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The imminent depletion of the Ogallala Aquifer demands innovative cropping alternatives. Even though the benefits of cover crops are well recognized, adoption has been slow in the Southern High Plains (SHP) of the United States because of concerns that cover crops withdraw soil water to the detriment of the summer crops. This small plot experiment tested the interacting effects-production, soil water depletion of the cover crops, and subsequent teff [Eragrostis tef (Zucc.) Trotter] summer hay crops-of irrigation and tillage management with five cover crop types to identify low-risk cover crop practices in the drought-prone SHP. Dryland rye (Secale cereale L.) produced modest forage biomass (>1000 kg ha-1), even in a dry year, but it was found that light irrigation should be used to ensure adequate forage supply (>1200 kg ha-1) if winter grazing is desired. No-till management and timely termination of the winter cover crops were crucial to reducing the negative impact of winter crops on summer teff production. The results indicated no detriment to soil water content that was attributable to planting no-till cover crops compared with the conventional practice of winter fallow. Therefore, producers could take advantage of the soil-conserving attributes of high-quality winter forage cover crops without experiencing significant soil water depletion.The development of disposable sensors that can be easily adapted to every analytical problem is currently a hot topic that is revolutionizing many areas of science and technology. The need for decentralized analytical measurements at real time is increasing for solving problems in areas such as environment pollution, medical diagnostic, food quality assurance, etc., requiring fast action. Despite some current limitations of these devices, such as insufficient detection capability at (ultra)trace level and risk of interferent effects due to matrix, they allow low-cost analysis, portability, low sample consumption, and fast response. In the last years, development of paper-based analytical devices has undergone a dramatic increase for on-site detection of toxic metal ions and other pollutants. Along with the great availability of cellulose substrates, the immobilization of receptors providing enhanced recognition ability, such as a variety of nanomaterials, has driven the design of novel sensing approaches. This review is aimed at describing and discussing the different possibilities arisen with the use of different nanoreceptors (e.g., plasmonic nanoparticles, quantum dots, carbon-based fluorescent nanoparticles, etc.) immobilized onto cellulose-based substrates for trace element detection, their advantages and shortcomings.Epigenetic components are hypothesized to be sensitive to the environment, which should permit species to adapt to environmental changes. In wild populations, epigenetic variation should therefore be mainly driven by environmental variation. Here, we tested whether epigenetic variation (DNA methylation) observed in wild populations is related to their genetic background, and/or to the local environment. Focusing on two sympatric freshwater fish species (Gobio occitaniae and Phoxinus phoxinus), we tested the relationships between epigenetic differentiation, genetic differentiation (using microsatellite and single nucleotide polymorphism (SNP) markers), and environmental distances between sites. We identify positive relationships between pairwise genetic and epigenetic distances in both species. Moreover, epigenetic marks better discriminated populations than genetic markers, especially in G. occitaniae. In G. occitaniae, both pairwise epigenetic and genetic distances were significantly associated to environmental distances between sites. Nonetheless, when controlling for genetic differentiation, the link between epigenetic differentiation and environmental distances was not significant anymore, indicating a noncausal relationship. Our results suggest that fish epigenetic variation is mainly genetically determined and that the environment weakly contributed to epigenetic variation. We advocate the need to control for the genetic background of populations when inferring causal links between epigenetic variation and environmental heterogeneity in wild populations.Objective To identify how Culturally and Linguistically Diverse (CALD) communities are defined in epidemiological research in Australia and provide a definition of CALD status that aids the consistency and interpretability of epidemiological studies. Methods Peer-reviewed literature from January 2015 to May 2020 was searched via four databases (Ovid Medline combined with PubMed, Embase, Emcare, and CINAHL) to identify quantitative studies of CALD people in Australia. Results A total of 108 studies met the criteria for inclusion in the review. Country of birth was the most commonly used CALD definition (n = 33, 30.6%), with combinations of two or more components also frequently used (n = 31, 28.7%). No studies used all the components suggested as core to defining CALD status. including country of birth, languages other than English spoken at home, English proficiency, and indigenous status. Conclusions There was considerable inconsistency in how CALD status was defined. The review suggests that CALD status would best be defined as people born in non-English speaking countries, and/or who do not speak English at home. read more Additionally, indigenous peoples should be considered separately. This recommended definition will support the better identification of potential health disparity and needs in CALD and indigenous communities.Protease-activated receptors (PARs) are a class of G protein-coupled receptors (GPCRs) with a unique mechanism of activation, prompted by a proteolytic cleavage in their N-terminal domain that uncovers a tethered ligand, which binds and stimulates the same receptor. PARs subtypes (PAR1-4) have well-documented roles in coagulation, hemostasis, and inflammation, and have been deeply investigated for their function in cellular survival/degeneration, while their roles in the brain in physiological conditions remain less appreciated. Here, we describe PARs' effects in the modulation of neurotransmission and synaptic plasticity. Available evidence, mainly concerning PAR1-mediated and PAR2-mediated regulation of glutamatergic and GABAergic transmission, supports that PARs are important modulators of synaptic efficacy and plasticity in normal conditions.

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