imaging modality for detecting disc pathology due to its advantage of lack of radiation, multiplanar imaging capability, excellent spinal soft-tissue contrast, and precise localization of intervertebral discs changes. The aim of the study is to find out the prevalence of lumbar disc degenerative disorder among patients undergoing magnetic resonance imaging in a tertiary care hospital.
A descriptive cross-sectional study was conducted in the Department of Radiodiagnosis and Interventional Radiology of a tertiary care centre among patients with complaints of low back pain from 24th May, 2021 to 31st December, 2021 in a tertiary care hospital. Ethical clearance was taken from the Institutional Review Committee (Reference number 134/2077-78). A sample size of 899 was taken and convenience sampling was done. Collected data were entered and analyzed on Statistical Package for the Social Sciences version 22.0. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage for binary data and mean with standard deviation for continuous data.
Among 899 patients undergoing magnetic resonance imaging, the prevalence of lumbar disc degenerative disorder was found to be 155 (17.24%) (14.77-19.70 at 95% Confidence Interval).
The prevalence of lumbar disc degenerative disorder among patients undergoing magnetic resonance in our study was lower when compared to other similar studies conducted in similar settings.
disc degeneration; low back pain; magnetic resonance imaging.
disc degeneration; low back pain; magnetic resonance imaging.
Chickenpox is an acute, highly infectious disease. Outbreaks can occur in adults in closed institutional settings like hostels and barracks. This study aims to report varicella zoster outbreak among male military personnel in a military training centre.
An outbreak investigation of chickenpox in a military training school and tertiary hospital was conducted. Ethical approval was taken from the Institutional Review Committee (Reference number 267). Data was collected from February 5, 2020 to April 10, 2020 by questionnaire and clinical examination. Case definitions were prepared as per the Centre for Disease Control and Prevention criteria. Data was entered and analysed in Microsoft Excel 2010.
Out of the 167 male personnel in the training centre, 90 (53.89%) were susceptible to varicella and 84 (50.29%) were close contacts. The secondary attack rate of varicella zoster was 21.43% (18 cases). The mean age of the patients was 22.33±1.72 years. The mean days of admission were 5±2.28 days. The most common clinical features were generalised rash in 18 (100%), fever in 15 (83.33%), and body ache in 12 (66.67%) cases.
Natural history, clinical, and epidemiological features of varicella zoster in a closed institutional setting was studied with the secondary attack rate being less as compared to other studies.
chickenpox; military; outbreak.
chickenpox; military; outbreak.
Organophosphorus is an easily available compound, especially in agriculture and farming related areas. This study evaluated organophosphorus poisoning among the population in those high-risk areas. The main objective of this study is to find out the prevalence of organophosphorus poisoning among acute poisoning cases presenting to the Emergency Department of a secondary care centre.
A descriptive cross-sectional study was conducted among 427 patients presenting to the Emergency Department in a secondary care centre from 17th July, 2018 to 14th January, 2022. Ethical clearance was taken from the Institutional Review Committee (Reference number 01/2075-76). All the patients presenting to the Emergency Department were included and the patients without consent, patients with trauma, accident, severe illness and other emergency conditions were excluded. A convenience sampling was done. Data were collected and entered in Microsoft Excel version 2007 and analyzed using Statistical Package for the Social Science version 25.0. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage for binary data.
Out of 427 patients, 203 (47.54%) (42.80-52.28 at 95% Confidence Interval) had organophosphorus poisoning. It was most commonly seen in the age group 16-30 years among 103 (50.74%).
The prevalence of organophosphorus poisoning in our study was similar when compared to other studies conducted in similar settings. Most of the organophosphorus poisoning cases were intentional and suicidal which is similar to other studies.
acetaminophen; emergency departments; organophosphorus poisoning; prevalence.
acetaminophen; emergency departments; organophosphorus poisoning; prevalence.
People from rural areas of Nepal struggle to have access to adequate medical care on time. Most of the tertiary centres are overburdened by patients, while the peripheral health facilities have been unable to function efficiently due to a lack of infrastructures and skilled manpower needed to run hospitals smoothly. We present a case of a 21-year-old primigravida at 41 weeks and 3 days of gestation with mild COVID-19 symptoms who underwent a Caesarean section for non-progression of labour and foetal distress at a primary health care centre in Nepal; however, both maternal and foetal outcomes were favourable. Therefore, upgrading the quality of care in peripheral health facilities can help in the achievement of accessibility, equity, and quality in health care service in Nepal.
caesarean section; COVID-19; health equity; Nepal; primary health care.
caesarean section; COVID-19; health equity; Nepal; primary health care.
Vitamin D deficiency is a global health concern with over billions of people worldwide being vitamin D deficient or insufficient. Many epidemiological studies have reported cardiovascular diseases, autoimmune diseases and neoplastic diseases to be associated with vitamin D levels. This study aims to find out the prevalence of vitamin D deficiency in patients presenting to the outpatient Department of Medicine of a tertiary care center.
This was a descriptive cross-sectional study done among 362 patients in the outpatient Department of Medicine of a tertiary care center between May, 2016 and August, 2016. Ethical Approval was taken from Institutional Review Committee (Reference number 21082015). Convenience sampling was done. Informed consent was obtained and data were collected. Data were analysed using the Statistical Package for the Social Science version 25.0. Point estimate at a 95% Confidence Interval was calculated along with frequency and percentages for binary data.
Out of 362 patients, vitamin D deficiency was found in 215 (59.39%) (54.33-64.45 at 95% Confidence Interval) patients.
The prevalence of vitamin D deficiency was found to be lower to the other studies done in in similar settings. Physicians should be aware of the growing prevalence of vitamin D deficiency.
avitaminosis; prevalence; vitamin deficiency.
avitaminosis; prevalence; vitamin deficiency.
Valvular heart disease continues to cause significant morbidity and mortality around the world, with rheumatic heart disease accounting for the bulk of cases in developing nations. The aim of this study is to find out the prevalence of rheumatic heart disease among patients with valvular heart disease admitted to the in-patient department of a tertiary care centre.
A descriptive cross-sectional study was conducted from December, 2018 to December, 2020 at a tertiary care centre after receiving ethical approval from the Institutional Review [Reference number 395 (6-11) e2 077/078]. Patients of age ≥18 years presenting with valvular manifestations of any disease diagnosed by transthoracic echocardiography were included and patients other than Nepalese nationals were excluded. Convenience sampling was done and a sample size of 327 was taken. Data were collected, entered and analyzed using the Statistical Package for the Social Sciences version 22.0. Point estimate at a 95% Confidence Interval was calculated along with frequency and percentages for binary data.
Among 327 patients, the prevalence of rheumatic heart disease was found to be 237 (72.47%) (67.63-77.31 at 95% Confidence Interval).
The prevalence of rheumatic heart disease was similar to the other similar studies conducted in similar settings.
epidemiology; prevalence; rheumatic heart disease.
epidemiology; prevalence; rheumatic heart disease.
The complete absence of limbs is a rare occurrence. Though the causes are various, it is hard to elicit most of the time. They are usually diagnosed via anomaly scan but the lack of access to the same can often lead to a term presentation. It is still not uncommon to receive pregnant patients at term to the hospital or in labour as the first antenatal visit. Increasing the feasibility of the scan can help in the early diagnosis and management. Here, we report a rare combination of limb defects that we managed in a district-level hospital and highlight the difficulties in the management and referral of the patients while working in rural areas.
amelia; antenatal care; congenital limb deformities; fetal ultrasonography.
amelia; antenatal care; congenital limb deformities; fetal ultrasonography.
Despite oral cancer being a common cancer in Nepal, little is known about oral potentially malignant disorders which have a high likelihood of malignant transformation. This study aims to find out the prevalence of oral potentially malignant disorders among patients attending the Department of Oral Medicine and Radiology of a tertiary care dental hospital.
A descriptive cross-sectional study was carried out among 611 patients from 14th January, 2021 to 15th July, 2021 at the Department of Oral Medicine and Radiology of a tertiary care centre after receiving ethical clearance from the Institutional Review Committee (Reference number 2306202002). CX5461 Convenience sampling was done. Patients aged 18 years and above were enrolled into the study. Follow-up cases and patients requiring emergency treatment were, however, excluded. All demographic data, cancer and dietary history and clinical examinations were recorded. Descriptive analysis was done using Statistical Package for the Social Sciences version 22.0. Point estimate was done at a 95% Confidence Interval for frequency and percentages for binary data.
Among 611 total participants, the prevalence of oral potentially malignant disorders was found to be 26 (4.25%) (2.65-5.85 at a 95% Confidence Interval), where males were 19 (73.07%), females were 7 (26.92%), and 23 (88.46%) of them had history of consuming various forms of tobacco, areca nut, and alcohol.
The prevalence of oral potentially malignant disorders in this hospital-based study was found to be lower than previous studies conducted in similar settings.
Nepal; oral cancer; prevalence; tobacco.
Nepal; oral cancer; prevalence; tobacco.
Depression is a common mental health problem among soldiers worldwide. Depression decreases the efficiency and productivity of the soldiers. The objective of this research is to find out the prevalence of depression among armed police force soldiers serving in a police headquarter.
A descriptive cross-sectional study was done on a total of 314 soldiers serving in the eastern regional armed police force headquarters of Nepal from January 15, 2017 to June 14, 2017 after receiving ethical clearance was taken from the Institutional Review Committee (Reference number 140/073/074-IRC). Convenience sampling was done. Beck Depression Inventory was used to assess the prevalence of depression. Data were collected and entered in the Statistical Package for the Social Science version 15.0. which was used for data analysis. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage for binary data.
Among 314 soldiers, 133 (42.36%) (36.89-47.83 at a 95% Confidence Interval) soldiers had depression where, 47 (14.
