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Significant differences were also not observed in the analysis of muscle fibers and connective tissue.

Exposure to 0.5% glyphosate during pregnancy and lactation resulted in lower weight gain during pregnancy, final weight, and naso-anal length. Despite not directly altering the morphology of muscle tissue, these results may indicate enough exposure to interfere with animal metabolism.

Exposure to 0.5% glyphosate during pregnancy and lactation resulted in lower weight gain during pregnancy, final weight, and naso-anal length. Despite not directly altering the morphology of muscle tissue, these results may indicate enough exposure to interfere with animal metabolism.

The intensity of the thromboprophylaxis needed as a potential factor for preventing inpatient mortality due to coronavirus disease-19 (COVID-19) remains unclear.

To explore the association between anticoagulation intensity and COVID-19 survival.

Retrospective observational study in a tertiary-level hospital in Spain.

Low-molecular-weight heparin (LMWH) status was ascertained based on prescription at admission. To control for immortal time bias, anticoagulant use was analyzed as a time-dependent variable.

690 patients were included (median age, 72 years). LMWH was administered to 615 patients, starting from hospital admission (89.1%). 410 (66.7%) received prophylactic-dose LMWH; 120 (19.5%), therapeutic-dose LMWH; and another 85 (13.8%) who presented respiratory failure, high D-dimer levels (> 3 mg/l) and non-worsening of inflammation markers received prophylaxis of intermediate-dose LMWH. The overall inpatient-mortality rate was 38.5%. The anticoagulant nonuser group presented higher mortality rifit of heparin within different therapeutic regimes for COVID-19 patients are required.

Gastritis consists of inflammation of the gastric mucosa and is one of the main causes of dyspeptic symptoms in children.

To investigate the presence of inflammation by evaluating fecal calprotectin (FC) in children diagnosed with chronic gastritis.

Descriptive study in Pediatric Gastroenterology Department of Ondokuz Mayis University Hospital in Turkey.

Between January 2016 and July 2018, FC levels were compared retrospectively in children with chronic gastritis (histopathology-based diagnosis), patients with inflammatory bowel disease (IBD) and healthy children.

A total of 67 chronic gastritis patients (61.2% girls) with a mean age of 13.09 ± 3.5 years were evaluated. The mean FC levels were 153.4 μg/g in the chronic gastritis group, 589.7 μg/g in the IBD group and 43.8 μg/g in the healthy group. These levels were higher in chronic gastritis patients than in healthy individuals (P = 0.001) and higher in IBD patients than in the other two groups (P < 0.001). The FC level in the patients with chronic active gastritis (156.3 μg/g) was higher than in those with chronic inactive gastritis (150.95 μg/g) (P = 0.011). Among the patients with chronic active gastritis, the FC level was significantly higher in Helicobacter pylori-positive individuals than in negative individuals (P = 0.031).

We confirmed the association between increased FC and chronic gastritis. Elevated FC levels may be seen in patients with chronic active gastritis. In order to be able to use FC as a screening tool for chronic gastritis, further studies in a larger study group are needed.

We confirmed the association between increased FC and chronic gastritis. Elevated FC levels may be seen in patients with chronic active gastritis. GX15-070 ic50 In order to be able to use FC as a screening tool for chronic gastritis, further studies in a larger study group are needed.

Peripheral arterial disease (PAD) is characterized by progressive narrowing of the arterial lumen, resulting from atherosclerotic plaques. Treatment for PAD aims to control atherosclerosis and improve blood flow. Use of antiplatelet agents and anticoagulants has played important roles in helping to prevent occlusions and stenosis.

To evaluate the evidence from Cochrane systematic reviews regarding the accuracy, effectiveness and safety of use of anticoagulants and antiplatelets in lower-limb revascularization, in patients with peripheral arterial disease.

Systematic reviews found through searches in the Cochrane Library were included. Two authors evaluated whether the reviews found were in line with the inclusion criteria for this investigation. A qualitative synthesis of their findings was presented.

Three systematic Cochrane reviews were included. Patients who underwent prosthetic bypass surgery probably presented greater benefit from use of antiplatelets, and patients who underwent vein revascularization probably presented greater benefit from use of anticoagulants. Patients who received endovascular treatment benefited from both antiplatelet and anticoagulant treatment. However, the reliability of the results found was impaired because at the time when these reviews were published, there was no mandatory assessment using the GRADE criteria.

Despite the evidence found, it is necessary for these reviews to be updated in order to evaluate the degree of certainty of the results found.

Despite the evidence found, it is necessary for these reviews to be updated in order to evaluate the degree of certainty of the results found.Artificial intelligence (AI) is a general term used to describe the development of computer systems which can perform tasks that normally require human cognition. Machine learning (ML) is one subfield of AI, where computers learn rules from data, capturing its intrinsic statistical patterns and structures. Neural networks (NNs) have been increasingly employed for ML complex data. The application of multilayered NN is referred to as "deep learning", which has been recently investigated in dentistry. Convolutional neural networks (CNNs) are mainly used for processing large and complex imagery data, as they are able to extract image features like edges, corners, shapes, and macroscopic patterns using layers of filters. CNN algorithms allow to perform tasks like image classification, object detection and segmentation. The literature involving AI in dentistry has increased rapidly, so a methodological guidance for designing, conducting and reporting studies must be rigorously followed, including the improvement of datasets. The limited interaction between the dental field and the technical disciplines, however, remains a hurdle for applicable dental AI. Similarly, dental users must understand why and how AI applications work and decide to appraise their decisions critically. Generalizable and robust AI applications will eventually prove helpful for clinicians and patients alike.

to evaluate undergraduate nursing students' knowledge about intestinal ostomies before and after an educational intervention via an online platform.

before and after one-group type quasi-experimental research, carried out with 90 undergraduate nursing students from two higher education institutions in Piauí, from July to October 2014. For knowledge assessment, an instrument validated in Brazil was used. Nonparametric inferential statistics was used to compare the pre-test and post-test averages.

there was an increase in the average number of correct answers for undergraduate students after intervention in the online educational platform, from 23.67 (SD = 5.9) in the pre-test to 32.01 (SD = 2.72) in the post-test, and this difference was statistically significant (p = 0.000).

intervention via online educational platform is considered applicable for teaching undergraduate nursing students on intestinal ostomies.

intervention via online educational platform is considered applicable for teaching undergraduate nursing students on intestinal ostomies.

to understand the challenges of introducing gender debate in nursing training from undergraduate students' perspective.

a qualitative, exploratory-explanatory study. Data were collected through a semi-structured interview applied to 12 undergraduate nursing students at a public university in São Paulo. For data treatment and analysis, the Discourse of the Collective Subject was used in light of Boaventura de Sousa Santos' knowledge production paradigm theoretical framework.

nursing education remains centered on the traditional scientific model, neglecting gender and strengthening stereotypes aimed at the feminization of the profession.

nursing training has a challenge of implementing actions that deepen the gender theme. Therefore, some strategies are suggested, such as improving professor training and appropriating emancipatory pedagogical practices; reviewing pedagogical political projects; curriculum theorization and restructuring; problematizing gender issues for nursing leadership.

nursing training has a challenge of implementing actions that deepen the gender theme. Therefore, some strategies are suggested, such as improving professor training and appropriating emancipatory pedagogical practices; reviewing pedagogical political projects; curriculum theorization and restructuring; problematizing gender issues for nursing leadership.

to identify factors associated with homicides in women who had prior notification of violence in the state of Pernambuco, 2011 to 2016.

a transversal, quantitative and observational study, guided by the STROBE tool, with data of homicides of women obtained from the Mortality Information System; and of violence against women, from the Grievance Notification Information System. The logistic regression model was used to verify the factors associated with the homicides.

there were 32,308 cases of violence against women and 1,162 homicides. The chances of homicide were higher for women victims of physical violence (2.39 times more), aggression by object of court (2.32 times more), aggression by firearm (6 times more), and when there was a recurrence of violence (3.82 times more).

association of physical violence, agression by object of court, aggression by firearm, recurrence of violence with homicides of women in the state of Pernambuco was found.

association of physical violence, agression by object of court, aggression by firearm, recurrence of violence with homicides of women in the state of Pernambuco was found.

to identify the current state of knowledge on compassion fatigue in the work context of healthcare professionals; and how coping strategies are established in this scenario.

a scoping review with search applied to the databases MEDLINE, LILACS, CINAHL, Scopus. Temporal limit 2009 to 2019. The data was analyzed and synthesized in narrative form.

thirty articles were selected, synthesized into two categories a) Health work and compassion fatigue conceptual analysis, context, and manifestations; b) Coping strategies for compassion fatigue.

this study presented a descriptive and general panorama about compassion fatigue in healthcare professionals, identifying a greater consolidation of the concept between 2015 and 2018; and some coping strategies. The association between health and spirituality is highlighted as one of the strategies in this scenario, enabling new research to be conducted in view of the importance of the theme in life, health work.

this study presented a descriptive and general panorama about compassion fatigue in healthcare professionals, identifying a greater consolidation of the concept between 2015 and 2018; and some coping strategies.

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