Stormweiss9002

The aquatic bacterial community (BC) plays a vital role in determining the nature and rate of ecosystem function. However, the biotic and abiotic factors influencing BC structure and function are largely unknown. Hence, the current study characterizes the impact of biotic and abiotic factors on aquatic bacterial biodiversity to determine whether the dominant effects are biotic or abiotic by partitioning their relative effects across temperate Canadian lakes. We collected water samples from sixty southern Ontario lakes and characterized their BC and microbial eukaryotic community (MEC) compositions using high throughput metabarcode sequencing of 16S and 18S rRNA gene fragments. The diversity and richness of aquatic BCs differed considerably among our study lakes, and those differences were explained by environmental, spatial, and biotic (MEC) factors (31%, 23%, and 23% of variance explained, respectively). The relatively large contribution from biotic and abiotic factors (54%), relative to spatial effects, shows deterministic processes prevail in shaping BC assembly in freshwater lakes. However, spatial effects also contributed significantly, highlighting the role of stochastic processes (ecological drift and coupled with limited dispersal) in shaping BC structure. Furthermore, our co-occurrence network analysis showed strong positive and negative interactions within and between the BCs and MECs, indicating mutualistic or antagonistic co-occurrence patterns relationships play important roles in driving the variation in BC composition among our sampled lakes. Considered together, our community analyses show that deterministic and stochastic processes combined contribute to determining the aquatic BC composition, and hence likely function as well, across a broad array of temperate freshwater lakes.Central Asia (CA) is a core area of global desertification, but the effect of the intensifying "global greening" policy on the desertification process under global warming scenarios in CA remains unclear. Based on multi-source remote sensing data and Inter-Sectoral Impact Model Intercomparison Project (ISIMIP) 2b climate data, this study investigated desertification in CA using actual evapotranspiration (ETa), temperature and precipitation as driving factors. Coupling with the CA-Markov model, the inversion method of desertification was improved, and the evolution normal form of desertification in CA was proposed. Finally, spatio-temporal variations of desertification in CA were quantified. The results indicate that temperature, precipitation, and normalized difference vegetation index (NDVI) in CA increased during the historical period (1980-2015), with sudden changes in 1994. In contrast, although ETa exhibited fluctuating increases (7.41 mm/10 yr) during this period, no sudden changes were observed in 1994. In the future (2006-2099), the climate of CA will become warmer and wetter. With reference to 1980-2005, precipitation under global warming of 2.0 °C (GW2.0) will be higher than that under global warming of 1.5 °C (GW1.5) by 10.3 mm, and ETa will increase by 20.88 mm and 27.54 mm under GW1.5 and GW2.0, respectively. Although the area of desert lands has decreased (5.94 × 104 km2/10 yr), the area of potential desert lands has increased (0.17 × 104 km2/10 yr). With global warming, this situation will continue to intensify, mainly in Xinjiang of China, and Kazakhstan. The Aral Sea plays an important role in the desertification of CA. The potential increase in desert land under GW2.0 is equivalent to the current water area of the Aral Sea. The findings could provide policy support for combating desertification in CA and promoting the achievement of the Sustainable Development Goals.

The prevalence of pollen allergy has increased due to urbanization, climate change and air pollution. The effects of green space and air pollution on respiratory health of pollen allergy patients are complex and best studied in spatio-temporal detail.

We tracked 144 adults sensitized to Betulaceae pollen during the tree pollen season (January-May) of 2017 and 2018 and assessed their spatio-temporal exposure to green space, allergenic trees, air pollutants and birch pollen. Participants reported daily symptom severity scores. We extracted 404 case days with high symptom severity scores and matched these to 404 control days. The data were analyzed using conditional logistic regression with a 11 case-crossover design.

Case days were associated with exposure to birch pollen concentration (100 grains/m

) [adjusted odds ratio 1.045 and 95% confidence interval (1.014-1.078)], O

concentration (10 μg/m

) [1.504 (1.281-1.766)] and PM

concentration (10 μg/m

) [1.255 (1.007-1.565)] on the day of the severe allergy event and with the cumulative exposure of one and two days before. Exposure to grass cover (10% area fraction) [0.655 (0.446-0.960)], forest cover (10% area fraction) [0.543 (0.303-0.973)] and density of Alnus (10%) [0.622 (0.411-0.942)] were protective for severe allergy, but only on the day of the severe allergy event. Increased densities of Betula trees (10%) were a risk factor [unadjusted OR 2.014 (1.162-3.490)].

Exposure to green space may mitigate tree pollen allergy symptom severity but only when the density of allergenic trees is low. Air pollutants contribute to more severe allergy symptoms. Spatio-temporal tracking allows for a more realistic exposure assessment.

Exposure to green space may mitigate tree pollen allergy symptom severity but only when the density of allergenic trees is low. Air pollutants contribute to more severe allergy symptoms. Spatio-temporal tracking allows for a more realistic exposure assessment.Maintaining and expanding protected areas (PAs) can benefit humans and the rest of nature, but also has direct management and opportunity costs. Assessing this trade-off can benefit from valuing ecosystem services (ESs). The gross value of a subset of ESs provided by China's existing terrestrial PAs, which cover 18% of China's land, was conservatively estimated at $2.64 trillion/yr (US$2017). This is 15 and 14 times the basic conservation costs (for preventing current ESs and biodiversity from deteriorating) and optimised conservation costs (for potentially improving ESs and biodiversity), respectively. China is committed to drawing an 'eco-redline' (the natural terrestrial space that has important ESs, biodiversity, vulnerable and sensitive ecosystems, and enforced strict conservation) to protect 25% of its lands. If the 'eco-redline' was to conserve 25% of China's terrestrial water retention, soil retention, sandstorm prevention, carbon sequestration and oxygen release, the gross value of those conserved regulating ESs would be $4.83 trillion/yr. This is 20 and 18 times the basic and optimised conservation costs, respectively. These results indicate that, the arguments that conservation constrains economic development and increases ecosystem disservices are not tenable. The results make clear the interconnections between conservation and the economy, and that true economic development is improvement of sustainable wellbeing - not merely growth of Gross Domestic Product (GDP).The prevalence of antibiotic residues and antibiotic-resistant Escherichia coli (ARE) in closed (CSF) and open (OSF) pig farming systems was analysed. Results showed that a high level of E. coli populations, antibiotic contamination in supplied water, and additional antibiotics used, such as neomycin (NEO) or colistin (CLT), were observed in OSF. Similar ARE resistance to five antibiotics, including NEO, was observed in the water source, dung, and wastewater/sludge but were different from those of CLT. An increased occurrence of ARE was found in the sludge of anaerobic digestion (AD) and the waste stabilisation pond (WSP), but they were not well correlated with their residual antibiotic concentrations. Histone Methyltransferase inhibitor CLT administration yielded higher ARE prevalence in pig excreta and wastewater in OSF, but its absence in CSF also resulted in ARE occurrence with increased minimal inhibitory concentration (MIC) levels in the anaerobic digester/waste stabilisation ponds. This study revealed that ARE prevalence and MIC levels of CLT could be developed during the wastewater treatment process in the pig farm, although none of the AREs were found in the original excreta/wastewater.The safe utilization of solid wastes containing heavy metals plays a crucial role in environmental preservation. As an efficient technology to achieve this goal, the preparation of glass ceramic foams from solid wastes can produce an excellent solidification effect on heavy metals. At present, there have been plenty of efforts made to achieve an excellent combination of such characteristics as mechanical strength, bulk density, thermal conductivity and so on, with the purpose to ensure the application in various high value-added fields. Due to the concentration on their application in the construction sector such as the use of thermal and acoustic insulation materials, some researchers seek to expand the scope of their applications. In this paper, a review is conducted into the methods used to prepare solid waste-based glass ceramic foams. Depending on the exact processing route, these methods can be categorized into two classes, which are powder sintering and inorganic gel casting. Not only heavy metals hinder the application of solid waste, they can also cause irreversible pollution to the wider environment. Solidification and volatilization represent the two routes associated with heavy-metal migration during the preparation of glass ceramic foams. Both traditional and innovative applications are indicated in this review. Furthermore, a discussion is conducted about the prospects and challenges facing different processing strategies, heavy-metal migration and applications.DAPT (N-[N-(3, 5-difluorophenacetyl)-l-alanyl]-s-phenylglycinet-butyl ester) is a γ-secretase inhibitor that indirectly blocks the activity of Notch pathway. It is a potential therapeutic target drug for many diseases, such as cancer, neurological, cardiovascular, and cerebrovascular diseases. However, the pharmacological action and specific mechanisms of DAPT are not clear. Planarians have strong regenerative capacity and can regenerate a new individual with a complete nervous system in one week. Thus, they are used as an ideal indicator of environmental toxicants and a novel model for studying neurodevelopmental toxicology. In this study, different concentrations and treatment times of DAPT are used to analyze the gene expression levels of major components in Notch pathway. The results show that the optimal concentration and exposure time of DAPT is 100 nM for 10 days in planarians and indicate that the inhibitory of DAPT treatment on Notch pathway is time- and concentration-dependent. The potential impact of DAPT is effectively analyzed by qPCR, WISH, and Immunofluorescence. The results indicate that DAPT exposure causes intact planarian wavy or swollen, and regenerative planarians asymmetric growth or muti-eye. Moreover, DAPT exposure increases cell proliferation and apoptosis, results in neurodevelopmental defects and dynamic changes of some marker genes. These results suggest that the balance of proliferation and apoptosis is disturbed, and then, affecting tissue homeostasis and differentiation. These findings demonstrate that DAPT has serious side effects in organisms and relies on Notch pathway to determine cell fate, it is cautious in the use of DAPT as a potential therapeutic approach for the disease in clinical trials.