Rowlandphillips7100
The present study aimed to assess the determinants of waterpipe smoking among women based on a systematic review regarding the increasing prevalence of waterpipe smoking in women and the tendency of them to this type of tobacco.
The present study was a systematic review. The search strategies were based on using a combination of MeSH and free-text terms. Searches were performed inIranian databasesand PubMed, ScienceDirect, Web of Science, EMBASE, Scopus and Medline. Databases inclusion criteria included articles and gray literature in English or Persian, published between January 2000 and December 2018. selleck chemical The keywords were related to women and waterpipe and related terms. The quality of the articles was assessed using the EPHPP tool.
In the initial search, out of 1027 articles, 15 articles were studied. Inclusion criteria in this study were the target population of women and girl and descriptive and qualitative studies on waterpipe use among women. The mean prevalence of waterpipe smoking in quantitative ere is a necessity to act and impose interventions such as lessening women's favorable attitude toward waterpipe, increasing women's awareness, encouraging negative prototype about waterpipe smoking, and restricting access to tobacco products that can be useful. Interpersonal factors such as the role of family and friends are one of the major determinants in waterpipe smoking. It seems that developing the skill of saying "no" to the pressure of friends can help prevent waterpipe use. Furthermore, educating the family about the risks of waterpipe use is an effective strategy in this respect.
This systematic review was conducted to review the studies investigating the role of dietary approach to stop hypertension (DASH) diet in prevalence and progression of the metabolic syndrome (MetS) in children, adolescents, and adults.
Electronic searches for included studies were performed in MEDLINE, SCOPUS, EMBASE, Cochrane Trial Register, and ISI Web of Science until 30 March 2020. Study selection, data extraction, and quality assessment were fulfilled independently by two reviewers using predefined criteria. Studies were included if they assessed the role of adherence to DASH diet in risk of incidence, prevalence, and development of MetS.
Twelve eligible studies (eight observational studies and four clinical trials) were identified. Despite methodological heterogeneity, limited statistical power, and the cross-sectional nature of most of observational studies, greater adherence to DASH diet was associated with reduced risk of MetS. However, results for change in metabolic characteristics based on dietary intervention with DASH diet in some interventional studies were somewhat controversial.
The current study demonstrates that, based on observational studies, greater adherence to a DASH diet is inversely associated with MetS presence and progression. However, more interventional studies are needed in this regard to clarify the exact effect of DASH diet on MetS.
The current study demonstrates that, based on observational studies, greater adherence to a DASH diet is inversely associated with MetS presence and progression. However, more interventional studies are needed in this regard to clarify the exact effect of DASH diet on MetS.
Carbapenem-resistant
(CRAB) is considered highly virulent due to csgA gene-mediated biofilm formation. The present study aimed to target the same gene, employing the antibiofilm effect of
(
) essential oil compounds among CRAB strains.
A semi-quantitative adherent bioassay was performed to detect the biofilm formation in 73 CRAB strains. This was followed by molecular characterization, Polymerase Chain Reaction (PCR) amplification, and
gene sequencing. An antibiofilm assay under in vitro conditions, with essential oils of
was performed. This was followed with further docking analysis of csgA protein with the selected compounds from the
essential oils. A Molinspiration assessment was also done to elicit the drug likeliness of the biocompounds.
The biofilm assay showed 58.9% as high-grade and 31.5% as low-grade biofilm formers, while 9.58% were non-biofilm formers. Molecular characterization of the
gene showed 20.54% (15/73) positivity. The strains that were imipenem resistant also showed the
gene to be present (100%; 15/15), with 60% (9/15) and 20% (3/15) for meropenem and doripenem resistance respectively. A crystal violet assay for determining cell viability was done in vitro, which gave Minimum biofilm inhibition concentrations of 50% (MBEC50) at 25 µl and 90% (MBEC90) at 50 µl. The docking analysis done
showed benzofuran to possess the lowest binding energy and highest hydrogen bond interactions.
The results indicate benzofuran, from the
essential oils, to be effective in targeting the
gene among CRAB strains. Additionally, validation of these findings through
studies is required.
The results indicate benzofuran, from the O. sanctum essential oils, to be effective in targeting the csgA gene among CRAB strains. Additionally, validation of these findings through in vivo studies is required.
Use of chemical anti-cancer drugs frequently creates serious side effects. However, probiotics are natural and treat different kinds of cancer without undesired effects.
In this study, a nano delivery system was planned to transport the
GG (L. GG) cytoplasmic fraction (Cf) to cancerous tissue in a mouse model. Magnetic iron nanoparticles (MINPs) were synthesized and loaded with L. GG-Cf(0, 0.312, 0.625, 1.25, and 2.5 mg/ml) and were administrated for three weeks to treat experimentally induced murine breast cancer in a constant magnetic field. At the end of the trial, the treating efficacy of this complex molecule was evaluated via western blotting, immunohistochemistry, and qPCR.
Results showed that MINPS can deliver and accumulate L. GG-Cf in cancer tissue, and reduce the size and volume of the tumors. Additionally, in cancer tissues of treated mice with 2.5 mg/ml of Cf-MINPs, significantly induced apoptosis was seen compared with untreated mice (control), and our data proved that this induction may be due to the caspase-3 pathway.
