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05 for all cases), and had no significant differencesinthese parameters betweenginger and control group were found.

It can be concluded that ginger extract has protective effects against toxicity induced by ethanol in the eye of male rat.

It can be concluded that ginger extract has protective effects against toxicity induced by ethanol in the eye of male rat.

Numerous studies demonstrated the effect of grape on memory improvement. According to Iranian traditional medicine, "mavizˮ as a specific type of dried grapes can effectively improve memory. However, there is no reported clinical trial on the effect of "mavizˮ on memory improvement in humans. Hence, this study was conducted to investigate "mavizˮ effect on memory in university students.

This randomized open-label clinical trial was conducted on a total number of 53 students of Shahed University, Tehran, Iran, from November 2017 to February 2018. The participants were randomly allocated into an intervention group (receiving "mavizˮ, 25 g in the morning for 4 weeks) or a control group (who did not take "mavizˮ). The Digit Span Task and the N-Back Task were used for the measurement of working memory at the pre- and post-intervention stages.

According to the results, no significant differences were found between the two groups regarding age, gender, marital status, and initial working memory test scores. "mavizˮ consumption produced a highly significant improvement in total working memory score in the Digit Span Task (5.18 vs. 2.35, p<0.001) and Acoustic Memory Span (1.29 vs. 0.62, p=0.021). Moreover, "mavizˮ consumption significantly increased the percentage of true responses in the N-Back Task and reduced the mean reaction time in the first level of the task.

"mavizˮ consumption was improved working memory in young healthy adults.

"mavizˮ consumption was improved working memory in young healthy adults.

Methamphetamine (METH) increases dopamine, norepinephrine and serotonin concentrations in the synaptic cleft, and induces hyperactivity. The current management of acute METH poisoning relies on supportive care and no specific antidote is available for treatment. The main objective of this review was to present the evidence for effectiveness of the herbal medicine in alleviating the adverse effects of METH abuse.

Literature search was performed using the following electronic databases MEDLINE, Scopus, PubMed and EMBASE.

Plant-derived natural products ginseng and sauchinone reduced METH-induced hyperactivity, conditioned place preference and neurological disorder.

decreased METH-induced hepatotoxicity, raised METH lethal dose, and restored the METH-impaired cognitive function. Repeated administration of baicalein resulted in attenuation of acute binge METH-induced amnesia via dopamine receptors. Activation of extracellular-regulated kinase in the hypothalamus by levo-tetrahydropalmatine facilitated the extinction of METH-induced conditioned place preference and reduced the hyperactivity. Other herbal medicine from various parts of the world were also discussed including hispidulin, silymarin, limonene, resveratrol, chlorogenic acid and barakol.

Based on the current study, some natural products such as ginseng and levo-tetrahydropalmatine are promising candidates to treat METH abuse and poisoning. However, clinical trials are needed to confirm these finding.

Based on the current study, some natural products such as ginseng and levo-tetrahydropalmatine are promising candidates to treat METH abuse and poisoning. However, clinical trials are needed to confirm these finding.

This study aims to evaluate the effects of onion (

L.) against hyperglycaemia and dyslipidemia and determine possible changes in these effects due to different heat treatments applied to onion.

32 male Wistar-albino rats were divided into 4 groups as follows the groups C and DC were fed with standard rat diet; the DLO group was fed with rat diet including 5% onion powder dried at -76°C in a lyophilizator, and the DFO group was fed with rat diet including 5% onion powder dried at 80°C in a furnace. Diabetes was induced in DC, DLO and DFO groups by injection of streptozotocin (45 mg/kg).

A decreasing tendency was observed in fasting blood glucose (FBG) values of DLO group during the experiment period and it was found that the 6th and 8th weeks values were significantly lower than the 1st and 2nd weeks values (p<0.05). Ubiquitin inhibitor On the other hand, no statistical difference was observed in the FBG values measured at different weeks in the DFO group. Significant differences were also observed among the groups in terms of plasma lipid values. DLO group was determined to have lower levels of triglyceride (p<0.001), LDL cholesterol and total cholesterol and higher levels of HDL cholesterol (p<0.05 for all cases) compared to the DC group whereas no significant difference in these values was found between the DFO and DC groups.

Lyophilized onion powder may be protective against hyperglycaemia and dyslipidemia arising from diabetes. However, the heat treatments applied to onion affect this protective role negatively.

Lyophilized onion powder may be protective against hyperglycaemia and dyslipidemia arising from diabetes. However, the heat treatments applied to onion affect this protective role negatively.

Individuals with benign kidney disorders undergoing nephrectomy have three possibilities Autotransplantation, with a certain risk of complications, but without a clear benefit; discarding the kidney; or living kidney donation.

To investigate whether patients with benign kidney disorders and a medical indication for nephrectomy are suitable as unspecified live kidney donors.

We searched all clinical data from 1994-2019 for unspecified donors and their transplant recipients (

= 160). Nine of these 160 donors had pre-existing kidney disorders necessitating nephrectomy and had decided to donate their kidney anonymously after discussing the possibility of kidney donation. We studied the clinical course of these nine donating patients and their transplant recipients.

Seven of nine donating patients indicated unbearable loin pain as the main complaint, one donating patient refused ureterocutaneostomy and one had two aneurysms of the renal artery. Postoperatively, seven donating patients described absence of pain and one a significant reduction after the nephrectomy.