Woodarderiksson2923

Snakebite envenomation is a neglected tropical disease which can result in morbidity and mortality. Cardiac implications are poorly understood due to the low frequency of cardiotoxicity combined with a lack of robust information, as snakebites commonly occur in remote and rural areas. This review aims to assess cardiovascular implications of snakebite envenoming and proposes an algorithm for screening of cardiovascular manifestations. Nicotinamide inhibitor A systematic review was performed and 29 articles relating to cardiovascular involvement in snakebite envenomation were selected. link2 Cardiovascular involvement seems to be rare and includes a wide spectrum of outcomes, such as myocardial infarction, ventricular dysfunction, hypotension, cardiac arrest, and myocarditis. In a significant proportion of the cases analyzed (24.39%), the cardiovascular manifestations had major consequences (cardiac arrest, myocardial infarction, malignant ventricular arrhythmias, or death). Clinical monitoring, physical examination, and early electrocardiogram should be considered as key measures to detect cardiovascular involvement in patients with evidence of systemic illness.

The issues faced by young people transitioning out of government care are complex, and improving outcomes requires the collaboration of multiple stakeholders (Lopez & Allen, 2007).

In Vancouver, Western Canada, 60 agencies and 20 youth from government care are working in partnership using a collective impact approach to address the systemic issues and barriers to healthy development that youth from care experience. Collective impact is an approach to tackling complex social problems which requires collaboration across government, business, funders, charitable organizations, and community members to achieve significant and lasting social change (Hanleybrown et al., 2012). The Vancouver collective operates working groups (co-chaired by youth with care experience) that are addressing challenges in the areas of education, employment, housing, meaningful connections (e.g., sustainable family-type supports), health, wellness and culture.

A mixed-method evaluation has included quantitative and qualitative data, collected through outcomes, diaries, surveys, and focus groups, to measure process and outcomes.

Findings help to inform the ongoing development and activities of the collective. Findings indicate the collective is making progress in meeting its goals. Partners continue to be engaged and committed to improving outcomes for youth transitioning out of care, and there are improvements in a number of key areas such as education, collaborative working, and youth engagement.

A collective impact approach that includes youth's voices, and collaboration across multiple stakeholders, can increase the likelihood of improving outcomes for young people transitioning out of government care.

A collective impact approach that includes youth's voices, and collaboration across multiple stakeholders, can increase the likelihood of improving outcomes for young people transitioning out of government care.

Children exposed to violence are at risk of a range of adverse outcomes. Given the unique cultural and social context, understanding what fosters children's resilience in resource-limited areas such as sub-Saharan Africa, is vital.

Using data from the International Survey of Children's Well-Being (ISCWeB), this paper explores individual-, family-, and school-level factors associated with positive outcomes for children who have experienced some form of violence in Khomas region, Namibia.

Using a cross-sectional survey design, the ISCWeB questionnaire, assessing cognitive, affective, and psychological dimensions of well-being, child protection factors and violence exposure was administered to 2124 Grade four and six children.

Our sample had a mean age of 11.2 years. Overall, 56.8 % of children reported at least one incident of violence from an adult caregiver at home and 86.0 % of children reported some form of peer violence at school. Materially deprived children experienced higher incidence of both family and peer violence. The quality of children's relationships at home (β = 0.17, p < 0.001), and school (β = 0.07, p < 0.001) emerged as important protective factors for children's well-being for both types of violence, suggesting that supportive family and school relationships may be more important to the subjective well-being of children who experienced violence than material wellbeing, violence severity, and individual child factors.

Providing positive social interaction and emotional security in contextually and culturally appropriate ways within children's proximal systems should be prioritized while challenging norms that support violence in Namibian families and schools.

Providing positive social interaction and emotional security in contextually and culturally appropriate ways within children's proximal systems should be prioritized while challenging norms that support violence in Namibian families and schools.

the frequency of distal femur fractures in the elderly is rapidly increasing. A study of these fractures was conducted in our center in order to evaluate the comorbidities and the mortality associated with this entity.

all the distal femur fractures by low energy in patients over 65 years old at a tertiary center were included, between January 2010 and December 2016. Baseline characteristics, the type of fracture, comorbidities, and functional status before admission, were collected. The relationship of each of these variables to the final functional class, immediate and late complications and mortality during the follow-up. Fifty-nine patients were included, with a median age of 85.3 years (IQR 78.6-91.6). Fifty-one patients were women. In 10 patients, the fractures were atraumatic (postural change mainly in non-walking patients), and in 54 of the cases were treated surgically (6 with retrograde intramedullary nailing and 48 with lateral locking plate). The median time to surgery was 4.5 days (IQR 2-6) a time to surgery.

To determine whether vaginal progesterone for programmed endometrial preparation is noninferior to intramuscular progesterone in terms of live birth rates from frozen embryo transfer (FET).

Three-armed, randomized, controlled noninferiority trial.

Multicenter fertility clinic.

A total of 1,346 volunteer subjects planning vitrified-warmed transfer of high-quality nonbiopsied blastocysts were screened, of whom 1,125 subjects were ultimately enrolled and randomly assigned to treatment.

The subjects were randomly assigned to receive, in preparation for FET, 50 mg daily of intramuscular progesterone (control group), 200 mg twice daily of vaginal micronized progesterone plus 50 mg of intramuscular progesterone every third day (combination treatment), or 200 mg twice daily of vaginal micronized progesterone.

The primary outcome was live birth rate per vitrified-warmed embryo transfer. The secondary outcomes were a positive serum human chorionic gonadotropin test 2 weeks after FET, biochemical pregnancy loss, clinical pregnancy, clinical pregnancy loss, total pregnancy loss, serum luteal progesterone concentration 2 weeks after FET, and patient's experience and attitudes regarding the route of progesterone administration, on the basis of a survey administered to the subjects between FET and pregnancy test.

A total of 1,060 FETs were completed. The live birth rate was significantly lower in women receiving only vaginal progesterone (27%) than in women receiving intramuscular progesterone (44%) or combination treatment (46%). Fifty percent of pregnancies in women receiving only vaginal progesterone ended in miscarriage.

The live birth rate after vaginal-only progesterone replacement was significantly reduced, due primarily to an increased rate of miscarriage. Vaginal progesterone supplemented with intramuscular progesterone every third day was noninferior to daily intramuscular progesterone, offering an effective alternative regimen with fewer injections.

NCT02254577.

NCT02254577.This paper tackles the global polynomial periodicity (GPP) and global polynomial stability (GPS) for proportional delay Cohen-Grossberg neural networks (PDCGNNs). By adopting two transformations, designing opportune Lyapunov functionals (LFs) with tunable parameters and taking inequality skills, several delay-dependent criteria of GPP and GPS are acquired for the PDCGNNs. Here the GPP is also a kind of global asymptotic periodicity (GAP), but it has obvious convergence rate and convergence order, and its convergence rate is slower than that of global exponential periodicity (GEP). This is of great significance to the detailed division of periodicity in theory. These acquired criteria are confirmed by a numerical example with four cases. Simultaneously, through the numerical example, the acquired criteria also fully demonstrate their superiority in comparison with existing results. And, in another example, a GPS criterion is used to solve a quadratic programming problem (QPP) to reflect one of the practical applications of the PDCGNNs.This paper presents a collaborative obstacle avoidance algorithm of multiple bionic snake robots in fluid based on IB-LBM. The method can make the multiple bionic snake robots avoid different obstacles in the fluid under the control of the improved Serpenoid curve function. The proposed method has high parallelism, can simulate the complex non-linear phenomenon of the multiple snake robots, deal with the complex boundary conditions of the robot, and reduce the conversion of the computational grid. Firstly, a non-linear fluid model is established by LBM, which solves the non-linear problem that the classical Navier-Stokes equations cannot explain the random motion. Secondly, the force source boundary model of multiple bionic snake robots is established by IBM, which saves the calculation time, improves the calculation efficiency and system stability. After that, each bionic snake robot is given a special force to make the robots collaborate with each other and non-colliding with each other in the process of the obstacle avoidance. Finally, through simulation experiments, the trajectory of multiple bionic snake robots avoiding different number of the obstacles in the fluid is analyzed and the collaborative obstacle avoidance process of multiple bionic snake robots in fluid is observed. The validity of the collaborative obstacle avoidance algorithm of multiple bionic snake robots in fluid based on the IB-LBM is verified.Model uncertainties, unknown disturbances, and sensors measurement noises affect the attitude tracking control performance of quadrotors. In this article, a novel robust adaptive recursive sliding mode control (ARSMC) strategy is proposed for the quadrotor to improve the attitude tracking performance and disturbance rejection. Firstly, recursive sliding mode control is introduced, including a two-layer sliding surface, an integral sliding surface, and a fast nonsingular terminal sliding surface, which are recursive. Both sliding surfaces converge to zero in turn. And the initial value of the integral sliding surface is designed to eliminate the reaching phase. Besides, the adaptive gain adjustment method is presented to make an estimate of the unknown upper bound of disturbances. link3 It is proved that the attitude control system has the finite-time convergence and the attitude tracking error will converge to zero. A quadrotor attitude test platform is built to evaluate the proposed algorithm. For comparison, twisting controller (TC), cascade PID, and active disturbance rejection control (ADRC) algorithms are introduced.