Wellsholm7098

Smokeless tobacco (SLT) causes significant harm to the oral cavity and is considered a risk factor for oral cancer. Various forms, products, and patterns of SLT are used across different populations. Many products, such as nicotine and betel nut, have addictive and carcinogenic properties. SLT use is associated with benign, premalignant, or malignant lesions. This study aimed to identify the characteristics of these oral lesions and their association with SLT exposure.

This cross-sectional study, performed at our institution's Faculty of Dentistry, included all the patients with a history of using SLT within a 5-year period at the oral medicine clinic. The patients' demographic details were collected, and information regarding habit, duration, frequency, site of placement, and history of habit discontinuity were recorded. If a biopsy was performed, the diagnoses were also reported.

Of the 59 patients included, 89.8% were male and 10.2% were female. SLT lesions in the oral cavity were usually focal lesions (76.3%). The most preferred placement site by SLT users was the mandibular posterior vestibule. Follow-up of SLT patients after quitting or clinical changes in the placement site showed a 92.8% regression or complete healing of the lesions. Of the 59 patients who underwent SLT, 18.6% were diagnosed with oral squamous cell carcinoma.

This study demonstrated a high percentage of remarkable regression or complete healing of SLT lesions related to early diagnosis and habit change. In contrast, 18.6% of the lesions progressed to SCC.

This study demonstrated a high percentage of remarkable regression or complete healing of SLT lesions related to early diagnosis and habit change. In contrast, 18.6% of the lesions progressed to SCC.

The appraisal of research productivity is one of the key indicators to evaluate any area of knowledge. The current study aimed to analyze the Scopus-indexed publications on endodontics produced by Gulf Cooperation Council (GCC) region from 2000 to 2020.

The dataset was extracted in May 2021 from Elsevier's Scopus database. Two keywords ("endodontic" and "endodontics") were entered into the basic search with the Boolean operator of OR for a period of 20years from 2000 to 2020.

Overall, the GCC region contributed 2.82% of the global endodontic research. This share has shown a remarkable increase between 2001 and 2020 from 0.82% to 7.20%. About 60% of documents' volumes were produced during the 2016-2020 period. Around 80% of research was produced by Saudi Arabia, while research articles produced by Kuwait gained the highest citation impact. Out of the ten productive institutions, nine belonged to Saudi Arabia and one was from Kuwait. The majority of research collaboration was conducted with the United States, but research articles produced in collaboration with Japan yielded the highest citation impact.

The study highlighted various scientometric attributes of endodontic publications produced by GCC affiliated researchers. The ongoing growth of endodontic literature by GCC countries along with the increasing international collaboration is considered aspiring.

The study highlighted various scientometric attributes of endodontic publications produced by GCC affiliated researchers. The ongoing growth of endodontic literature by GCC countries along with the increasing international collaboration is considered aspiring.

The aims of this study were to create Bisphonates Related Osteonecrosis of the Jaw (BRONJ) in rats and treat them with an angiogenesis factor (A-Heal) and ABMDO (Autologous Bone Marrow Derived Osteoblasts).

Thirty female Wistar rats were procured. Rats were labeled as Group I to III. Group I=Osteoblast group, Group II=A-Heal and Group III Control group. In Groups I-III, BRONJ was created and treated in Group I with ABMDO, Group II with A-Heal and Group III was the control group. At the end of the four weeks post treatment, all the animals were humanely killed. The intact maxillae were removed in total. Histopathological and radiological examinations were carried out with physicians blinded to the groups.

Computerized tomography revealed that Groups I and II demonstrated the presence of dense osteosclerosis, intralesional calcifications, and adequate healing of the overlying soft tissues compared to Group III, which showed the presence of bone erosions at the alveolar ridge with a lack of intralesional calcifications and ulceration of the overlying soft tissues. Histologically, H&E staining Group 1 and Group 2 both showed marked reactive bone formation. Group 2 additionally revealed the most prominent vascular proliferation (also highlighted by Factor VIII, an endothelial cell marker) among all groups. Group 3 showed cartilaginous proliferation with less reactive bone formation, implicating decreased endochondral ossification compared to Groups 1 and 2.

This study shows that angiogenesis factor (A-Heal) and ABMDO were successful in the treatment of experimentally created BRONJ in an animal model.

This study shows that angiogenesis factor (A-Heal) and ABMDO were successful in the treatment of experimentally created BRONJ in an animal model.

Fluid dynamics is a majorly neglected aspect to be studied in root canal irrigation. The fundamental rule to understand mechanics is to observe patterns of flow during the process.Thus, this work is conducted to do a systemic assessment of the in-vitro and ex-vivo based studies to evaluate the effect of various parameters on the irrigant flow and apical pressure on using a manual syringe needle for root canal irrigation.

The literature search was conducted through libraries such as PubMed (Medline), CINAHL, Embase, Scopus and other hand literature from Google Scholar, the British medical library etc. The systematic review was reported following the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. As they include studies that were in-vitro and ex-vivo based, the risk of bias of the selected articles was assessed using a customized tool based on the previous literature and parameters evaluated in the studies included.

The literature search resulted in 101 items of which 19 records were included in this review. Results reported that multiple factors and parameters were assessed to evaluate the flow and apical pressures on using manual syringe needle irrigation.

Present systematic review gives insights in-depth about the irrigation dynamics of manual syringe needle irrigation. Besides, it is inconclusive to compile a single factor or a single parameter contributing to the enhanced irrigant flow and least apical pressures.

Present systematic review gives insights in-depth about the irrigation dynamics of manual syringe needle irrigation. Besides, it is inconclusive to compile a single factor or a single parameter contributing to the enhanced irrigant flow and least apical pressures.

The aim of this systematic review was to address the clinical effectiveness of space maintainers and space regainers in the prevention and correction of dental arch decreases in mixed dentition.

An electronic search was conducted using five databases the Cochrane Database for Systematic Reviews, EBSCO Host, ScienceDirect, PubMed, and Scopus (until February 2021) and 6 relevant journals. Inclusion criteria were Randomized Controlled Clinical Trials (RCTs), Controlled Clinical Trials (CCTs), cohort studies and case-control studies of children in the mixed dentition requiring a space maintainer or a space regainer, children with mild to moderate crowding, and with Class I and mild Class II or Class III skeletal pattern. All articles included in this review were examined independently by three teams of investigators to assess the level of bias using the Cochrane risk of bias tools RoB 2.0 (for RCTs) and ROBINS-I (for non-RCTs).

Following the three phases of a systematic search, 11 studies were included for evidence provided by this systematic review, high-quality studies are needed.

This retrospective study aimed to compare radiodensity measurements and Goutallier grading systems for the evaluation of fatty infiltration in hip abductors.

The radiodensity of the gluteus minimus and medius muscles was measured in 80 hips of 40 patients. These muscles were graded for fatty infiltration using three five-grade classification systems the original Goutallier classification on both computed tomography (CT) and magnetic resonance imaging (MRI), and a new objective classification based on the percentage of the functional muscle area (defined as 30-100 Hounsfield units). After measuring and grading the abductors, correlation coefficients between them were analyzed.

Spearman's rank correlation coefficients (ρ) between radiodensity measurements of abductors and the Goutallier classification on CT and MRI were -0.701 and -0.552 for the gluteus minimus and -0.832 and -0.740 for the gluteus medius, respectively. 8-Cyclopentyl-1,3-dimethylxanthine ic50 Our new classification had correlation coefficients of -0.844 and -0.926 for the gluteus minimus and gluteus medius, respectively.

Radiodensity measurements showed a strong correlation with the grading systems, particularly with the new classification based on the percentage of the functional muscle area. Considering the subjective nature of the original Goutallier grading systems, we conclude that radiodensity assessment is feasible and more objective for evaluating fatty infiltration in hip abductors.

Radiodensity measurements showed a strong correlation with the grading systems, particularly with the new classification based on the percentage of the functional muscle area. Considering the subjective nature of the original Goutallier grading systems, we conclude that radiodensity assessment is feasible and more objective for evaluating fatty infiltration in hip abductors.

In total hip arthroplasty (THA) for patients with previous femoral osteotomy, we hypothesized that a tapered cone stem may be an option due to the altered morphology of the proximal femur. The purpose of this study was to assess the short-term results of THA after femoral osteotomy using a tapered cone stem, and to identify issues that require further attention.

Twenty-two hips in 21 consecutive patients who underwent THA after femoral osteotomy using a Wagner Cone tapered cone stem were retrospectively reviewed, with a mean follow-up period of 34.4 (range, 24-50) months. Clinical information was obtained from medical records. On preoperative radiographs, the Dorr type was classified based on the anteroposterior cortical index. On postoperative radiographs, the degree of stem subsidence and the stem location with the highest canal fill ratio were assessed.

The mean Harris hip score significantly improved from 55.2at baseline to 84.8at final follow-up. Radiologically, stem subsidence (>3mm) was observed in seven hips, and it stabilized within 1 year after THA in all cases. In five of seven hips with stem subsidence, the highest postoperative canal fill ratio was observed in the distal third of the stem. The proportions of males and Dorr type A were significantly higher among hips with stem subsidence than among those without. During the follow-up period, no hips showed implant loosening or required revision surgery.

The occurrence of stem subsidence should be noted when using Wagner Cone stems for Dorr type A femurs after femoral osteotomy.

The occurrence of stem subsidence should be noted when using Wagner Cone stems for Dorr type A femurs after femoral osteotomy.