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CUSTOMERS AND METHODS products and methods The audit was carried out into the number of 100 arbitrarily chosen nurses doing work in three various hospital wards Hospital Emergency Ward, Intensive Care device and Surgery Unit. Learn committed authors survey was developed as audits analysis tool. The study ended up being performed in May 2019. RESULTS outcomes the overall knowledge of nurses of sepsis is quite good. Almost all of the respondents responded correctly to questions about concept of sepsis and septic surprise, reasons for sepsis and relevant laboratory variables. Unfortunately, more in depth concerns, about diagnostic criteria or likelihood of total cure, caused more difficulties. Some responders are lacking up-to-date understanding of sepsis and septic surprise. CONCLUSION Conclusion More emphasis must be positioned on the availability of current informative data on sepsis and confirmation of this understanding of nurses employed in medical center are must certanly be taken fully to raise understanding and tension importance of current understanding to be able to supply the best quality and maximum effectiveness of patient care. Nurses doing work in the Hospital crisis Ward and Intensive Care Unit have more knowledge about the main topic of our research than the staff within the Surgical treatment Unit.OBJECTIVE desire to to review the organization between rs1899663-polymorphic variant of HOTAIR gene and clear cell renal cellular carcinoma (CCRCC) development in Ukrainian population. CLIENTS AND PRACTICES products and methods whole venous bloodstream from 101 Ukrainians with CCRCC (42 females and 59 men) and 100 control subjects (34 females and 66 men) were signed up for the study. DNA extraction had been performed making use of GeneJET Whole Blood Genomic DNA Purification Mini Kit (Thermo Fisher Scientific, American). Polymerase chain reaction-restriction fragment length polymorphism analysis (PCR-RFLP) was employed for HOTAIR rs1899663 genotyping. The Statistical Package for Social Science software (SPSS, version 17.0, Chicago, IL, American) was employed for all computations. RESULTS outcomes it had been found having less organization between HOTAIR rs1899663 solitary nucleotide polymorphism and CCRCC emergence along with cyst metastasis residential property in principal, recessive, over-dominant and additive crude models of inheritance, as well following the adjustment for age, sex, smoking and extortionate drinking (P > 0.05). CONCLUSION Conclusions No relationship had been discovered between HOTAIR rs1899663-polymorphic variant and CCRCC development in Ukrainian population. Additional studies with extended samples have to verify these outcomes.OBJECTIVE desire to The study of epidermis microbial landscape and immune-endocrine parameters also improvement of therapy performance in customers with different clinical length of psoriasis through the use of narrowband UVB phototherapy. CLIENTS AND TECHNIQUES products and methods We examined 89 customers with psoriasis (51 men and 38 ladies) aged 18-60. The comparison group consisted of 43 psoriasis patients similar by age, sex and clinical program with those through the main group (46 clients). Cytokine levels IL-4, IL-8, IL-10, TNFα, thyroid peroxidase (TPO) and thyroglobulin (Tg) autoantibodies and microbial flora of skin were determined in customers with psoriasis. RESULTS Results the research finds that mainstream therapy does not have adequate corrective impact on immune-endocrine disorders while the use of narrow-band light treatment has revealed so it has actually a focused corrective affect cytokine production and modulating effect on the degree of TPO and Tg autoantibodies together with condition of skin automicroflora of lesions in clients suffering from psoriasis. SUMMARY Conclusions Using UVB (311 nm) treatment in patients with psoriasis enables increasing effectiveness of therapy and limiting clinical indications by means of attaining remission and considerable improvement in customers' wellness without the unfavorable dynamic changes.INTRODUCTION Newborn jaundice is caused by enhanced amounts of bilirubin in the blood regarding the newborn through the very first times after birth. Generally speaking, neonatal jaundice does not need become addressed, but, if the blood bilirubin focus becomes way too high, it may cause neurological harm. As a result of prevalence of neonatal jaundice, it is essential to examine its threat facets and their particular value. This study during the nationwide raf signaling University Hospital of Iceland from 1997-2018, determines the danger aspects for serious neonatal jaundice and their particular significance. MATERIAL AND TECHNIQUES this is a retrospective instance control research performed at the National University Hospital of Iceland. It included all newborns identified as having serious jaundice (≥350 micromol/L) after a pregnancy of at least 37 days that have been addressed at the nationwide University Hospital of Iceland from 1997 until 2018. General information about the pregnancy, health of this youngster at beginning, as well as the diagnosis and remedy for jaundice ended up being collected.