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Most theories of emotion describe a crucial role for interoceptive accuracy, the perception of the body's internal physiological signals, in emotional experience. Despite support for interoceptive accuracy's role in emotion, findings of gender differences in emotional and interoceptive processing are incompatible with theory; women typically show poorer interoceptive accuracy, but women often outperform men on measures of emotional processing and recognition. This suggests a need to re-evaluate the relationship between interoceptive accuracy and emotion considering sex and gender. Here we extend Pennebaker and Roberts' (1992) theory of gender differences in the use of interoceptive signals for emotional experience, proposing that language socialisation may result in gender differences in the propensity to label internal state changes as physiological or emotional, respectively. Despite outstanding questions concerning the fractionation of interoceptive and emotional domains, this theory provides a plausible explanation for seemingly incompatible findings of gender differences in interoceptive and emotional abilities.Turing inspired a computer metaphor of the mind and brain that has been handy and has spawned decades of empirical investigation, but he did much more and offered behavioral and cognitive sciences another metaphor-that of the cascade. The time has come to confront Turing's cascading instability, which suggests a geometrical framework driven by power laws and can be studied using multifractal formalism and multiscale probability density function analysis. Here, we review a rapidly growing body of scientific investigations revealing signatures of cascade instability and their consequences for a perceiving, acting, and thinking organism. We review work related to executive functioning (planning to act), postural control (bodily poise for turning plans into action), and effortful perception (action to gather information in a single modality and action to blend multimodal information). We also review findings on neuronal avalanches in the brain, specifically about neural participation in body-wide cascades. Turing's cascade instability blends the mind, brain, and behavior across space and time scales and provides an alternative to the dominant computer metaphor.

Definitive chemoradiotherapy (CRT) is the standard treatment for patients with locally advanced esophageal cancer (EC) who refuse surgery as the initial therapy. However, poor survival, a high incidence of late toxicities, and severe complications after salvage surgery remain issues to be resolved. This single-arm multicenter trial (JCOG0909) aimed to confirm the efficacy of CRT modifications, including salvage treatment for reducing CRT-related toxicities and facilitating salvage treatment for improved survival.

Patients with clinical stage II/III EC (International Union Against Cancer sixth edition, non-T4) were eligible. Chemotherapy comprised cisplatin (75 mg/m

on days 1 and 29) and 5-fluorouracil (1000 mg/m

/d on days 1-4 and 29-32). Radiation therapy was administered at a total dose of 50.4 Gy. Good responders received 1 to 2 additional cycles of chemotherapy. For residual or recurrent disease, salvage endoscopic resection or salvage surgery was performed based on specific criteria. The primary eties and yields good OS, thus making it a promising novel treatment option for patients with locally advanced EC.Fairness is a remarkable preference for human society, involving both outcome and opportunity equity. Most previous studies have explored whether fairness itself or self-interest is intuitive during outcome (in)equity. However, intuition during outcome (in)equity can be affected by both fairness level and actual payoff. Since opportunity (in)equity is only affected by the fairness level, we explored only intuition during fairness by measuring event-related potential responses to opportunity (in)equity. Participants played a social non-competitive two-person choice game with advantage opportunity inequity (AI), opportunity equity (OE), and disadvantage opportunity inequity (DI). The behavioral results suggested an opportunity inequity bias, with greater feelings of fairness and pleasantness during OE than during AI and DI. However, multivariate pattern analysis of the event-related potential (ERP) data suggested that AI, OE, and DI can be significantly distinguished from each other in relatively early windows overlapping with early positive negativity (EPN), and AI and DI can be significantly further distinguished during a relatively late window overlapping with late positive potential (LPP). Moreover, the conventional ERP analysis found that EPN amplitudes were more negative for AI than for OE and DI, as well as for OE than for DI, suggesting a pleasure bias for increased self-interest. LPP amplitudes were greater for DI than for AI and OE, suggesting enhanced sensitivity to DI. MC3 in vitro These results suggest that self-interest is intuitive during opportunity (in)equity.Waste activated sludge (WAS) has low biodegradability that restricts acidogenic fermentation (AF), thereby limiting the high-value volatile fatty acids (VFAs) production. This study investigated an alternative electrochemical pretreatment (EPT) approach that can facilitate AF of WAS and food waste (FW) and therefore enhance VFAs production. The results showed through introducing 50 % volatile solid basis of FW (containing massive chloride) into WAS, a 60-min EPT produced reactive chlorine species (RCS), which diffused into WAS-FW inner layers resulting in cell lysis, therefore significantly promoted and accelerated WAS-FW disintegration, contributing to more soluble and biodegradable dissolved organic matter (DOM). Then during the subsequent 15-day acidogenic co-fermentation (Co-AF), the residual RCS (approximate 5 mg Cl2/L) also caused acidogenic bacteria (including Prevotella_7, Lactobacillus and Veillonella) gradually outcompeted methanogens due to their different tolerance to residual RCS. Consequently, the maximum VFAs yield of the WAS-FW Co-AF with EPT was 40.8 % higher than WAS-AF without EPT.Constructed wetlands (CWs) are widely considered as resilient systems able to adapt to environmental perturbations. Little attention has been paid, however, to microbial dynamics when CWs withstand and recover from external shock. To understand the resilience of CWs, this study investigated rhizosphere microbial dynamics when CWs were subjected to influent COD perturbation (200 mg/L-1600 mg/L). Results demonstrated that CWs had strong adaptability to different influent perturbations, characterized by transitions from fluctuating to stable pollutant removal. Microbial analysis showed that rhizosphere microorganisms competed for niches in response to increased COD concentrations, and Trichococcus played key roles in resisting concentration perturbations. Structural equation modeling indicated that rhizosphere community succession and microbial energy metabolism were shaped by pH and DO. These findings provide insights into the mechanism for CW stability maintenance when facing concentration perturbations.Biomass gasification is recognized as a viable avenue to accelerate the sustainable production of hydrogen. In this work, a numerical simulation model of air gasification of rice husks is developed using the Aspen Plus to investigate the feasibility of producing hydrogen-rich syngas. The model is experimentally validated with rice husk gasification results and other published studies. The influence of temperature and equivalence ratio on the syngas composition, H2 yield, LHVSyngas, H2/CO ratio, CGE, and PCG was studied. Furthermore, the synchronized effects of temperature and ER are studied using RSM to determine the operational point of maximizing H2 yield and PCG. The RSM analysis results show optimum performance at temperatures between 820 °C and 1090 °C and ER in the range of 0.06-0.10. The findings show that optimal operating conditions of the gasification system can be achieved at a more refined precision through simulations coupled with advanced optimization techniques.Bio-utilization of lignocellulosic biomass is of huge significance as it can directly replace petroleum resources by producing liquid fuels and organic chemical products in a more sustainable way. However, studies on developing lignin-degrading microbial resources are still very few, which affects on establishing a consolidated bioprocessing of lignocellulosic resource. The main aim of this work is to discover thermostable laccases for lignin thermo-biodegradation by metagenome-mining and biochemical characterization. Results indicate that 124 putative thermostable laccase genes were identified from generated metagenomes. Significantly, 3 rationally selected proteins showed actual activity and structural stability at temperatures up to 60 °C and pH values as low as 4.87. These active recombinant enzymes verify a practical advance in the functional prediction of target proteins, and simultaneous sequence-to-function relationships in this metagenome. In short, the identified thermostable laccase genes in this work could expand range of lignin biocatalysts and contribute to build an efficient lignin biorefinery.The method of collecting microalgae using fungal mycelium pellets has attracted widespread attention because of its high efficiency and simplicity. In this study, the interaction in FMSS was explored using Aspergillus fumigatus and Synechocystis sp. PCC6803. Under the conditions of 25-30 °C, pH of 5.0, 160 rpm, a light intensity of 1000 lx, light to darkness ratio of 618 h, and glucose concentration of 1.5 g/L, the FMSS had the highest biomass and recovery efficiency. SEM, TEM, and Zeta analysis showed that microalgae can be fixed on the surface of fungal mycelium pellets by the electrostatic attraction (amino, amide, phosphate, hydroxyl, and aldehyde groups) of EPS. The N cycling and CO2-O2 cycling promoted the synthesis of amino acids and provided a guarantee for gas exchange, and the intermediate metabolites (CO32- and HCO3-/H2CO3) satisfied the metabolic activities. The microalgae and fungi worked in coordination each other, which was the mutualistic symbiosis.The present study reports a strategy to produce polyhydroxyalkanoates (PHAs) by culturing the marine bacterium Rhodovulum sulfidophilum DSM-1374. The study was carried out by growing the bacterium anaerobically for 720 h under 16/8 light/dark cycle. Two analytical techniques such as proton magnetic nuclear magnetic resonance (1H NMR) and Fourier transform infrared spectroscopy (FT-IR) were used to determine that the polyester produced was poly-3-hydroxybutirate-co-3-hydroxyvalerate (PHBV). This study showed that the excess of lactate and the limitation of N-P nutrients under a light-dark cycle enhanced PHBV synthesis and achieved a PHBV concentration of 330 mg/L in the R. sulfidophilum culture. During the 30 days of bacterial cultivation, the percentage of polymer in the six harvested dry biomasses gradually increased from 13.7% to 23.4%. In addition, the study showed that PHBV synthesis stopped during the 8-h dark phase and restarted in the light. The light-dark cycle study also showed that R. sulfidophilum DSM-1374 can be grown outdoors because the cells are exposed to the natural light-dark cycle.