Somervillesmith2908

It is believed that diets high in glycemic index (GI), glycemic load (GL), Insulin index (II), and Insulin load (IL) are associated with the increased risks of certain cancers through increasing serum glucose or insulin levels.

We conducted this systematic review of cohort studies to evaluate the possible relation between GI, GL, II, and IL with diabetes-related cancers, including colorectal, bladder, breast, endometrium, liver, pancreas, and prostate cancers. Two separate investigators conducted a literature search through PubMed/Medline, Scopus, and Web of Science databases up to February 2020, plus reference lists of relevant articles.

Fifty-three cohort studies with a total of 100098 cancer cases were included in this systematic review. Fifteen out of eighteen studies among breast cancer cases reported no significant association between GI/GL and cancer risk. These numbers were 4 out of 13 for colorectal cancer, 7 out of 9 for endometrial cancer, 2 out of 3 for liver cancer, 8 out of 10 for pancreatic cancer, and 3 out of 3 for prostate cancer. Only one cohort investigated this association in terms of bladder cancer and reported a significant association. Also, five studies reported this relation in terms of II/IL, and only one cohort among endometrial cancer patients observed a significant positive association between the risk of cancer and IL.

We concluded a weak association between dietary GI/GL and no association between II/IL with diabetes-related cancer risk. More cohort studies are required to be performed regarding II/IL and the risk of cancer.

We concluded a weak association between dietary GI/GL and no association between II/IL with diabetes-related cancer risk. More cohort studies are required to be performed regarding II/IL and the risk of cancer.

Obesity is a growing healthcare problem in Arabic-speaking countries although the effectiveness of the lifestyle modification program for weight management in this region is still lacking. Accordingly, this study aimed to assess long-term outcomes following an adapted lifestyle modification program based on cognitive behavioral therapy for obesity (CBT-OB) in Lebanon.

Forty-five adult participants with obesity were recruited consecutively at the Outpatient Clinic of the Department of Nutrition and Dietetics at Beirut Arab University (Lebanon). Patients were offered an individualized form of CBT-OB lasting 18 months comprising two phases (a weight loss phase of 6 months and a weight-maintenance phase of 12 months).

Twenty-five patients completed the treatment, with a mean weight loss of-11.58% after 6 months (-11.46% in the intention-to-treat analysis) and-8.84% after 18 months (-9.51% in the intention-to-treat analysis). Weight loss was associated with improvement in Health-Related Quality of Life (HRQoL) at six-month follow-up and in glycated hemoglobin (HbA1c) and body composition patterns at 18-month follow-up.

Our findings provide evidence supporting the use of CBT-OB for obesity as a standard in 'real-world' clinical setting in Lebanon. Future studies are needed on larger samples and other populations in Arab-speaking countries.

Our findings provide evidence supporting the use of CBT-OB for obesity as a standard in 'real-world' clinical setting in Lebanon. Future studies are needed on larger samples and other populations in Arab-speaking countries.

To describe a patient with Chagas' disease diagnosed with concomitant fibromyalgia and treated by an alternative approach and review the fibromyalgia-infections relationship.

The literature was reviewed for fibromyalgia association with infectious agents, using PubMed, spanning 2000-2020. The keywords were fibromyalgia, infections, bacteria, microbe, and parasite. A case report is described.

A 61-year-old female patient with a past medical history of Chagas' disease, presented with megaesophagus and dolichomegacolon for 30 years. Untreated anxiety accompanied her gastrointestinal manifestations. For the last ten years, she felt diffuse pain on both sides of the body, and in the upper and lower parts associated with sleep difficulties. On examination, she had 18 tender points, thus fulfilled the diagnostic criteria of fibromyalgia. Revumenib datasheet 25-OH vitamin D was 26ng/mL (>30ng/mL). Serology for Chagas' disease was positive by two techniques (ELISA and indirect immunofluorescence), and the routine laboratory was s not found.

The present case illustrates the first patient with Chagas-related dolichomegacolon who evolved with fibromyalgia and was successfully treated by psychotherapy, Pilates exercise, and vitamin D. It appears that myalgia and/or fibromyalgia are associated with numerous infectious agents, including parasites, but the association of fibromyalgia and T. cruzi, was not found.

Cystic Fibrosis (CF) may impact nutritional status. Handgrip strength (HGS) may be used for nutrition assessment. The objective of the study was to evaluate changes in HGS over time in children with CF compared to children without CF. A secondary purpose was to analyze the relationship of clinical characteristics of CF with HGS.

A prospective, longitudinal study was conducted. The non-CF group (n=76) was recruited from a school and the CF group (n=75) from an accredited CF center. Height, weight, mid-upper arm circumference, triceps skinfold, and HGS were measured at baseline and approximately three and six months in both groups. Data for pulmonary function, nutrition risk, enteral supplementation, CF transmembrane conductance regulator modulator, steroids, antibiotics, vitamin levels, CF related diabetes (CFRD), and recent hospitalization were collected for the CF group. A mixed model determined the difference in the change in HGS between the CF group and the non-CF group. For all analyses, p=<0.05 was significant.

The rate of change in HGS z-score in the CF-group (0.18±0.05) versus the non-CF group (0.06±0.06) was not significant (p=0.15). Initial mean dominant HGS z-score was significantly lower (p=0.02) in those with vitamin D deficiency (-1.35±0.09) versus those without (-1.02±0.11). HGS z-score significantly (p=0.02) decreased over time in children with CFRD (-0.19±0.22) versus children without CFRD (0.32±0.14), p=0.02.

Serial measurements of HGS may help detect changes in muscle function related to CFRD and vitamin D deficiency. Further investigation is warranted to elucidate HGS's role in nutrition assessment of children with CF.

Serial measurements of HGS may help detect changes in muscle function related to CFRD and vitamin D deficiency. Further investigation is warranted to elucidate HGS's role in nutrition assessment of children with CF.