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t theoretical models. It shows excellent psychometric properties, which render it extremely useful for both clinical and research use. click here To date, the KEPAQ is the only disease-specific scale worldwide to evaluate both functional and emotional compromise in keratoconus patients.Purpose To evaluate the safety and efficacy of non-penetrating deep sclerectomy with a collagen implant versus trabeculectomy in primary congenital glaucoma. Subjects and methods This was a retrospective interventional comparative non-randomized clinical study that included 80 eyes of 80 children presenting with primary congenital glaucoma under the age of 3 years. Forty eyes have undergone non-penetrating deep sclerectomy (NPDS) and the other 40 eyes have undergone penetrating trabeculectomy. The main outcome measure was the reduction in intraocular pressure (IOP). Secondary outcomes included percentage of patients with complete and qualified success, need for topical antiglaucoma medications, rate of complications, and need for further interventions. Complete success of the surgical outcome was considered an IOP ≤16 mmHg with no antiglaucoma medications. Qualified success was considered an IOP ≤16 mmHg using antiglaucoma medications. Results The mean preoperative IOP was 27.4 ± 6.9 and 28.5 ± 6.6 mmHg in NPomparison to penetrating trabeculectomy with a comparative postoperative reduction in the intraocular pressure and overall success rates. Trial registration The trial was registered on 11/01/2020 with number PACTR202002874953456 (https//pactr.samrc.ac.za).Background and aim We investigated the in vivo changes of artery diameter (AD) and vein diameter (VD) after topical phenylephrine 2.5% instillation, and its relationship with the Systematic Coronary Risk Evaluation (SCORE). Methods This is a cross-sectional study. Healthy control patients were included. All of the participants underwent enhanced depth imaging by spectral-domain optical coherence tomography before and 30 minutes after phenylephrine instillation, using eye-tracking and follow-up software. Changes in AD and VD were assessed. Results The study included 45 eyes of 45 patients (14 males and 31 females). The mean age was 58.6 ± 15.1 years (26-88 years). Mean SCORE risk estimation value was 2.0 (0-14). No significant correlation was found between pre-phenylephrine AD or VD with age (p=0.237 and p=0.821, respectively), SCORE (p=0.545 and p=0.723, respectively). AD significant thinned after phenylephrine (p less then 0.001), whereas no significant changes could be depicted in VD (p=0.474). Changes in AD after phenylephrine were significantly related with SCORE risk estimation (p=0.035). Discordantly, changes in VD after phenylephrine were not significantly related with SCORE (p=0.505). Conclusion As a significant thinning of AD occurred following phenylephrine instillation, and as the magnitude of this thinning is related with SCORE, it is useful to test the retinal artery contraction to infer the cardiovascular health status.The hydraulic conductivity of the vitreous humor has been measured for the bovine eye. The experiment was carried out by placing it within upright cylindrical chamber, open at both ends, and letting its liquid content drain out of the bottom opening by gravity, through a 20μm nylon mesh filter. Additional negative pressure was provided at the exit by a hanging drainage tube. The diminishing vitreous volume was measured in terms of the height in the chamber and recorded as a function of time. The reduction in the vitreous liquid content also caused the hydraulic conductivity to reduce and this parameter was quantified on the basis of previously-developed theories of fibrous porous media that have been very well established. A theoretical model with a fully analytical expression for the vitreous volume undergoing drainage was developed and used as a least-squares best fit to deliver the initial hydraulic conductivity value of K 0/μ=(7.8 ± 3.1) × 10-12 m2 (Pa-s). The measurements were made with the hyaloid membrane intact and therefore represents an effective conductivity for the entire system, including possible variations within the vitreous.Background The bottleneck in upper limb prosthetic design is the myoelectric control algorithm. Here we studied the clinical readiness of the myoelectric postural control algorithm in a laboratory setting with two trans-radial amputees using a commercially available prosthetic limb system. link2 Technique The postural control algorithm was integrated into prosthetic limb systems using standard of care components. A comparison between a commercial state of the art system (the i-limb revolution state-based myoelectric controller) and the postural controller was performed with two people with trans-radial amputation using a self-contained prosthesis system. Discussion The performance using the i-limb revolution state-based controller versus the postural controller was mixed based on the Southampton Hand Assessment Procedure. The SHAP scores indicate that the postural controller with i-limb revolution provided an average of 66% of hand function compared to an intact limb. Future work will study the advantages of the postural control algorithm in everyday use.Background Various surgical approaches exist for Total Hip Arthroplasty (THA), but approach specific complication rates remain unknown. The purpose of this systematic review and meta-analysis was to compare rates of common complications between surgical approaches. Methods Four electronic databases (Medline, Embase, AMED, Ovid Healthstar) were searched from inception to June 2019. Three pairs of reviewers were involved in determining eligibility, rating internal and external validity, and data extraction. Pooled estimates were generated using a random-effects model and relative risk (RR) was calculated for dislocation, intraoperative and early postoperative fracture, early infection, deep vein thrombosis (DVT), wound complication, and failure of implant ingrowth between four approaches (posterior, anterior, direct lateral, and anterolateral). Results Sixty-nine studies (n = 283,036) were included with nineteen randomized control trials, fourteen prospective cohort, and thirty-six retrospective cohort studies pproach has its own strengths and weaknesses, and surgeons can use the approach they are most comfortable with.As the population ages and as people live longer, there is a growing demand for total hip and total knee procedures. Possible outcomes for these procedures is a postoperative joint infection (PJI) that can cause long postoperative lengths of stay (LOS) in the hospital. The PJIs can also negatively impact the quality of life for the patient. Using the roadmap of the continuous quality improvement theory, the purpose of this quantitative study was to examine the relationship between the independent variables (joint education class participation, body mass index [BMI], A1c, and smoking) and dependent variables (PJI and LOS). To evaluate the relationship with PJI, a logistical regression analyzed the sample population of 1216 patients and indicated a relationship between joint education class attendance and PJI among total hip patients, but not total knee patients when controlling for the other variables. The regression also indicated a significant relationship between BMI and smoking and PJIs, but it did not show a relationship between A1c/diabetes and PJI. To evaluate the relationship between joint class education and LOS a Poisson regression indicated that those who did not attended the joint education class, whether they had total hips or total knees, had a longer postoperative LOS. The implications for positive social change involve providing information to physicians and administrators regarding the effectiveness of the total joint education class in improving outcomes. This information could be used to justify the need for patient compliance with the class and/or the possible need for additional resources to support the total joint education program.Currently, in the European Union (EU), e-waste chain performance is assessed by technical indicators that aim to ensure system compliance with collection and recovery targets set by the WEEE Directive. This study proposes indicators to improve WEEE flow monitoring beyond the current overall weight-based approach, including complementary flows and treatment performance. A case study focused on the screen category in France is presented. In 2017, the collection rate of cathode-ray tube screens (CRT) was 68%, while for flat panel display (FPD) generated only 14% was collected. CRT screens have less precious and critical materials than FDP. Thus, elements like cobalt and gold highly concentrated in FPD, have a collection rate two to four times lower than elements such as copper (37%) which represents a high proportion in CRTs. Recycling is the main treatment in France. Nevertheless, the recycling rate per element varies significantly due to the low collection, and also the lack of technology and/or secondary raw materials market. The elements with higher recycling rates are base metals such as copper (28%), followed by precious metals like silver (23%), and gold (13%). Except for palladium, the recycling rate of the critical raw materials targeted in the study ranged from 6% (cobalt) to 0% (e.g. neodymium and indium). link3 The results stress the need for indicators to support the development of WEEE chain from waste management to secondary (critical) raw materials suppliers.The concept of resources or materials dissipation after their use in the technosphere has been increasingly considered in life-cycle based studies, applying Substance and Material Flow Analysis (SFA and MFA), Input-Output Analysis, and Life Cycle Assessment (LCA). However, there is currently no common understanding of what a dissipative flow is. This article first reviews 45 publications to describe the status of resource dissipation in life-cycle based studies, discussing how resource dissipation is usually defined, which temporal perspective is considered, which compartments of dissipation are distinguished, and which approaches (including the implementation of parameters) are considered to assess resource dissipation in a system. Moreover, this article proposes a comprehensive definition of resource dissipation, building from the literature review and focusing on abiotic resources. It then discusses this definition with respect to its potential implementation in LCA considering today's existing Life Cycle Inventory (LCI) datasets and best practices. Overall it shows that the LCA framework may be well suited to assess abiotic resource dissipation. In particular i) the compartments of dissipation usually considered in the literature are covered in LCA, and ii) LCI databases could be a source of information to be further used to quantify a set of flows defined as "dissipative", as commonly considered in SFA/MFA studies. However, major challenges are still faced before any potential routine implementation in LCA. The article accordingly discusses the potential way forward in the short-term (development and test of possible approaches), mid-term (towards satisfactory robustness, and consensus) and long-term (large-scale changes of LCI databases).

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