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Nonetheless, as for SARS-CoV and MERS CoV, the Spillover effect linked to animal-human promiscuity, human activities including deforestation, illegal bush-trafficking and bushmeat, cannot be excluded. Recently, however, evidence of inter-human only transmission of SARS-CoV-2 has been accumulated and thus, the outbreak seems to be spreading by human-to-human transmission throughout a large part of the world. Herein we will provide with an update on the main features of COVID-19 and suggest possible solutions how to halt the expansion of this novel pandemic. Copyright (c) 2020 Carlo Contini, Mariachiara Di Nuzzo, Nicole Barp, Aurora Bonazza, Roberto De Giorgio, Mauro Tognon, Salvatore Rubino.Currently, the outbreak of COVID-19 is rapidly spreading especially in Wuhan city, and threatens 14 million people in central China. In the present study we applied the Moran index, a strong statistical tool, to the spatial panel to show that COVID-19 infection is spatially dependent and mainly spread from Hubei Province in Central China to neighbouring areas. Logistic model was employed according to the trend of available data, which shows the difference between Hubei Province and outside of it. We also calculated the reproduction number R0 for the range of [2.23, 2.51] via SEIR model. The measures to reduce or prevent the virus spread should be implemented, and we expect our data-driven modeling analysis providing some insights to identify and prepare for the future virus control. Copyright (c) 2020 Rui Huang, Miao Liu, Yongmei Ding.The laboratory plays a significant role in public health surveillance, outbreak investigation and infection prevention and control strategies. Microbiology laboratories are moving towards incorporating molecular biology techniques for the surveillance and identification of pathogens causing infectious diseases as well as the genotypic characterisation of these organisms. These methods are accurate, rapid, reliable, and provide a wealth of information that are not available using conventional phenotypic methods. However, establishing such a laboratory can be challenging in developing countries due to poor infrastructure, the lack of funding and the required expertise. This manuscript discusses the essential issues that need to be addressed when establishing a molecular microbiology laboratory and the usefulness of molecular techniques in public health surveillance and outbreaks in developing countries. Molecular data on South African findings obtained from surveillance and outbreak studies are also presented in this manuscript. Copyright (c) 2020 Ashika Singh-Moodley, Husna Ismail, Olga Perovic.In recent years, quasi-one-dimensional semiconductor nanowires have attracted numerous research interests in the field of optoelectronic devices. Indium arsenide (InAs) nanowire, an III-V compound semiconductor structure with a narrow bandgap, shows high electron mobility and high absorption from the visible to the mid-wave infrared (MWIR), holding promise for roomtemperature high-performance infrared photodetectors. Therefore, the material growth, device preparation, and performance characteristics have attracted increasing attention, enabling high sensitivity InAs nanowire photodetector from the visible to the MWIR at room temperature. Tovorafenib This review starts by discussing the growth process of the low-dimensional structure and elementary properties of the material, such as the crystalline phase, mobility, morphology, surface states, and metal contacts. Then, three solutions, including the visible-light assisted infrared photodetection technology, the vertical nanowire array technology, and band engineering by the growth of InAsSb nanowires with increasing Sb components, are elaborated to obtain longer cut-off wavelength MWIR photodetectors based on single InAs nanowire and its heterojunction structure. Finally, the potentials and challenges of the state-of-the-art optoelectronic technologies for InAs nanowire MWIR photodetectors are summarized and compared, and preliminary suggestions for the technical development route and prospects are presented. This review mainly delineates the research progress of material growth, device fabrication and performance characterization of InAs nanowire MWIR photodetectors, providing a reference for the development of the next-generation high-performance photodetectors over a wide spectrum range. © 2020 IOP Publishing Ltd.The ion recombination is examined in parallel-plate ionization chambers in scanning proton beams at the Danish Centre for Particle Therapy and the Skandion Clinic. The recombination correction factorksis investigated for clinically relevant energies between 70 MeV and 224 MeV for dose rates below 400 Gy/min in air. The Boutillon formalism is used to separate the initial and general recombination. The general recombination is compared to predictions from the numerical recombination code IonTracks and the initial recombination to the Jaffé theory.ksis furthermore calculated with the two-voltage method (TVM) and extrapolation approaches, in particular the recently proposed three-voltage (3VL) method.. The TVM is in agreement with the Boutillon method and IonTracks for dose rates above 100 Gy/min. However, the TVM calculatedksis closer related to the Jaffé theory for initial recombination for lower dose rate, indicating a limited application in scanning light ion beams. The 3VL is in turn found to generally be in agreement with Boutillon's method. The recombination is mapped as a function of the dose rate and proton energy at the two centres using the Boutillon formalism the initial recombination parameter was found to beA=(0.10±0.01) V at DCPT andA=(0.22±0.13) V at Skandion, which is in better agreement with the Jaffé theory for initial recombination than previously reported values. The general recombination parameter was estimated tom2= (4.7±0.1)×103V2nA-1cm-1andm2= (7.2±0.1)×103V2nA-1cm-1. Furthermore, the numerical algorithm IonTracks is demonstrated to correctly predict the initial recombination at low dose rates and general recombination at high dose rates. © 2020 Institute of Physics and Engineering in Medicine.

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