Vestergaardjuul4226

The triple quantum dot system, investigated in this paper, combines fabrication simplicity along with descent cooling power and may pave the way towards the practical realization of efficient nonlocal cryogenic refrigeration systems.We use a random walk particle-tracking (RWPT) approach to elucidate the impact of porous media confinement and cell-cell interactions on bacterial transport. The model employs stochastic alternating motility states consisting of hopping movement and trapping reorientation. The stochastic motility patterns are defined based on direct visualization of individual trajectory data. We validate our model against experimental data, at single-cell resolution, of bacterial E. coli motion in three-dimensional confined porous media. Results show that the model is able to efficiently simulate the spreading dynamics of motile bacteria as it captures the impact of cell-cell interaction and pore confinement, which marks the transition to a late-time subdiffusive regime. Furthermore, the model is able to qualitatively reproduce the observed directional persistence. Our RWPT model constitutes a meshless simple method which is easy to implement and does not invoke ad hoc assumptions but represents the basis for a multiscale approach to the study of bacterial dispersal in porous systems.We study the spectral statistics of quantum systems with finite Hilbert spaces. We derive a theorem showing that eigenlevels in such systems cannot be globally uncorrelated, even in the case of fully integrable dynamics, as a consequence of the unfolding procedure. We provide an analytic expression for the power spectrum of the δ_n statistic for a model of intermediate statistics with level repulsion but independent spacings, and we show both numerically and analytically that the result is spoiled by the unfolding procedure. Then, we provide a simple model to account for this phenomenon, and test it by means of numerics on the disordered XXZ chain, the paradigmatic model of many-body localization, and the rational Gaudin-Richardson model, a prototypical model for quantum integrability.DNA methylation is associated with a number of biological phenomena, and plays crucial roles in epigenetic regulation of eukaryotic gene expression. It is also suggested that DNA methylation alters the mechanical properties of DNA molecules, which is likely to affect epigenetic regulation. selleck chemicals llc However, it has not been systematically investigated how methylation changes the structural and dynamic features of DNA. In this research, to elucidate the effects of methylation on DNA mechanics, a fully atomic molecular dynamics simulation of double-stranded DNA with several methylation patterns was performed. Through the analysis of the relative positioning of the nucleotides (base-step variables), characteristic changes in terms of local flexibility were observed, which further affected the overall DNA geometry and stiffness. These findings may serve as a basis for a discussion on methylation-dependent DNA dynamics in physiological conditions.It is commonly accepted that in typical situations the rate of entropy production is non-negative. We show that this assertion is not entirely correct, not even in the linear regime, if a time-dependent, external perturbation is not compensated by a rapid enough decay of the response function. This is demonstrated for three variants of the Drude model to describe electrical conduction in noble metals, namely the classical free electron gas, the Drude-Sommerfeld model, and the extended Drude-Sommerfeld model. The analysis is concluded with a discussion of potential experimental verifications and ramifications of negative entropy production rates.The mechanics of lower dimensional elastic structures depends strongly on the geometry of their stress-free state. Elastic deformations separate into in-plane stretching and lower energy out-of-plane bending deformations. For elastic structures with a curved stress-free state, these two elastic modes are coupled within linear elasticity. We investigate the effect of that curvature-induced coupling on wave propagation in lower dimensional elastic structures, focusing on the simplest example-a curved elastic rod in two dimensions. We focus only on the geometry-induced coupling between bending and longitudinal (in-plane) strain that is common to both rods in two dimensions and to elastic shells. We find that the dispersion relation of the waves becomes gapped in the presence of finite curvature; bending modes are absent below a frequency proportional to the curvature of the rod. By studying the scattering of undulatory waves off regions of uniform curvature, we find that undulatory waves with frequencies in the gap associated with the curved region tunnel through that curved region via conversion into compression waves. These results should be directly applicable to the spectrum and spatial distribution of phonon modes in a number of curved rod-like elastic solids, including carbon nanotubes and biopolymer filaments.A vibrational model of heat transfer in simple liquids with soft pairwise interatomic interactions is discussed. A general expression is derived, which involves an averaging over the liquid collective mode excitation spectrum. The model is applied to quantify heat transfer in a dense Lennard-Jones liquid and a strongly coupled one-component plasma. Remarkable agreement with the available numerical results is documented. A similar picture does not apply to the momentum transfer and shear viscosity of liquids.We determine the osmotic pressure of microgel suspensions using membrane osmometry and dialysis, for microgels with different softnesses. Our measurements reveal that the osmotic pressure of solutions of both ionic and neutral microgels is determined by the free ions that leave the microgel periphery to maximize their entropy and not by the translational degrees of freedom of the microgels themselves. Furthermore, up to a given concentration it is energetically favorable for the microgels to maintain a constant volume without appreciable deswelling. The concentration where deswelling starts weakly depends on the crosslinker concentration, which affects the microgel dimension; we explain this by considering the dependence of the osmotic pressure and the microgel bulk modulus on the particle size.