Russobennetsen1771

Most of the TBI patients 220 (74,3%) were brought to the hospital by private transportation. In-patient treatment was completed in 293 (98.9%) of cases, three (1%) male patients died. In all three cases of lethal outcome, the cause of injury wasroad traffic. Based on existing data, it was possible to study just part of TBI epidemiological properties. TBI national reporting formats do not cover information about location and time of injuries, place of occurrence, therapeutical treatment and severity of the illness. To study the full epidemiological picture of TBI, retrospective studies based on the medical history in hospitals are needed.In this article, we reviewed neurovascular conflicts of most cranial nerves with characteristic clinical syndromes and analyzed preferred treatment strategies, including surgical methods. We conducted literature review using the Pubmed database, selecting articles on cranial nerves compression syndromes, published for 10 years (from 2010 to 2020). The analysis covered all articles with information on the etiology, pathogenesis, clinical findings, diagnosis, differential diagnosis, neuroimaging, and pathomorphological assessment, as well as treatment strategies for such pathology, including surgical methods. After identifying all the articles that met the inclusion criteria and deleting duplicate data, 58 literature sources on cranial nerves compression syndromes associated with neurovascular conflict were selected. Cranial nerves compression syndromes are a complex interdisciplinary problem, often poorly understood and undetectable by neurologists. Literature sources describe cases of neurovascular conflicts with all cranial nerves except for the olfactory one. A blood vessel (an artery, less often a vein), typically in the area where a nerve root exits the brain stem acts as a compressing agent. Clinical findings are diverse and associated with nerve hyperfunction. The most common manifestations are trigeminal neuralgia, glossopharyngeal neuralgia, and hemifacial spasm. Currently, implementation of standard cranial nerve neuroimaging protocol using high-field high-power MR scanners, MR angiography, and DVI tractography into the diagnosis allows to timely detect neurovascular conflict and determine treatment tactics. Neurosurgical intervention should be considered in case of failure or poor tolerance of conservative treatment. In most cases, the operation of choice is microvascular decompression, the essence of which is to separate the compressing vessel from the nerve and insert a sponge between the nerve and the vessel.Metabolism changes play a key role in many mammalian diseases such as decreasing bone mineral density, osteoporosis, digestive disorders. Lactose intolerance is found in 75% of the in human world's population. The aim of this study was evaluation of the genetic aspects of lactase deficiency in different ethnic groups and its relation with pathologies of bone tissue and gastrointestinal tract. The world data of lactose tolerance, hip fracture incidence, digestive diseases were derived from websites the International Osteoporosis Foundation and World Health Organization. Statistical analysis was carried out by Shapiro-Wilk test, Spearman correlation. An analysis of the world population showed that the lactose tolerance parameters have a statistically significant positive correlation with the hip fractures frequency (r=0.656) and a negative correlation with digestion diseases mortality (r=-0.577). An important factor in the pathologies prevention is the diet correction taking into account the phenotype and genotype of lactose tolerance.Difficulties and errors in the treatment of patients with the gout arise, mainly, during urate-lowering therapy. Selleckchem Wnt-C59 The article discusses possible medical errors in acute gouty arthritis and during chronic tophaceous gout in the light of the updated international recommendations of the American College of Rheumatology (ACR) and the European Antirheumatic League (EULAR 2018). As an example of inadequate treatment, the authors describe a case of a patient with chronic tophaceous gout. Errors in the diagnosis and treatment of the patient caused various complications and unjustified surgical intervention - amputation of the right finger and removal of a large tophus in the left forearm. Based on the analysis of mistakes made in the diagnosis and treatment of gout, the authors propose an algorithm for therapeutic tactics in different periods of the disease. So, for the relief of exacerbation in acute gouty arthritis, it is recommended to take the following drugs at starting doses colchicine at a dose of 1.8 mg/day (1. When prescribing urate-lowering therapy, dose titration is necessary, to avoid the development of toxic effects.Gout is a serious medical, social and economic problem of today. The major factor in its pathogenesis is impaired purine metabolism, which leads to an increase in uric acid concentration and the development of monourate-induced inflammation. Disruption of thermoregulation and regional blood flow is an important clinical and pathogenic manifestation of gout, which can be evaluated by the registration of infrared radiation. Comprehensive treatment of patients aimed at different parts of the pathological process, but the effectiveness of enterosorbents in gout has not been investigated. Aim - to study the dynamics of cytokine system in the blood of patients with gout at the inclusion in the complex therapy of carbon enterosorbent "Carboline", as well as to evaluate the change of local temperature above the affected joints by means of thermography. 65 gout patients and 30 healthy people of representative age were examined. All surveyed were divided into two groups, patients of group I received only basic therapy,received carbon enterosorbent with basic therapy. Thermograms reduced the area and intensity of hyperthermia, and the clarity of the contours was lost. The decrease in local temperature was in both groups, but still exceeded the control (p less then 0.05), which indicated subclinical inflammation.The aim of work was to evaluate the efficacy of combination therapy with vitamin D metabolites on mineral bone density and markers of bone remodeling in postmenopausal women with arterial hypertension, obesity and vitamin D deficiency working in adverse environmental conditions. We examined 95 women aged from 48 to 60 years, 79 people (main group) had arterial hypertension, obesity and deficiency vitamin D and worked in adverse conditions of production, 16 were healthy women. The main group depending on the conducted treatment were divided into 3 groups А group - received standard antihypertensive therapy, Cholecalciferol and Alfacalcidol; group B - standard antihypertensive therapy and Cholecalciferol; group C - standard antihypertensive therapy. The examination included anthropometric measurements (body weight, height, calculation of body mass index, waist circumference, hip circumference, calculation of index waist circumference / hip circumference), measurement of blood pressure, laboratory tests - determination of the 25-hydroxyvitamin D, parathyroid hormone, C-terminal telopeptide, osteocalcin, osteoprotegerin, instrumental study of mineral density of bone tissue (the definition of T-criterion).