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The pathological diagnosis was urothelial carcinoma pT1. Nine months later, recurrence showed up when you look at the bladder and then he underwent duplicated TURBT. The pathological diagnosis ended up being additionally pT1 in which he ended up being administered 8 courses of intravesical BCG treatment. Fourteen months following the very first procedure, computed tomography scans showed brand new lesions into the liver. Therefore, he had been known our medical center. Because biopsy from the hepatic lesion confirmed the analysis of metastatic urothelial carcinoma, he received 10 courses of gemcitabine plus cisplatin(GC)and radiofrequency ablation. Nonetheless, girl nodule and development associated with the main tumor had been uncovered on MRI 33 months following the preliminary TURBT. After 5 classes of pembrolizumab that limited the potential for hepatic metastases, he'd no proof other metastatic web sites and underwent laparoscopic right hepatectomy. There was clearly no viable carcinoma within the pathological specimens for the hepatic lesions. 6 months after hepatectomy, the in-patient has a top quality of life without having any recurrence.This is a primary report of gastrectomy after nivolumab immunotherapy. We describe an incident in an elderly woman with gastric disease diagnosed with cT4bN3M1(LYM), cStage ⅣB disease. Although she ended up being administered 2 classes of SOX chemotherapy since the major treatment, she could maybe not continue the treatment to because of bone tissue marrowsuppression. The second-line therapy had been weekly PTX treatment, but she practiced Grade 3 neutropenia and thrombocytopenia in the first program and could perhaps not carry on treatment. Nivolumab once the next treatment had been efficient but ended up being discontinued for suspected druginduced pneumonia. Throughout that time, tumefaction hemorrhage took place and we performed complete gastrectomy. Postoperatively, nivolumab chemotherapy ended up being started again. There were no negative events therefore the patient has had a continued limited response for 30 classes. Gastrectomy ended up being required in this case, allowing observation associated with pathological findings of the effective case.A 74-year-old man underwent distal gastrectomy for gastric cancer(CY1, fStage Ⅳ). About 18 months after surgery, stomach CT scans revealed multiple lymph node metastases across the portal vein. Systemic chemotherapy ended up being administered comprising a capecitabine/oxaliplatin(CAPOX)regimen. After 4 classes of chemotherapy, a detrimental result of level 2 diarrhoea and peripheral neuropathy occurred, although regression of this lymph node metastasis had been confirmed. Ramucirumab ended up being administered since the second-line program, but CT imaging unveiled lymph node progression after a few classes. Although irinotecan(CPT-11)was selected since the third-line chemotherapy, the lymph node development stayed uncontrolled. Nivolumab ended up being chosen while the fourth-line chemotherapy. After 23 courses, nivolumab immunotherapy induced a partial a reaction to the lymph node metastasis. Nivolumab immunotherapy is still administered so far, 5 years after the operation. We experienced an instance of lymph node metastasis from gastric cancer effectively addressed with nivolumab chemotherapy.A 55-year-old man ended up being admitted to our hospital for jaundice. Magnetized resonance cholangiopancreatography revealed a mass in the pancreatic head along with biliary obstruction. We strongly suspected unpleasant ductal carcinoma associated with pancreas. We performed pancreaticoduodenectomy with partial resection for the portal vein. The histopathological analysis had been small cellular carcinoma regarding the pancreas. We detected metastasis associated with right hilar lymph node in PET-CT scan done 2 months after the surgery and started chemotherapy with cisplatin(CDDP)plus irinotecan(CPT-11). However, we observed recurrent metastasis of this right hilar lymph node 12 months after the surgery. We began second-line chemotherapy with amrubicin( AMR)and radiotherapy. Sadly, the individual died from multiple metastases of this left adrenal gland and mind 26 months following the surgery. The prognosis of small cellular carcinoma of this pancreas is very bad. Multimodal therapy such chemotherapy, radiotherapy, and curative procedure are expected for long-term survival.A 43-year-old girl who underwent medical resection of invasive ductal carcinoma within the remaining breast in the chronilogical age of 37 yrs old presented at our hospital for assessment of pancreatic tumor. The first tumor had been estrogen receptor(ER)progesterone receptor(PgR)and HER2 good. During those times, she underwent radical mastectomy with no obvious nodal disease. Postoperatively, the individual was positioned on adjuvant tamoxifen treatment for a long time. Six many years following the initial diagnosis of cancer of the breast, she was known the medical center for routine check-up while asymptomatic. Follow-up examination showed a solitary hypodense size around 0.9 cm in dimensions in the pancreas human body on powerful CT scan. The client underwent a regular distal pancreatectomy with standard local lymphadenectomy. Histopathological assessment and immunohistochemical functions revealed that the cyst was p505-15 inhibitor compatible with metastatic pancreatic adenocarcinoma from breast cancer.A 69-year-old man underwent a Miles operation with D3 lymph node dissection for rectal cancer tumors. The pathological analysis was adenocarcinoma(Rb, A, ly2, v3, N2M0P0H0, Stage Ⅲb). Adjuvant chemotherapy ended up being added for half a year following the rectal resection. Metastasis into the left lung was recognized one year and 10 months after rectal resection for which large segmental resection ended up being done.