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ADHD Medication During Pregnancy and Breastfeeding
Women suffering from ADHD face a difficult decision regarding whether or not to stop taking ADHD medication during pregnancy and breast-feeding. There aren't enough data regarding how exposure over time may affect the foetus.
A study recently published in Molecular Psychiatry shows that children exposed to ADHD medication in the uterus don't develop neurological disorders like hearing or vision impairment seizures, febrile seizures, or IQ impairment. The authors acknowledge the need for more high-quality research.
Risk/Benefit Analysis
Women who are expecting and taking ADHD medication must consider the benefits of taking it against the possible risks for the fetus. Physicians don't have the data to give clear advice but they can provide information about risks and benefits to aid pregnant women in making informed choices.
A study published in Molecular Psychiatry concluded that women who were taking ADHD medication in early pregnancy were not at a greater risk of fetal malformations, or structural birth defects. Researchers used a large sample-based case control study to compare the incidence of major structural defects in infants who were born to mothers who used stimulants during pregnancy. Pediatric cardiologists and clinical geneticists examined the cases to ensure an accurate case classification and to minimize the chance of bias.
The study of the researchers was not without limitations. The researchers were unable in the beginning to distinguish the effects caused by the medication from the disorder. This makes it difficult to determine whether the limited associations observed in the groups that were exposed are due to the use of medication or comorbidities that cause confusion. Researchers also did not look at long-term outcomes for the offspring.
The study found that babies whose mothers had taken ADHD medication during pregnancy had a slightly greater risk of being admitted to the neonatal care unit (NICU) as compared to mothers who did not use any medication during pregnancy or discontinued taking their medication prior to or during pregnancy. This increase was due to central nervous system-related disorders and the increased risk for admission was not found to be influenced by which stimulant medications were taken during pregnancy.
Women who were taking stimulant ADHD medications during pregnancy also had a higher chance of having caesarean sections or one whose baby scored low on the Apgar scale (less than 7). These increases didn't seem to be influenced by the kind of medication used during pregnancy.
The research suggests that the small risk associated with the use of ADHD medications during early pregnancy may be offset by the higher benefit for both mother and child of continued treatment for the woman's condition. Physicians should discuss the issue with their patients and, if possible, assist them in developing strategies to improve coping skills which can reduce the negative impact of her condition on her daily functioning and relationships.
Medication Interactions
Doctors are increasingly confronted with the dilemma of whether to maintain treatment or stop as more women are diagnosed with ADHD. These decisions are usually taken without clear and authoritative evidence. Instead, doctors have to consider their own expertise and experience, as well as the experiences of other physicians and the research on the topic.
The issue of possible risks for infants can be extremely difficult. The research on this subject is based on observations rather than controlled studies, and a lot of the results are in conflict. Additionally, the majority of studies limit their analysis to live births, which could undervalue the serious teratogenic effects that can lead to abortion or termination of the pregnancy. The study discussed in this journal club addresses these limitations by examining data on both live and deceased births.
Conclusion A few studies have revealed an association between ADHD medications and certain birth defects however, other studies haven't established a link. Most studies have shown a neutral, or even somewhat negative, impact. As a result, a careful risk/benefit analysis is required in every situation.
For women suffering from ADHD and ADD, the decision to discontinue medication is difficult, if not impossible. In a recent article in the Archives of Women's Mental Health by psychologist Jennifer Russell, she notes that stopping ADHD medications during pregnancy can cause depression and feelings of loneliness. Furthermore, a loss of medication can interfere with the ability to do job-related tasks and drive safely, which are important aspects of daily life for many people with ADHD.
She recommends women who are uncertain about whether or not to stop medication in light of their pregnancy should consider informing family members, friends, and coworkers on the condition, its effects on daily functioning, and the advantages of continuing the current treatment regimen. It can also help a woman feel more confident in her decision. It is also worth noting that some drugs can be absorbed through the placenta therefore, if a patient decides to stop her ADHD medication during pregnancy and breastfeeding, she should be aware that traces of the drug could be passed on to the baby.
Birth Defects and Risk of
As the use of ADHD drugs to treat symptoms of attention deficit hyperactivity disorder (ADHD) grows there are concerns about the effects that the drugs could have on foetuses. A recent study published in the journal Molecular Psychiatry adds to the body of knowledge about this subject. Researchers used two huge data sets to examine over 4.3 million pregnant women and determine if stimulant medication use increased the risk of birth defects. Researchers found that while the risk overall is low, first-trimester ADHD exposure to medication was associated with slightly higher risk of certain heart defects, like ventriculoseptal defect.
The researchers of the study found no connection between early medication use and congenital abnormalities like facial clefting, or club foot. The results are in line with previous studies showing an increase, but not significant, in the risk of heart malformations in women who started taking ADHD medications before the time of pregnancy. This risk increased during the latter part of pregnancy, as many women begin to discontinue their medication.
Women who were taking ADHD medication in the first trimester were more likely to require a caesarean birth, have an insufficient Apgar after birth and have a baby that needed breathing assistance at birth. However the authors of the study were unable to eliminate bias due to selection by restricting the study to women who didn't have other medical issues that could have contributed to these findings.
Researchers hope that their research will help doctors when they encounter pregnant women. They suggest that although discussing the benefits and risks is important but the decision to stop or keep treatment must be based on each woman's needs and the severity of her ADHD symptoms.
The authors also advise that, while stopping the medication is an option, it isn't an option that is recommended due to the high incidence of depression and other mental health issues in women who are pregnant or who are recently post-partum. Further, the research suggests that women who choose to stop taking their medications are more likely to experience difficulties getting used to life without them following the birth of their baby.
Nursing
It can be overwhelming to become a mom. Women who suffer from ADHD who have to manage their symptoms while attending doctor appointments and preparing for the arrival of a baby and getting used to new routines at home may face a lot of challenges. Many women choose to continue taking their ADHD medication during pregnancy.
The risk for breastfeeding infant is not too high since the majority of stimulant medication passes through breast milk at a low level. The rate of medication exposure will differ based on dosage and frequency of administration as well as the time of day. Additionally, individual medications enter the baby's system differently through the gastrointestinal tract as well as breast milk and the impact of this on a newborn infant is not yet fully known.
Some physicians may discontinue stimulant medication during a woman's pregnancy due to the lack of research. This is a difficult decision for the patient, who must balance the benefits of continuing her medication against the possible risks to the foetus. In the meantime, until more information is available, GPs can inquire about pregnant patients if they have a history of ADHD or if they are planning to take medication during the perinatal stage.
Numerous studies have proven that women can continue to take their ADHD medication without risk during pregnancy and breast-feeding. As a result, more and more patients are choosing to do so and, in consultation with their physician, they have found that the benefits of maintaining their current medication outweigh any potential risks.
Women with ADHD who plan to breastfeed should seek advice from a specialist psychiatrist prior to becoming pregnant. They should discuss their medication with their doctor, and the pros and cons of continuing treatment. This includes non-pharmacological methods. Psychoeducation is also required to help pregnant people with ADHD understand their symptoms and the root cause Learn about the available treatments and to reinforce existing strategies for coping. This should be a multidisciplinary approach together with obstetricians, GPs, and psychiatrists. adhd treatment without medication for pregnancy should include the discussion of a plan for management for both mother and child, and monitoring for signs of deterioration and when necessary, making adjustments to the medication regimen.