Sutherlandpridgen7066

Vitamin C (VC) is widely used as an antioxidant and nutrient to increase the nutritional value and shelf-life of foods. In this article, VC was loaded in oleogels using a simple two-step emulsion-templated approach and the effects of oil type (linseed oil, corn oil, and camellia oil) and crystallization temperature (Tc, -18, 0, 5, and 25 °C) on the physical properties, VC concentration, and oxidation stability of the VC-loaded oleogels were studied. As the amount of saturated fatty acids in the oil phase of the oleogels decreased, the VC loading level, oxidation stability and physical properties of the corn-oil-based oleogel (COG) were better than those of camellia-oil-based oleogels and linseed-oil-based oleogels. At different Tc values, the temperature and frequency dependent storage modulus values for the COG crystallized at 0 °C and 5 °C were not significantly different (P > 0.05), but their values were higher than those for COG crystallized at -18 °C and 25 °C (P less then 0.05); the firmness of the COG crystallized at -18 °C and 0 °C was higher than those crystallized at 5 °C and 25 °C (P less then 0.05); the network of the COG crystallized at 0 °C was denser than those of the COG crystallized at -18 °C, 5 °C, and 25 °C; and the VC concentration of the oleogels was affected by the crystallization temperature (Tc) and temperature fluctuations. To sum up, a VC-loaded oleogel with excellent mechanical properties was prepared using corn oil and crystallized at 0 °C via an emulsion-templated approach.Correction for 'Rosetta custom score functions accurately predict ΔΔG of mutations at protein-protein interfaces using machine learning' by Sumant R. Empagliflozin Shringari et al., Chem. Commun., 2020, 56, 6774-6777, DOI .Molten salts are of great interest as alternative solvents, electrolytes, and heat transfer fluids in many emerging technologies. The macroscopic properties of molten salts are ultimately controlled by their structure and ion dynamics at the microscopic level and it is therefore vital to develop an understanding of these at the atomistic scale. Herein, we present high-energy X-ray scattering experiments combined with classical and ab initio molecular dynamics simulations to elucidate structural and dynamical correlations across the family of alkali-chlorides. Computed structure functions and transport properties are in reasonably good agreement with experiments providing confidence in our analysis of microscopic properties based on simulations. For these systems, we also survey different rate theory models of anion exchange dynamics in order to gain a more sophisticated understanding of the short-time correlations that are likely to influence transport properties such as conductivity. The anion exchange process occurs on the picoseconds time scale at 1100 K and the rate increases in the order KCl less then NaCl less then LiCl, which is in stark contrast to the ion pair dissociation trend in aqueous solutions. Consistent with the trend we observe for conductivity, the cationic size/mass, as well as other factors specific to each type of rate theory, appear to play important roles in the anion exchange rate trend.A methylenation-cyclization reaction, employing cyclic enaminones with primary aromatic amines and two molecules of CO2, furnishing fused-tetrahydropyrimidines, is discussed. In this Cs2CO3 and ZnI2 catalyzed one-pot two-step procedure, two molecules of CO2 were selectively converted to methylene groups. The multi-component reaction might proceed through the formation of bis(silyl)acetal which was followed by condensation and further aza-Diels-Alder reaction. Hydroquinazoline, hydrocyclopenta[d]pyrimidine and hydroindeno[1,2-d]pyrimidine derivatives could be prepared with CO2 as the C1 source, effectively.The catalyst assisted water-splitting method as an eco-friendly and cleaner pathway for energy generation has gained much interest in recent times. In this regard, numerous two-dimensional electrocatalysts such as mono/binary compounds synthesized from group IV, III-V and V elements with compatible activity towards hydrogen evolution, oxygen evolution, oxygen reduction and CO2 reduction have been reported. Motivated by the novel approach of material design and the need for better and cheaper electrocatalytic materials, we have investigated the ground state properties of the GeSb monolayer using state-of-the-art density functional theory. The computed electronic properties reveal the metallic nature of the pristine GeSb monolayer, indicating its potential for utilization as an electrocatalyst. The site-dependent catalytic response of the GeSb monolayer indicates that the Sb-site is more sensitive towards hydrogen adsorption amongst the considered sites. The computed adsorption and Gibbs free energies follow the trend of E less then E less then E. Finally, we have investigated the role of arsenic (As) and bismuth (Bi) doping on the catalytic activity of the GeSb monolayer. We notice that the electron density modulation occurs at the Sb-site due to incorporation of substitutional doping which results in a 72% enhancement in the catalytic activity of the monolayer on As substitution. The present study envisages that the electron density modulation can be utilized as a pathway for tailoring the catalytic activity of a system for the hydrogen evolution reaction.Enzymatic biofuel cells (EBFCs), as one of the most promising sustainable and green energy sources, have attracted significant interest. However, the limited lifetime and output power of EBFCs deriving from the intrinsic defects of natural enzyme fail to meet the requirements of commercial applications. As a robust approach, protein engineering shows promising potential to overcome these defects. In this review, we will elaborate on the basic principles, structure and electron transfer pathways of EBFCs, and discuss the strategies of protein engineering for improving the performances of EBFCs. We hope that this review will inspire researchers to envisage efficient enzymes for EBFCs and promote the commercial transformation of EBFCs in implantable medical devices, portable power batteries and even clean-power-driven cars in the near future.The syntheses, structures and magnetic properties of a series of dimeric dysprosium(iii) complexes [Dy2L2(CH3OH)(H2O)]·2X·solvent X = Cl (1), NO3 (2), ClO4 (3) and [Dy2L2(CH3OH)2]·2X·solvent X = CF3SO3 (4), formed from the 1  1 reactions of the H2L ligand with the corresponding dysprosium salts, are reported. Structural and magnetic studies reveal that counter anions on the periphery play a significant role in determining the dynamic magnetic relaxation process of these complexes. The coordination geometries of the Dy(1)(iii) centers are eight-coordinate triangular dodecahedra in 1-4. All compounds exhibit single-molecule magnet (SMM) behavior under a zero dc field and optimal applied dc field except 3, which displays only slow relaxation of magnetization. A comparison of the magnetic properties and structural parameters of the four compounds shows that the short Dy-Ophen distances and the large Ophen-Dy-Ophen angles create an axial ligand field in which dysprosium(iii) complexes exhibit magnetic anisotropy and SMM properties.

Recent increase in demand for starch in food applications has called for research into other new sources. Dioscorea villosa is an underutilized wild yam starch source and its starch was isolated and succinylated at 0, 3, 6, 9 and 12% (0-12% succinic anhydride 88-100% starch) using standard procedures. The degree of substitution, chemical composition, functional properties, anti-nutritional factors, pasting properties, atomic spectra and α-amylase and α-glucosidase activities of the samples were determined using standard methods. The data obtained were analysed using ANOVA.

The percentage succinyl content and degree of substitution increased from 0-10.45% and 0-0.19% respectively. The amylose, amylopectin, α-amylase and α-glucosidase activities varied from 49.88-59.70%, 40.29-50.11%, 0.17-0.96 and 0.62-10.07 respectively. The phytate, tannin, oxalate and saponin contents ranged from 0.08-0.13 mg g-1, 0.04-0.08 mg g-1, 0.21-0.31 mg g-1 and 0.18-0.26 mg g-1 respectively. The peak viscosity, trough, break dowsirable in the production of slowly digestible food products, such as snacks for diabetic patients.Four structurally distinct classes of polypyridyl ruthenium complexes containing avobenzone exhibited low micromolar and submicromolar potencies in cancer cells, and were up to 273-fold more active than the parent ligand. Visible light irradiation enhanced the cytotoxicity of some complexes, making them promising candidates for combined chemo-photodynamic therapy.The diversity and activity of the gut microbiota residing in humans and animals are significantly influenced by the diet. Quercetin, one of the representative polyphenols in human diets, possesses a wide range of biological properties. The aim of this study was to investigate the prebiotic effects of quercetin in antibiotic-treated mice. Gut dysbiosis was successfully induced in mice by treatment with an antibiotic cocktail. Gas chromatography and 16S rDNA high-throughput sequencing techniques were used to investigate short-chain fatty acid content and gut microbial diversity and composition. The results showed that quercetin supplementation significantly improved the diversity of the gut bacterial community in antibiotic-treated mice (P less then 0.05). Meanwhile, intestinal barrier function was also recovered remarkably as indicated by a decrease in the content of serum d-lactic acid and the activity of serum diamine oxidase (P less then 0.05). The length of intestinal villi and mucosal thickness were also significantly increased in response to quercetin treatment (P less then 0.05). Furthermore, the production of butyrate in faeces was enhanced significantly in quercetin-treated mice (P less then 0.05). In conclusion, quercetin is effective in recovering gut microbiota in mice after antibiotic treatment and may act as a prebiotic in combatting gut dysbiosis.A novel strategy, composed of epoxy-resin filling, carbonization, and hydrothermal growing of NiCo2S4 nanorods, was developed to enlarge the surface area of nickel foam (NF) for loading electrochemically active materials and to successfully fabricate NiCo2S4/carbon-filled NF binder-free electrodes. Due to the certain electrical conductivity of the filled epoxy-resin-derived carbon and the enlarged loading surface area, the targeted electrode possesses outstanding electrochemical energy storage performance, with a maximum specific capacitance of 9.28 F cm-2 at a current density of 4 mA cm-2, more than 6 times the 1.46 F cm-2 of the NF-based electrode formed via directly growing NiCo2S4 on NF, and with a specific capacitance retention of about 60% after 2000 charge/discharge cycles. Our strategy provides a promising avenue for constructing a high-performance NF-based binder-free electrode and our resultant electrode presents great application potential in electrochemical energy storage.New dipyridylpyrrole N-oxide ligands HL1 and HL2 are designed and synthesized via oxidation of 2-(5-(pyridin-2-yl)-1H-pyrrol-2-yl)pyridine (Hdpp) by using 3-chloroperbenzoic acid (m-CPBA) in CH2Cl2. The treatment of ZnEt2 with two equiv. of HL1 and HL2 affords [Zn(L1)2] and [Zn(L2)2] in medium yield, respectively. These ligands and zinc complexes are fully characterized by NMR, IR, UV-vis and ESI-MS spectroscopy and X-ray diffraction analysis. The structure of HL1 and HL2 shows a planar geometry. The intramolecular hydrogen-bond interactions between the imino hydrogen and N-oxide oxygen atom are observed. In [Zn(L1)2] and [Zn(L2)2], two ligands chelate to the zinc metal with a cross perpendicular geometry. The zinc complexes were employed as a highly efficient catalyst for the thiol-Michael addition of thiols to α,β-unsaturated ketones in EtOH at room temperature. The loading of the catalyst is lowered to 0.01 mol%. The catalytic mechanism was proposed based on NMR and ESI-MS experiments.