Schaeferwise8608

Bettering evidence-based practice by way of preregistration involving used research: Boundaries and proposals.

Thinking processes Circle: Higher Buy vs. More Discrimination.

4% of patients classified as having mild disease were inadequately controlled, compared to 94.5% of patients classified with severe disease. CRCD2 Relative to patients with controlled disease, patients with inadequately controlled disease were more likely to be unemployed, reported more frequent flares, and had a greater burden of symptoms and worse quality of life measures including itch, stress, anxiety, depression, and sleep disturbance (all p < 0.0001).

Despite the introduction of new therapies, the burden and impact of AD and lack of symptom control, although reduced compared with previous studies, still remains high.

Despite the introduction of new therapies, the burden and impact of AD and lack of symptom control, although reduced compared with previous studies, still remains high.

To test the association between racial discrimination and cardiovascular-related conditions and whether PTSD mediates this relationship in a nationally representative sample of non-Hispanic Blacks.

We used data from the 2013 National Epidemiologic Survey on Alcohol and Related Conditions to conduct logistic regression analyses to examine the association between racial discrimination, PTSD, and cardiovascular-related conditions. We also performed mediation analyses to assess whether the association between racial discrimination and cardiovascular conditions was partly explained by PTSD.

Racial discrimination was positively associated with both PTSD and cardiovascular-related conditions. link2 Additionally, PTSD was positively associated with cardiovascular conditions. Results from the fully adjusted mediation models suggest that PTSD significantly mediated the association between racial discrimination and cardiovascular conditions.

Our results demonstrate an association between racial discrimination and cardiovascular-related conditions that is significantly mediated by PTSD. CRCD2 To improve cardiovascular functioning among non-Hispanic Blacks, health care professionals in conjunction with Black communities must adopt culturally competent screening for and treatment for PTSD. To address racial differences in cardiovascular conditions, public health efforts must address institutional policies that negatively alter health opportunities among the Black population.

Our results demonstrate an association between racial discrimination and cardiovascular-related conditions that is significantly mediated by PTSD. To improve cardiovascular functioning among non-Hispanic Blacks, health care professionals in conjunction with Black communities must adopt culturally competent screening for and treatment for PTSD. To address racial differences in cardiovascular conditions, public health efforts must address institutional policies that negatively alter health opportunities among the Black population.Stapler-less laparoscopic sleeve gastrectomy (LSG) is emerging as a new potential affordable cost-effective alternative procedure. However, no pre-clinical data are currently available on human tissue. We aimed to evaluate whether traditionally suturing without the use of surgical stapling may produce a comparable bursting pressure on human gastric tissue. A prospective cohort of consecutive patients undergoing LSG was divided in two groups to compare a barbed extra-mucosal running suture (stapler-less) versus a standard stapler line. A burst pressure test was applied to the gastric specimen employing high-resolution manometric catheter. Type, location and features of the leak were described. We enrolled a total of 40 obese patients, 20 patients for each group. Median burst pressures of the stapler-less group resulted statistically significant increased (p  less then  0.0001) than the one in standard stapler group. In all cases, leak occurred along the surgical closure site independently from the used technique (group 1 vs 2; p = N.S.), more often at the proximal stomach (p  less then  0.05). In human ex vivo model, traditional surgical suture (i.e. running hand-sewn) produced an effective temporary closure, with superior resistance to increasing volume and pressure. How this may impact on clinical LSG outcomes needs further evaluations and was not the object of this study.The development of an effective approach to improve low-temperature nitrification of domestic wastewater remains an important issue that needs to be urgently addressed. This study was intended to verify the feasibility of using iron scraps as an effective immobilization material to enhance nitrification activity in domestic wastewater-treatment systems at low temperatures. Iron scraps were tried and compared with one common immobilization material (PVA-SA embedded balls) in terms of low-temperature nitrification performances, anti-shock capacity, dynamics of microbial community, and economic costs. The results showed that compared with control, the average nitrification efficiency of iron scraps and PVA-SA embedded balls increased separately by 15.7% and 27.6% at low temperatures. CRCD2 Among these groups, the iron scrap-based group demonstrated the best anti-shock capacity and the smallest fluctuation (lower than 10%) with the shortening of HRT (hydraulic retention time) or the increase of inlet ammonium level. Nitrosomonas was found to be the dominant bacterial genera for these two immobilization materials. link2 The increased costs of iron scraps and PVA-SA embedded balls were about ¥0.03 and ¥0.78 per ton of treated domestic wastewater. Taken together, iron scraps have some significant advantages including low costs, easy availability, and good anti-shock capacity, which make them a promising candidate for enhanced nitrification of domestic wastewater at low temperatures.Metal-free carbonaceous composite membranes have been proven to effectively drive novel in situ catalytic oxidation for the degradation of organic pollutants via persulfates activation. link2 In this study, nitrogen-doped graphene (NG) was employed as a modifier to enhance the catalytic activity of the carbon mats by assembly with reduced graphene oxide (rGO) and carbon nanotubes (CNTs) on the top of a nylon supporter. The morphology and performance of the NG/rGO/CNTs composite membrane were compared to those obtained without the addition of NG (rGO/CNTs). Owing to the larger nanochannels for water delivery and stronger hydrophobicity on the surface, the NG/rGO/CNTs composite membrane shows a superior low-pressure filtration performance in favor of energy-saving operation. For the in situ catalytic oxidation of the NG/rGO/CNTs composite membrane through the activation of peroxydisufate (PDS), the average removal rate of sulfamethoxazole (SMX), one of frequently detected sulfonamide antibiotics in water, can reach 21.7 mg·m-2·h-1 under continuous filtration mode, which was 17% more rapid than that of the rGO/CNTs, resulting in significant detoxifying of the oxidation intermediates. Owing to the addition of NG into the carbon mats, the reactive nitrogen-doped sites identified by X-Ray photoelectron spectroscopy (XPS), such as pyridinic and graphitic N, played important roles in PDS activation, while both the radical and non-radical pathways were involved in in situ catalytic oxidation. link3 According to the experimental evidence of the effects that solution environment has on the SMX removal and transmembrane pressure, the NG/rGO/CNTs composite membrane shows a relatively high resistance to changes in the solution pH, chloride ion inhibition, and background organics fouling. These results suggest a new approach to the application of activated persulfate oxidation in water treatment, such that improvements to the reaction stability warrant further investigation.To utilize carbon source and decompose the petroleum hydrocarbon substances simultaneously, adding the electrolysis to ozonation (E+-Ozonation) was employed to deal with hazardous activated petroleum waste sludge (P-sludge). It was found that E+-Ozonation could accelerate the ozone utilization and hydroxyl radical (·OH) generation rate. Soluble chemical oxygen demand (SCOD) increased around 16.3 times than the control one (from 471 to 7700 mg/L). The potential carbon source, such as the short-chain carbon of acetate and propionate, increased from 50 to 1088 mg/L and from 27 to 614 mg/L respectively, and approximately accounted for a quarter of total SCOD. Total petroleum hydrocarbon (TPH) decomposition was observed with a much higher removal rate of 84.3% simultaneously, and the substances with the function group of C=C and C-C bonds decomposed greatly. link3 The long- and medium-chain substances in TPH were converted into the short-chain substances (90% of C28-C40 of hydrocarbons was removed, while C10-C18 increased by 13.8%). E+-Ozonation process could be one of the promising methods for P-sludge decomposition through carbon source releasing and TPH removal.The current study investigates the therapeutic and curative effect of Ulva lactuca polyphenolic extract (ULPE) in general and particularly polyphenolics compounds against heavy metal mixture (HME). The toxicity behind heavy metal is due to oxidative stress resulted from heavy metals pollution or administration through contaminated food (vegetables, water, and fish). Heavy metal toxicity plays a major role in different cardiovascular diseases. The objective of this study is aimed to examine the protective effect of ULPE against heavy metal mixture induced cardiovascular diseases through oxidative/antioxidant and inflammatory pathways. Sixty male rats (Sprague-Dawley) were assigned to six groups. link3 Group I served as the control, group II served as the induced group receiving subcutaneously for 7 days 0.25 mg/100 gm body weight/day heavy metal mixtures (Equal concentration of Ni, Cd, Co and Hg chloride, and Pb acetate), group III received (i.p.) ULPE of dose 30 mg for 15 days, group IV served as the protected grou concluded that ULPE possesses a cardiovascular protective agent as a result of highly contents of different bioactive secondary metabolites which have antioxidant as well as free-radical scavenging and anti-inflammatory activates. Showed the mechanism of ULPE as cardioprotective against heavy metal mixture.Cities are usually the final destination for consumable goods and services produced along supply chains and the most appropriate scale to implement policy. Consumption-based policies could complement current carbon emissions mitigation actions, but such studies at the city level are relatively rare. We used a demand-driven input-output model to explore a historical time series (1987-2012) of consumption-based emissions in Tianjin for the first time, a typical industrial city which has the largest carbon footprint in China. The results reveal the differences between consumption- and production-based emissions, and Tianjin has transformed from a producer city into a typical consumer city since 2000s, mainly due to infrastructure construction. There is more capital investment in industrial infrastructures than in real estate in Tianjin, causing the largest carbon footprint. The trade deficit and different carbon intensity have substantial influences on consumption-based emissions. Finally, population, income, and urbanization could enable a more accurate interpretation of urban carbon footprint growth. Demand-driven policy implications for addressing these emissions in booming industrial cities are discussed and provide a new perspective on carbon emissions mitigation. Our results offer valuable lessons on industrial cities' strategies and initiatives for climate change mitigation worldwide, particularly in developing countries.