Sellersmaclean1946

A 54-year-old woman was brought to our emergency department with an inferomedial open hip dislocation without fracture secondary to a railway trauma. We performed hip reduction, wound debridement, and stabilization with external fixation. After 7 months, hip arthroplasty was performed for severe hip instability and avascular necrosis of the femoral head.

Open hip dislocation is an uncommon injury that is caused by high-energy trauma. It may be associated with serious management problems and complications, including infection and avascular necrosis of the femoral head.

Open hip dislocation is an uncommon injury that is caused by high-energy trauma. It may be associated with serious management problems and complications, including infection and avascular necrosis of the femoral head.

Distal radius fractures are among the most common orthopaedic injuries. The volar locking plate is now the most utilized internal fixation method for these fractures. There are few reports of mechanical failure of volar locking plates within the literature. In this case report, we describe successful closed reduction of traumatic volar locking plate plastic deformation with associated fracture. In addition, we discuss existing literature regarding plastic deformation of distal radius plates.

Traumatic, plastic deformation of distal radius volar locking plates with associated fracture may be managed nonoperatively with closed reduction.

Traumatic, plastic deformation of distal radius volar locking plates with associated fracture may be managed nonoperatively with closed reduction.

A 50-year-old woman with a history of bilateral knee replacements developed acute-onset bilateral painful knee effusions and inability to weight-bear. She was systemically well, but 2 days before the onset of her symptoms, she received an influenza vaccination. Synovial fluid analysis revealed white cell count (WCC) 190,000 × 109, 85% polymorphomuclear lymphocytes (PMN) on the left knee and WCC 252,200 × 109, 89% PMN on the right knee. Debridement and implant retention and polyethylene exchange was performed. Extended bacterial culture was negative as was 16s RNA polymerase chain reaction for remnants of bacterial DNA. No crystals were seen on any specimen. Both knees are stable and pain free at 12-month follow-up.

Reactive arthritis secondary to influenza vaccination is a rare condition that can mimic prosthetic joint infection.

Reactive arthritis secondary to influenza vaccination is a rare condition that can mimic prosthetic joint infection.This study investigates the role of CPEB3 in esophageal cancer (EC) progression. The prognosis of EC patients was shown by survival analysis. CPEB3-targeting microRNAs were predicted by bioinformatics tools and further validated by dual-luciferase assay and RNA immunoprecipitation. CPEB3 expression in EC cell lines and EC tissues was analyzed by quantitative reverse transcription PCR. The viabilities of KYSE150 and EC9706 cells were measured by MTT and Cell Counting Kit-8 assays. The migration, invasion and tube formation of KYSE150 and EC9706 cells were examined by wound healing, Transwell and tube formation assay, respectively. E-cadherin, N-cadherin, fibronectin, vimentin and vascular endothelial growth factor (VEGF), epidermal growth factor receptor (EGFR) [and phosphorylation (p)] and STAT3 levels (and phosphorylation) in KYSE150 and EC9706 cells were determined by western blot analysis or quantitative reverse transcription PCR. In addition, a xenograft tumor model was established through subcutaneously implanting KYSE150 and EC9706 cells transfected with Lv-CPEB3 or Lv-control viruses. CPEB3 expression was downregulated in EC cells and tissues, and its overexpression inhibited viability, migration, invasion and the expressions of N-cadherin, fibronectin, vimentin and VEGF, EGFR, p-EGFR and p-STAT3 levels in KYSE150 cells, but promoted E-cadherin expression. Small interfering RNA (siRNA)-CPEB3 inversely affected these phenotypes and gene expressions in EC9706 cells. EUK 134 purchase miR-106b-5p targeted CPEB3 and negatively regulated CPEB3 expression. miR-106b-5p mimics reversed the effect of CPEB3 overexpression on KYSE150 cells, and miR-106b-5p inhibitor reversed the effect of siRNA-CPEB3 on EC9706 cells. In mice, tumor volumes, weights and Ki-67 expression were lower in mice treated with Lv-CPEB3 than that with Lv-control. CPEB3 overexpressed by miR-106b-5p inhibition suppressed EC progression involved in EGFR and STAT3 signaling.

A 29-year-old man with an open tibia fracture and a 15-cm bone defect was treated with irrigation, debridement, intramedullary nailing, soft-tissue flap, and bone transport with a frame over the nail. He developed osteomyelitis of his bone transport segment close to docking, which required bone resection and an induced membrane technique to salvage his transport segment and achieve union.

This report illustrates the combined use of bone transport and induced membrane technique to achieve union in a 15-cm tibial defect. It demonstrates the use of the Masquelet technique to salvage an infected bone transport segment.

This report illustrates the combined use of bone transport and induced membrane technique to achieve union in a 15-cm tibial defect. It demonstrates the use of the Masquelet technique to salvage an infected bone transport segment.

Two-bone forearm reconstruction after tumor resection in pediatric patients is challenging. We present a case of forearm reconstruction in a girl who underwent resection of a high-grade surface osteosarcoma involving the ulna and radius. A free vascularized fibular graft was osteotomized to 2 struts to reconstruct the two-bone defect. The patient recovered well but returned for excision of ossification of the periosteum hinge occurring 6 months postoperatively.

Neither recurrence nor metastasis was observed during the 5-year follow-up. Although there was a 50° loss of pronation and the left-vs.-right forearm discrepancy was 4 cm, she was able to resume her daily activities.

Neither recurrence nor metastasis was observed during the 5-year follow-up. Although there was a 50° loss of pronation and the left-vs.-right forearm discrepancy was 4 cm, she was able to resume her daily activities.

This is a case of a 14-year-old female athlete with cuboid syndrome who underwent calcaneocuboid ligament complex reconstruction using a palmaris tendon allograft that was passed through 2 parallel extra-articular dorsoplantar bone tunnels through the calcaneus and cuboid. She returned to high-impact activities within 6 months. Two-and-a-half years postoperative, she continues sports with only minor stints of pain relieved with rest.

Consensus regarding surgical treatment of cuboid syndrome has not been reached. This case report highlights a successful surgical technique for calcaneocuboid instability with potential for return to sports. We found 2 similar case reports in the literature.

Consensus regarding surgical treatment of cuboid syndrome has not been reached. This case report highlights a successful surgical technique for calcaneocuboid instability with potential for return to sports. We found 2 similar case reports in the literature.

Since 2010, the number of programs and available positions for integrated plastic surgery residency has increased, yet the match rate remains one of the lowest of all specialties, and the applicant pool remains one of the most competitive. We sought to investigate whether this increased interest in integrated programs has translated to increased online search volume regarding plastic surgery residency.

Our study uses Google Trends, a powerful online tool that analyzes changes in Google search volume over time and across various regions, to study temporal and geographic trends in search interest for terms related to plastic surgery residency from July 2009 to 2020 in the United States.

Terms related to plastic surgery research, step 1 and 2 scores, and residency interviews had the most search results, whereas terms related to away rotations and Alpha Omega Alpha had the least. "Independent plastic surgery track" had more total search results on Google than "integrated plastic surgery residency," and "plathat there are clearly other factors that influence medical students' interest in plastic surgery residency besides Internet research.

This Google Trends analysis showed discordance between the upward trend in integrated plastic surgery residency positions offered through the National Residency Match Program and relatively unchanging search interest in factors related to the plastic surgery residency application. However, interest in a plastic surgeon's salary has increased over time, but this is not specific to plastic surgery. Although online search tools can be of important predictive value, this study demonstrates that there are clearly other factors that influence medical students' interest in plastic surgery residency besides Internet research.

Fresh fat grafts are commonly used in both esthetic and reconstructive surgeries, but the graft resorption rate varies. Cryopreservation of unused fat for later touch-up is one option to resolve this variation. In our previous studies, we found that fat cryopreservation may be a practical strategy for storing fat tissue. To explore the cryopreservation method, we evaluated the role of vascular endothelial growth factor (VEGF) in human frozen fat grafts.

The concentration of VEGF in human frozen fat grafts subjected to different preservation times was determined using Western blotting and enzyme-linked immunosorbent assay. The angiogenic effect of frozen fat grafts was evaluated using a chorioallantoic membrane assay. Furthermore, the impact of adding human adipose-derived stem cells (hADSCs) or different concentrations of avastin (bevacizumab) to frozen fat grafts on angiogenesis was assessed. The viability of frozen fat grafts with or without hADSCs was evaluated using a nude mouse implantation study. Exther enhance angiogenesis, VEGF expression, and fat cell viability.

Human fat grafts can maintain VEGF expression under frozen conditions for at least 12 months. The addition of hADSCs to the frozen fat graft could further enhance angiogenesis, VEGF expression, and fat cell viability.

Vascularized composite allotransplantation (VCA) allows functional and esthetic reconstruction for patients with complex anatomical defects. However, acute and chronic graft rejections are significant obstacles to VCA. Ultraviolet light is an oncogenic environmental hazard. However, ultraviolet B (UVB) has an immunomodulation effect. Therefore, this study aims to elucidate the impact of UVB irradiation on the VCA rat model.

The rat vascularized bone marrow allotransplantation model was used. A vascularized bone marrow from a Brown Norway rat (RT1Ac) was transplanted into a Lewis rat (RT1Ab). The allograft and surrounding abdominal skin were exposed to narrow-band ultraviolet B (NB-UVB) (311 nm) radiation with an energy of 1350 mJ/cm2 3 times a week until the end of the study period. There were 5 study groups syngeneic transplantation (group 1), allogeneic transplantation (group 2), allogenic transplantation-NB-UVB (group 3), allogenic transplantation-antilymphocyte serum (ALS)-tacrolimus (group 4), and allogenic transplantation-antilymphocyte serum-tacrolimus-NB-UVB (group 5).