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The remaining three samples have deviations in the range from 5.2% to 6.3%. For the gamma scattering technique, there are 17/21 samples with a relative deviation of less than 5%. The remaining four samples have a deviation in the range from 5.2% to 6.9%. The results proved that the artificial intelligence technique combined with Monte Carlo based on gamma transmission and gamma scattering techniques is an effective approach for estimating the density of a liquid.Few places in the world produce iodine-125. In Brazil, the first production was achieved by using the IEA-R1 nuclear reactor located at Nuclear and Energy Research Institute - IPEN. To verify the quality of iodine-125 produced, and the amount of contaminants such as iodine-126, cesium-134 and caesium-137 among others, iodine-125 samples were immobilized into epoxy matrix disc, with the same geometry of a barium-133 reference radioactive source, used to calibrate an HPGe detector. The HPGe detector has a thin carbon composite window, which allows measure the iodine-125 photopeaks, between 27.1 and 35.4 keV. The method employed here was successful in producing and measurement of iodine-125.

Among people with cancer, dual alcohol and tobacco use increases risk for morbidity and mortality. Most smoking cessation clinical trials with this patient population have excluded individuals with problematic alcohol use. This investigation examined whether problematic alcohol use affects smoking cessation in cancer patients.

Mixed-methods secondary analysis of data from the Smokefree Support Study, a randomized-controlled trial examining the efficacy of Intensive (IT; n=153) vs. Standard Treatment (ST; n=150) for smoking cessation in newly diagnosed cancer patients. Problematic alcohol use was assessed at enrollment using the Cut-Down-Annoyed-Guilty-Eye-Opener (CAGE), weekly frequency of alcohol use and binge drinking measures. Alcohol use was categorized as no current alcohol use, moderate and problematic use. Quizartinib chemical structure The primary outcome was biochemically-confirmed cigarette abstinence at 6-months. A subset of patients (n=72) completed qualitative exit-interviews.

Among all participants, biochemically-confir may benefit from smoking and alcohol behavior change interventions at the time of cancer diagnosis.The purpose of the present investigation was to examine the unique explanatory role of alcohol use motives above the effects of each other, using a multiple mediation model, for the relationship between obsessive-compulsive symptomatology and problematic alcohol use among a young ethno-racially diverse sample of college students with current (past-month) alcohol use. Participants were 454 college students (81.72% female, Mage = 22.46, SD = 4.71). Results indicated that coping motives significantly explained the relationship between obsessive-compulsive symptoms, and alcohol consumption (past year), risky drinking, and recent alcohol use (past month) as behavioral indices of problematic drinking after controlling for the variance accounted for by recent cannabis use, smoking, and anxiety and depressive symptoms (with small to medium effect sizes). These findings are discussed in terms of the development of specialized treatments to specifically target coping oriented alcohol use motives in the context of obsessive-compulsive symptoms among young adults with clinically significant OCD symptoms and comorbid problematic alcohol use.

Progressive supranuclear palsy (PSP) is a neurodegenerative disorder with symptoms including vertical gaze palsy, frequent falls, abnormal gait, and cognitive/language/behavioral changes, making diagnosis and treatment challenging.

Descriptive analysis was undertaken of cross-sectional, real-world data for patients with PSP provided by neurologists in France, Germany, Italy, Spain, UK, and USA.

Data on 892 PSP patients were obtained from patient records. Common initial symptoms included difficulty walking/maintaining gait, confusion/disorientation, loss of balance/falling, and rigidity. These symptoms and vertical gaze palsy commonly aided diagnosis. At data collection, dysphagia and blepharospasm were also very common. Mean times from symptom-onset to consulting a healthcare professional and PSP diagnosis were 5.2 and 15.0months, respectively. General practitioners or movement disorder specialists were most commonly consulted initially; 98% of patients were diagnosed with PSP by a movement disorder spegnosis is often delayed. Consulting a movement disorder specialist might expediate diagnosis. Currently, only symptomatic treatments are available with a poor satisfaction, and there is an urgent need for disease-modifying agents.

The progressively disabling and terminal nature of ALS/MND imposes major coping demands on patients. We wished to improve the psychometric properties of our previously published MND-Coping Scale, so that parametric analyses were valid, and to make it simpler for patients to complete and clinicians to score.

After a new qualitative analysis of 26 patients with ALS/MND, the draft Coping Index-ALS (CI-ALS) was administered to 465 additional patients, alongside COPE-60, General Perceived Self Efficacy scale, and WHOQOL-BREF. Validity of the CI-ALS was assessed using the Rasch model. External validity was checked against comparator measures.

Thirteen centres contributed 465 patients, mean age 64.9years (SD 10.8), mean disease duration 28.4months (SD 37.5). The CI-ALS-Self and CI-ALS-Others both satisfied Rasch model expectations and showed invariance across age, gender, marital status and type of onset. Expected correlations were observed with comparator scales. A nomogram is available to convert the raw scores to interval level measures suitable for parametric analysis.

Coping abilities in ALS/MND can now be measured using a simple 21 item self-report measure, offering two subscales with a focus of 'coping by self ' and 'coping with others'. This allows clinicians to identify individuals with poor coping and facilitates research on interventions that may improve coping skills.

Coping abilities in ALS/MND can now be measured using a simple 21 item self-report measure, offering two subscales with a focus of 'coping by self ' and 'coping with others'. This allows clinicians to identify individuals with poor coping and facilitates research on interventions that may improve coping skills.