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Nano-gold specific adsorption of L-cysteine was also demonstrated by cyclic voltammetry using paraffine-impregnated graphite electrodes with deposited Au NPs. We demonstrate that the superior chemical selectivity and surface sensitivity of ToF-SIMS, via detection of elemental and molecular species, provide a unique ability to identify the adsorption of cysteine and formation of gold-cysteine bonds on Au NPs.Organic spacers play an important role in 2D/3D hybrid perovskites, which could combine the advantages of high stability of 2D perovskites and high efficiency of 3D perovskites. Here, a class of aromatic formamidiniums (ArFA) was developed as spacers for 2D/3D perovskites. It is found that the bulky aromatic spacer ArFA in 2D/3D perovskites could induce better crystalline growth and orientation, reduce the defect states, and enlarge spatially resolved carrier lifetime thanks to the multiple NH···I hydrogen-bonding interactions between ArFA and inorganic [PbI6]4- layers. As a result, compared to the control device with efficiency of 19.02%, the 2D/3D perovskite device based on such an optimized organic salt, namely benzamidine hydrochloride (PhFACl), exhibits a dramatically improved efficiency of 22.39% along with improved long-term thermal stability under 80 °C over 1400 h. Importantly, a champion efficiency of 23.36% was further demonstrated through device engineering for PhFACl-based 2D/3D perovskite solar cells. These results indicate the great potential of this class of ArFA spacers in highly efficient 2D/3D perovskite solar cells.The authors wish to make the following correction to this paper [...].The article cited above [...].In this study, we numerically investigated the effect of swirl inserts with and without nanofluids over a range of Reynolds numbers for parabolic trough collectors with non-uniform heating. Three approaches were utilized to enhance the thermal-hydraulic performance-the variation of geometrical properties of a single canonical insert to find the optimized shape; the use of nanofluids and analysis of the effect of both the aforementioned approaches; the use of swirl generators and nanofluids together. Results revealed that using the straight conical strips alone enhanced the Nusselt number by 47.13%. However, the use of nanofluids along with the swirl generators increased the Nusselt number by 57.48%. These improvements reduced the thermal losses by 22.3% for swirl generators with nanofluids, as opposed to a reduction of only 15.7% with nanofluids alone. The investigation of different swirl generator designs showed various levels of improvements in terms of the overall thermal efficiency and thermal exergy efficiency. The larger swirl generator (H30mm-θ30°-N4) with 6% SiO2 nanofluids was found to be the optimum configuration, which improved the overall collector efficiency and thermal exergy by 14.62% and 14.47%, respectively.We investigated the factors affecting recurrence-free survival in patients with non-B non-C hepatocellular carcinoma (HCC) who received curative treatment. Decision-tree analysis was performed in 72 curative cases of non-B non-C HCC to extract the risk factors for recurrence. read more The reliability of the extracted risk factors was evaluated using the Kaplan-Meier method and the Cox proportional hazards model. The decision-tree analysis extracted three factors-visceral adipose tissue (VAT) index (VATI; less then 71 and ≥71 cm2/m2), which was the cross-sectional areas of VAT on the computed tomographic image at the umbilical level, normalized by the square of the height, fasting immunoreactive insulin (FIRI; less then 5.5 and ≥5.5 µU/mL), and alpha-fetoprotein (AFP; less then 11 and ≥11 ng/mL). The Cox proportional hazards model showed that VATI (hazard ratio (HR) 2.556, 95% confidence interval (CI) 1.191-5.486, p = 0.016), FIRI (HR 3.149, 95% CI 1.156-8.575, p = 0.025), and AFP (HR 3.362, 95% CI 1.550-7.288, p = 0.002) were all independent risk factors for HCC recurrence. Non-B non-C HCC patients with a higher VATI (≥71 cm2/m2) or higher FIRI (≥5.5 µU/mL) and AFP (≥11 ng/mL) if VATI was less then 71 cm2/m2 are prone to recurrence after curative treatment.In this Special Issue, a wide variety of original and review articles provide a timely overview of how viruses are recognized by and evade from cellular innate immunity, which represents the first line of defense against viruses [...].A new hypothesis highlights sleep-dependent learning/memory consolidation and regards the sleep-wake cycle as a modulator of β-amyloid and tau Alzheimer's disease (AD) pathologies. Sundowning behavior is a common neuropsychiatric symptom (NPS) associated with dementia. Sleep fragmentation resulting from disturbances in sleep and circadian rhythms in AD may have important consequences on memory processes and exacerbate the other AD-NPS. The present work studied the effect of training time schedules on 12-month-old male 3xTg-AD mice modeling advanced disease stages. Their performance in two paradigms of the Morris water maze for spatial-reference and visual-perceptual learning and memory were found impaired at midday, after 4 h of non-active phase. In contrast, early-morning trained littermates, slowing down from their active phase, exhibited better performance and used goal-directed strategies and non-search navigation described for normal aging. The novel multitarget anticholinesterasic compound AVCRI104P3 (0.6 µmol·kg-1, 21 days i.p.) exerted stronger cognitive benefits than its in vitro equipotent dose of AChEI huprine X (0.12 μmol·kg-1, 21 days i.p.). Both compounds showed streamlined drug effectiveness, independently of the schedule. Their effects on anxiety-like behaviors were moderate. The results open a question of how time schedules modulate the capacity to respond to task demands and to assess/elucidate new drug effectiveness.Retinoblastoma is a rare type of cancer, and its treatment, as well as diagnosis, is challenging, owing to mutations in the tumor-suppressor genes and lack of targeted, efficient, cost-effective therapy, exhibiting a significant need for novel approaches to address these concerns. For this purpose, nanotechnology has revolutionized the field of medicine with versatile potential capabilities for both the diagnosis, as well as the treatment, of retinoblastoma via the targeted and controlled delivery of anticancer drugs via binding to the overexpressed retinoblastoma gene. Nanotechnology has also generated massive advancements in the treatment of retinoblastoma based on the use of surface-tailored multi-functionalized nanocarriers; overexpressed receptor-based nanocarriers ligands (folate, galactose, and hyaluronic acid); lipid-based nanocarriers; and metallic nanocarriers. These nanocarriers seem to benchmark in mitigating a plethora of malignant retinoblastoma via targeted delivery at a specified site, resulting in programmed apoptosis in cancer cells.