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Lupus Vulgaris (LV) is the chronic, progressive, tissue destructive form of cutaneous tuberculosis. LV should be diagnosed and treated to prevent scaring and deformities. Histopathology is the gold standard for the diagnosis. Dermoscopy is helpful tool in diagnosing different dermatological condition. Here, dermoscopic and histopathogical correlation in LV was attempted.
It was a cross sectional, observational study done from February 2019 to October 2019. Nineteen patients of LV were included. Dermlite 4 with attached smart phone (iphone) was employed. LV lesions were subjected to skin biopsy to confirm the diagnosis.
Study enrolled 19 patients, with 8males, 5 female and 6 children. Dermoscopy showed yellowish-white globules, white structureless areas and white scales were noted in 19 (100%) patients. Telangiectasias were seen in 16 (84.21%) patients as long linear, branching and short linear vessels. Pinkish-red background was noted in all patients (100% n=19). Newer observations included white shiny streaks, white rosettes and bluish hue. Age, sex, duration of lesions had no influence in the dermoscopic patterns. Discrepancy in dermoscopic-histopathologic correlation was noted. https://www.selleckchem.com/products/at-406.html Facial lesions showed increased frequency of follicular plugs, patulous follicles and white rosettes.
Dermoscopy is widely gaining importance in the realm of dermatology. In this study, dermoscopy demonstrated characteristic patterns in LV. Thus, dermoscopy a non-invasive procedure can be used as diagnostic tool in many infective dermatoses.
Dermoscopy is widely gaining importance in the realm of dermatology. In this study, dermoscopy demonstrated characteristic patterns in LV. Thus, dermoscopy a non-invasive procedure can be used as diagnostic tool in many infective dermatoses.
The COVID-19 pandemic has disrupted clinical teaching in medical schools. Direct patient interaction, especially in groups, in out-patient departments or wards, was also made difficult. Institutes have adapted to the changed circumstances by increasing the use of online learning. We share our experience with a module of online Dermatology for undergraduate students.
An online module, aligned with the existing course objectives was designed and applied for two cohorts (year 4 and year 5). The module included student manuals, Powerpoint- presentations, videos, and quizzes uploaded on dedicated online management systems. There were live interactive sessions in small groups also. The small group session included student-led case presentations and faculty-led simulated case discussions. Feedback was taken from both the students and the faculty regarding the module using a structured questionnaire.
A total of 45 students and 4 faculty responded to the respective questionnaires. A majority of the students felt that the module covered the planned content adequately. The faculty and the majority of the students were also satisfied with the technical aspects of the module. Student and faculty concerns were mainly in the area of assessment and practical skills. While faculty were concerned about the validity of the assessment, students were concerned mainly about difficulty and the need for more orientation regarding the assessment.
The students and faculty were satisfied with the online Dermatology module in our study. However, the validity of assessment and the training of practical skills are major limitations.
The students and faculty were satisfied with the online Dermatology module in our study. However, the validity of assessment and the training of practical skills are major limitations.The aim of every academician and clinical dermatologist is to publish their research in reputed biomedical journals. But from conceptualization to completion, myriad shortcomings creep into the article and by the time it is ready for publication, by default and certainly not by design, the article discourse gets flawed, sometime fatally so. The endeavor of this article is to discuss these pitfalls from conceptualization, statistical machinations, authorial misconcepts, article structuring, and final journal selection. The article can function as a prophylactic checklist, albeit not comprehensive, by any prospective author and is an appreciation of the most oft repeated fallacies usually detected in publication submissions.
Surgical correction of scars may not be an ideal solution in all cases and hence it is desirable to have a nonsurgical option available. Autologous platelet-rich plasma (PRP) and fractional carbon dioxide laser (FCL) offer an alternative treatment modality.
To compare the efficacy and safety of FCL and intradermal PRP with FCL in the management of postburn and posttraumatic scars.
A prospective, randomized, observer-blinded, comparative study was conducted at a hospital skin centre from Oct 2016 to Sep 2018.
A total of 67 patients with scars were randomly divided into two groups; Group I was treated with four sessions of monthly FCL and Group II was treated with four sessions of PRP and FCL. The patients were assessed using the Patient and Observer Scar Assessment Scale (POSAS) at baseline and 4 weeks after each session.
For continuous variables, the summary statistics of mean ± standard deviation was used; for categorical data, number and percentage were used. Chi-square (χ2) test was used for association between two categorical variables.
value <0.05 was considered to be statistically significant.
Thirty cases in each group completed the study. There was a significant improvement in the total score of POSAS (p < 0.001) in both groups, but the final difference between the two groups was not statistically significant (p = 0.793 and
= 0.278, respectively).
Fractional CO2 laser causes significant improvement in scar appearance. PRP in combination with FCL offers no additional advantage.
Fractional CO2 laser causes significant improvement in scar appearance. PRP in combination with FCL offers no additional advantage.
Many factors have been implicated in the pathogenesis of atopic dermatitis (AD) and recently the role of oxidative damage has been postulated.
To study the levels of oxidants and antioxidants including melatonin in the blood of children with AD and their association with the severity of AD.
Thirty patients with atopic dermatitis, aged 6 months to 12 years, and equal number of age and sex-matched controls were included. Clinical characteristics and baseline severity assessment using SCORAD (scoring atopic dermatitis) severity index were noted. Blood superoxide dismutase, blood glutathione peroxidase, serum malondialdehyde, and serum melatonin levels were measured in cases and controls and results were compared.
The serum levels of malondialdehyde and melatonin were significantly higher among the cases compared to controls. The blood levels of superoxide dismutase and glutathione peroxidase were higher in cases but the difference with controls was not statistically significant. There was no significant correlation between these markers and the severity of the disease.
