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The enhanced quality of fermented mulberry wine showed contraindications with decreased constituents and escalated wine quality. Rather than usual single inoculum, fermentation combination of LAB and yeast holistically influenced the color, taste, fragrance, phenolic profiles, and antioxidant properties in mulberry wine, ensuring palatability and fit for commercialization prospects.Aflatoxin M1 is the most significant toxin of milk and milk products. It is immunosuppressive, mutagenic, and carcinogenic compounds to humans. Therefore, this study was aimed to evaluate the concentration of aflatoxin M1 and its determinants in raw cow milk sample intended for human consumption in South Gondar Zone, Ethiopia. A cross-sectional study was conducted on a total of 100 dairy farmers from January to February 2020. Around 50 ml, 100 raw milk samples were collected for aflatoxin M1 analysis. A simple random sampling technique was applied to get the households. Binary and multivariate logistic regressions were used to see the association between predictor and outcome variables. From the 100 dairy farmers who had participated, 38% had heard about aflatoxin in the milk sample. Aflatoxin M1 was detected in the 99(99%) raw milk samples, of these 41 (41%) exceeded the limit of the European Union. The logistic regression analysis result showed that residence, awareness about the level of aflatoxin in the milk sample, management mold-contaminated animal feed, animal feed storage facility, and grazing systems were significantly associated with the high level of aflatoxin in the milk sample. Almost all milk samples analyzed were positive for aflatoxin M1, and 41% of samples were above the limit set by European Union. Many easily manageable and preventable factors were associated with higher levels of aflatoxin M1 in the milk sample than the European Union limit, which suggests continuous monitoring of milk and milk products is necessary.Micronutrient deficiencies in low-income countries are associated with the monotonous consumption of nutrient-deficient crops, contributing to childhood stunting with far-reaching socioeconomic consequences. To promote nutrition sensitive agriculture, policy makers in such countries have embarked on policy initiatives that encourage agricultural diversification in smallholder farming systems. This paper investigates the link between agricultural diversification and two key indicators of food and nutrition security among children under 5 years in rural Zambia. Data from the 2015 Rural Agricultural Livelihoods Survey and regression models are used to explain household dietary diversity and months of inadequate household food provisioning among 7934 households. Factors associated with the key outcome variables include land cultivated, household size, total livestock units, household head education, households receiving extension information, and use of productivity-enhancing inputs such as fertilizers. Although the results demonstrate that agricultural diversification is positively associated with the household dietary diversity score, the relationship is not statistically significant. Further, the study findings illustrate that agricultural diversity is negatively associated with months of inadequate household food provisioning but that this relationship is also not statistically significant. The implication for policy is that other interventions such as productivity enhancement and behavioral change communication need to be scaled up.Doxorubicin (DOX) is an anthracycline antibiotic used in the clinical treatment of cancer, but its use is limited due to its cardiotoxic effects. Therefore, it is necessary to explore natural compounds that are effective in protecting against the cardiotoxicity caused by DOX. Neutral Morchella conica polysaccharides-2 (NMCP-2) is a natural polysaccharide with antioxidant activity that was isolated and purified from Morchella conica in our laboratory's previous study. This study aimed to investigate the possible protective effect of NMCP-2 on DOX-induced cardiotoxicity and the potential underlying mechanisms. The model of DOX-induced H9C2 cells and the model of DOX-induced mice were used in this study. In in vitro studies of H9C2 myocardial cells, NMCP-2 effectively increased the activity of H9C2 cells, reducing the levels of lactate dehydrogenase (LDH). In the mouse model of DOX-induced chronic cardiotoxicity, NMCP-2 significantly reduced the cardiac index, reduced the release of serum cardiac enzymes, and improved the pathology of murine myocardial tissues, thereby alleviating DOX-induced cardiotoxicity. Further mechanism studies showed that pretreatment with NMCP-2 counteracted the oxidative stress induced by DOX, as indicated by increasing superoxide dismutase (SOD), catalase (CAT), glutathione (GSH) activities, and malondialdehyde (MDA) production decreased. In addition, we observed NMCP-2 inhibited the activation of the mitochondrial apoptosis pathway and regulated the disordered expression of Bcl-2 and Bax in the myocardial tissues of DOX-treated mice. These findings indicated that NMCP-2, a natural bioactive compound, could potentially be used as a food supplement to reduce the cardiotoxicity caused by DOX.Poor sleep quality can lead to increased obesity. Low carbohydrate diet (LCD) is considered as an approach for sleep quality and obesity improvement. The aim of this investigation is to evaluate the relationship between LCD and sleep quality with the mediatory effect of inflammatory markers including transforming growth factor-β (TGF-β), high-sensitivity C-reactive protein (hs-CRP), total antioxidant capacity In our cross-sectional study, 304 obese women aged from 19 to 50 years were enrolled. Body mass index (BMI) in these women ranged from 25.2 to 48.3 kg/m2. LCD score was assessed by a 147- item semi-quantitative food frequency questionnaire (FFQ). The Pittsburgh Sleep Quality Index (PSQI) was used to assess the sleep quality. FFQ and PSQI questionnaires are completed simultaneously by the participants. Biochemical indicators (inflammatory markers) were measured and anthropometric components were evaluated. The relationship between sleep quality and LCD with quantitative variables was assessed by independent sample t-test and with qualitative variables by chi-square test. Binary logistic regression was used to estimate confounding variables including age, job, stress, weight to investigate the relationship between LCD and sleep. Following of LCD had a significant negative relationship with PSQI score. It can be said that with increasing LCD adherence, the possibility of poor sleep quality decrease (OR = 0.43, 95% CI = 0.19-0.94,p = .03). It was also showed, hs-CRP (OR = 0.61, 95% CI = 0.3-1.21, p = .16) and TAC (OR = 0.6, 95% CI = 0.25-1.4, p = 0.24), eliminated the significance of the association and it is possible that they play a mediating role in this relationship Following the LCD can have a positive effect on improving PSQI scores by reduction in inflammatory markers levels.The oil uptake and high-fat/oil content problem associated with fried food products can be decreased using polysaccharides (mucilages and gums) as edible coatings. learn more In this study, the efficiency of seeds mucilages (Balangu, Basil, and Wild sage), and xanthan gum as edible coatings on the oil uptake, moisture retention, and physical properties (color indexes and surface shrinkage) of potato strips during oil frying have been examined. Coating treatment with seeds mucilages and xanthan gum significantly decreased the moisture loss and oil uptake of potato strips (p less then .05). Lightness (L*) index values of uncoated-control and coated potato strips decreased during frying. The lowest and highest color change intensity (∆E) and surface shrinkage (%) values were observed for the potato strips coated by Wild sage seeds gum and uncoated-control sample, respectively. The MMF (Morgan-Mercer-Flodin) model was selected as the best equation for describing the color changes intensity kinetics of untreated and treated potato strips during frying. The appropriate coating suspension for reducing the oil content of fried potato strips and improving product appearance quality was 1.0% Wild sage seeds gum.Previous study has suggested the colonic nontoxicity and obesity inhibition of food-grade κ-carrageenan in obese mice. Further study using transcriptome is important to provide further understanding on the gene expressions of inflammation and obesity. Here, the obese mice without any treatment (HFD) or with 5% food-grade κ-carrageenan diet intervention (H5%) were used to perform colonic transcriptome sequencing. The results showed that genes involved in the inflammatory pathways or tight junction protein encoding were not significantly dysregulated by 5% carrageenan. However, the expression of lipid metabolism genes meaningfully changed as evidenced by the decreased gene levels of adipocytokines, lipogenesis, lipid absorption and transport, and the increased adipolysis and oxidation. In addition, the carrageenan metabolism experiments by toluidine blue (TB) staining of colon and high-performance size exclusion chromatography (HPSEC) of feces supernatant showed that the food-grade κ-carrageenan was not absorbed or significantly degraded in the digestive tract of obese mice. Hence, the fact that food-grade κ-carrageenan was not significantly metabolized by the organism and did not cause obvious dysregulation of colonic inflammatory genes provided evidences for its noncolonic toxicity in obese mice. An anti-obesity potential of food-grade κ-carrageenan was probably mediated by the regulation of lipids metabolism-related genes.

Food neophobia was defined as the unwillingness or avoidance to eat new foods. There are many studies on food neophobia in children, but few in university students. This study was to examine the level of food neophobia of Chinese university students. The aim is to find a way to help them relieve food neophobia.

A total of 2,366 university students (16-22years old) from Xinyang normal university were recruited to conduct a questionnaire survey on food neophobia scale (FNS) of Chinese version, which contained 10 questions. Significant difference analysis and principal component analysis were conducted.

For Chinese university students, willingness to try new food, trust in new food, eating disorder, and food pickiness were the characteristic indexes to evaluate the food neophobia. Gender had no significant effect, but long-term nutrition courses had a great impact on food neophobia of university students.

The level of food neophobia of Chinese university students is relatively high. To formulate and implement a continuous diet and nutrition education plan is good and necessary to relieve the food neophobia.

These data complement the limited literature on food neophobia of university students, which will help to develop intervention plans to reduce eating disorders and support the need for further research to reveal the potential mechanism.

These data complement the limited literature on food neophobia of university students, which will help to develop intervention plans to reduce eating disorders and support the need for further research to reveal the potential mechanism.

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