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On one divide, energy types have been linked with the varying degree of environmental damage. Another perspective argued on the severity of the damaged base on per capita and/or population consumption pattern. As such, this study investigates the nexus of per capita natural gas consumption-carbon dioxide emissions and per capita income-carbon dioxide emissions in the case of the People of the Republic of China. This study objectively expanded to illustrate whether the N-shaped environmental Kuznets curve hypothesis holds in the case of China or not. The employed autoregressive distributed lag bound testing approach incorporated additional explanatory variables (urbanization) within the N-shaped EKC hypothesis over the period 1971-2018. Importantly, the results show an evidence of inverted N-shaped EKC relationship. In addition, the study posits a positive relationship between natural gas consumption and carbon dioxide emissions and between urbanization and carbon dioxide emissions. Thus, the study proposes renewable energy development and decongestion of the urban centers as a means of controlling global warming.The morphology and oxidation state of arsenic in its compounds affects the skin cell toxicity. Accordingly, the present study was conducted to explore the effects of two different arsenic compounds on the proliferation and survival of Liaoning cashmere goat skin fibroblasts. Based on MTT assay results, at 24 h, the proliferation concentration, critical concentration, and half inhibitory concentration (IC50) of sodium arsenite were 0.50, 5.00, and 45.66 μmol/L, respectively. The corresponding values for dimethyl arsenic acid were 0.85, 1.00, and 38.68 mmol/L. Immunofluorescence, transmission electron microscopy, and mitochondria membrane potential (MMP) assays showed that sodium arsenite promotes microtubule polymerization and increases MMP, while cells treated with dimethyl arsenic acid exhibited cytoskeletal collapse and decreased MMP. In the IC50 groups for both arsenic agents, the cytoskeletons collapsed, microtubules were gathered into bundles, and MMP was significantly decreased. mTOR inhibitor Dimethyl arsenic acid had a stronger effect on MMP than sodium arsenite. Flow cytometry revealed a slightly lower occurrence of apoptosis in the sodium arsenite proliferation group, while it was slightly increased in the dimethyl arsenic acid proliferation group. Apoptosis was increased more significantly in the sodium arsenite IC50 group than in the dimethyl arsenic acid IC50 group. These results indicate that the differences in cell proliferation and cytotoxicity induced by inorganic and organic arsenic are related to their effects on cellular structures.Hepatocellular carcinoma (HCC) is one of the ten most commonly diagnosed cancers. Doxorubicin is an antibiotic used in cancer treatment protocols that has several side effects. L-Arginine is a non-essential amino acid that is used as immune system activation and antitumor drugs. Therefore, the current study was designed to compare using doxorubicin, L-arginine, or their combination as a prophylactic agent against hepatic carcinoma induced by hepatocellular carcinoma cells (HepG2) injection in mice. The mice were divided into five groups normal mice and mice that received HepG2, doxorubicin and HepG2, L-arginine and HepG2, and doxorubicin, L-Arginine, and HepG2, respectively. Liver function test as, aspartate transaminase (AST) and alanine transaminase (ALT), and alpha-fetoprotein (AFP), caspase 3, interleukin 6 (IL-6), tumor necrotic factor (TNF), lipid peroxidation (NDA), and some antioxidant parameters were determined. A significant increase in AST and ALT, α-fetoprotein, TNF-α, and cytokines IL6 and MDA and a significant decrease in the serum caspase and liver catalase were determined in HepG2-injected mice. Moreover, some large hyperchromatic heptocytes were observed and the percentage of the positive area/field of HepPar-1, the most specific HCC marker, was 9.56%. Interestingly, mice that received doxorubicin, L-arginine, or their combination showed an improvement in some of the previous parameters. The improvement was more prominent with L-arginine administration.CO2 emissions are the leading causes of deterioration in air quality and global warming. Likewise, it has been shown that clean energy reduces air pollution, so this would be a way out of environmental pollution. Some previous studies have focused on knowing the determinants of environmental pollution; however, they have omitted the State's role. Thus, this study explores the long-term nexus between CO2 emissions and renewable energy, energy efficiency, fossil fuels, GDP, property rights from 1995 to 2019 in nine developed countries. The results reveal a long-term equilibrium relationship in developed European countries, but not in developed non-European countries. The main results show that renewable energy and energy efficiency are negatively correlated with CO2 emissions. In developed European countries, a 1% increase in renewable energy consumption represents a 0.03% decrease in CO2 emissions. Finally, some policy measures are suggested to achieve environmental sustainability.The aim of this study was to assess the impact of urban and industrial areas on an urban river through a comprehensive analysis of water and sediments. Six different sites along the San Luis River, Argentina, were characterized by measuring 12 physical-chemical parameters and nine heavy metals according to standard protocols. Metal pollution in sediment samples was evaluated with several indices. Cluster analysis was applied to standardized experimental data in order to study spatial variability. As, Cu, Cr, Mn, Pb, and Zn were the main contributors to sediment pollution, and the industrial zone studied showed moderate enrichment of Co, Cu, and Zn, probably due to anthropogenic activities. Cluster analysis allowed the grouping of the sites sediment samples were classified into two clusters according to the metal content; water samples were arranged into three groups according to organic matter content. The results were compared with sediment and water quality guidelines. They indicated progressive deterioration of water and sediment quality compared with the background area, mainly in the sites following the industrial park and domestic discharge areas.

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