Simonsenmccray8999

These results may have potential importance for future applications of NRNPs pH in preclinical and perhaps clinical studies.Given the excessive foul language identified in audio and video files and the detrimental consequences to an individual's character and behaviour, content censorship is crucial to filter profanities from young viewers with higher exposure to uncensored content. Although manual detection and censorship were implemented, the methods proved tedious. Inevitably, misidentifications involving foul language owing to human weariness and the low performance in human visual systems concerning long screening time occurred. As such, this paper proposed an intelligent system for foul language censorship through a mechanized and strong detection method using advanced deep Convolutional Neural Networks (CNNs) and Recurrent Neural Networks (RNNs) through Long Short-Term Memory (LSTM) cells. Data on foul language were collected, annotated, augmented, and analysed for the development and evaluation of both CNN and RNN configurations. Hence, the results indicated the feasibility of the suggested systems by reporting a high volume of curse word identifications with only 2.53% to 5.92% of False Negative Rate (FNR). The proposed system outperformed state-of-the-art pre-trained neural networks on the novel foul language dataset and proved to reduce the computational cost with minimal trainable parameters.Posidonia oceanica (L.) Delile is traditionally used for its beneficial properties. Recently, promising antioxidant and anti-inflammatory biological properties emerged through studying the in vitro activity of the ethanolic leaves extract (POE). The present study aims to investigate the anti-inflammatory and analgesic role of POE in mice. Inflammatory pain was modeled in CD-1 mice by the intraplantar injection of carrageenan, interleukin IL-1β and formalin. Pain threshold was measured by von Frey and paw pressure tests. Nociceptive pain was studied by the hot-plate test. POE (10-100 mg kg-1) was administered per os. The paw soft tissue of carrageenan-treated animals was analyzed to measure anti-inflammatory and antioxidant effects. POE exerted a dose-dependent, acute anti-inflammatory effect able to counteract carrageenan-induced pain and paw oedema. Similar anti-hyperalgesic and anti-allodynic results were obtained when inflammation was induced by IL-1β. In the formalin test, the pre-treatment with POE significantly reduced the nocifensive behavior. Moreover, POE was able to evoke an analgesic effect in naïve animals. Ex vivo, POE reduced the myeloperoxidase activity as well as TNF-α and IL-1β levels; further antioxidant properties were highlighted as a reduction in NO concentration. POE is the candidate for a new valid strategy against inflammation and pain.The article presents an innovative method of reducing welding distortions of thin-walled structures by introducing structural and technological changes. The accuracy of the method was demonstrated on the example of welding the stub pipes to the outer surface of a thin-walled tank with large dimensions, made of steel 1.4301 with a wall thickness of 1.5 × 10-3 (m). During traditional Gas Tungsten Arc Welding (GTAW), distortions of the base are formed, the flatness deviation of which was 11.9 × 10-3 (m) and exceeded the permissible standards. As a result of structural and technological changes, not only does the joint stiffness increase, but also a favorable stress state is introduced in the flange, which reduces the local welding stresses. Numerical models were developed using the finite element method (FEM), which were used to analyze the residual stresses and strains pre-welding, in extruded flanges, in transient, and post-welding. The results of the calculations for various flanges heights show that there is a limit height h = 9.2 × 10-3 (m), above which flange cracks during extrusion. A function for calculating the flange height was developed due to the required stress state. The results of numerical calculations were verified experimentally on a designed and built test stand for extrusion the flange. The results of experimental research confirmed the results of numerical simulations. For further tests, bases with a flange h = 6 × 10-3 (m) were used, to which a stub pipe was welded using the GTAW method. After the welding process, the distortion of the base was measured with the ATOS III scanner (GOM a Zeiss company, Oberkochen, Germany). It has been shown that the developed methodology is correct, and the introduced structural and technological changes result in a favorable reduction of welding stresses and a reduction in the flatness deviation of the base in the welded joint to 0.39 × 10-3 (m), which meets the requirements of the standards.The structure of the Co2MnAl-type Heusler alloy in the form of a melt-spun ribbon was studied by electron microscopy, electron back-scattered diffraction (EBSD), and X-ray diffraction. The melt-spun ribbon consists of a homogeneous single-phase disordered Heusler alloy at the wheel side of the ribbon and an inhomogeneous single-phase alloy, formed by cellular or dendritic growth, at the free surface of the ribbon. Cellular growth causes the formation of an inhomogeneous distribution of the elemental constituents, with a higher Co and Al concentration in the centre of the cells or dendritic arms and a higher concentration of Mn at the cell boundaries. The EBSD analysis shows that the columnar crystals grow in the crystal direction and are declined by about 10° against the direction of the spinning.Maize is one of the most important cereal crop species due to its uses for human and cattle nourishment, as well as its industrial use as a raw material. The yield and grain quality of maize depend on plant establishment, which starts with germination. Germination is dependent on embryo vigor and the stored reserves in the scutellum and endosperm. During germination, the scutellum epidermis changes and secretes enzymes and hormones into the endosperm. As a result, the hydrolysis products of the reserves and the different soluble nutrients are translocated to the scutellum through epithelial cells. Then, the reserves are directed to the embryo axis to sustain its growth. Therefore, the microenvironment surrounding the scutellum modulates its function. Zinc (Zn) is a micronutrient stored in the maize scutellum and endosperm; during imbibition, Zn from the endosperm is solubilized and mobilized towards the scutellum. selleck During this process, Zn first becomes concentrated and interacts with cell wall charges, after which excess Zn is internalized in the vacuole.