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Harmful cyanobacterial blooms (cyanoHABs) pose threats to human and animal health due to the production of harmful cyanotoxins. Microcystis aeruginosa is a common cyanobacterium associated with these blooms and is responsible for producing the potent cyclic hepatotoxin microcystin-LR (MC-LR). Concerns over the public health implications of these toxins in water supplies have increased due to rising occurrence of these blooms. High energy electron beam (eBeam) irradiation technology presents a promising strategy for the mitigation of both cyanobacterial cells and cyanotoxins within the water treatment process. However, it is imperative that both cellular and chemical responses to eBeam irradiation are understood to ensure efficient treatment. We sought to investigate the effect of eBeam irradiation on M. aeruginosa cells and MC-LR degradation. Results indicate that doses as low as 2 kGy are lethal to M. aeruginosa cells and induce cell lysis. Even lower doses are required for degradation of the parent MC-LR toxin. However, it was observed that there is a delay in cell lysis after irradiation where M. aeruginosa cells may still be metabolically active and able to synthesize microcystin. These results suggest that eBeam may be suitable for cyanoHAB mitigation in water treatment if employed following cell lysis.We present a new weakly-compressible smoothed particle hydrodynamics (SPH) method capable of modeling non-slip fixed and moving wall boundary conditions. The formulation combines a boundary volume fraction (BVF) wall approach with the transport-velocity SPH method. The resulting method, named SPH-BVF, offers detection of arbitrarily shaped solid walls on-the-fly, with small computational overhead due to its local formulation. This simple framework is capable of solving problems that are difficult or infeasible for standard SPH, namely flows subject to large shear stresses or at moderate Reynolds numbers, and mass transfer in deformable boundaries. In addition, the method extends the transport-velocity formulation to reaction-diffusion transport of mass in Newtonian fluids and linear elastic solids, which is common in biological structures. Taken together, the SPH-BVF method provides a good balance of simplicity and versatility, while avoiding some of the standard obstacles associated with SPH particle penetration at the boundaries, tension instabilities and anisotropic particle alignments, that hamper SPH from being applied to complex problems such as fluid-structure interaction in a biological system.This article considers the intersection of multiple and, at times, seemingly conflicting temporalities in Andean childhoods. We draw on Silvia Rivera Cusicanqui's scholarship on Andean sociology and our ethnographic research with Cañari families to argue that Cañari families' and children's relations with cows and milk production are fueled by both capitalist and Andean temporalities that cannot be thought as opposites. These temporal relations do not create confusion or limiting binaries but are, we propose, itinerant. We show how Cañari children's and cows' collective lives are knitted within ch'ixi temporalities.Students have been multiply impacted by the COVID-19 pandemic threats to their own and their family's health, the closure of schools, and pivoting to online learning in March 2020, a long summer of physical distancing, and then the challenge of returning to school in fall 2020. As damaging as the physical health effects of a global pandemic are, much has been speculated about the "second wave" of mental health crises, particularly for school-aged children and adolescents. Yet, few studies have asked students about their experiences during the pandemic. The present study engaged with over two thousand (N = 2,310; 1,288 female; M age = 14.5) 12- to 18-year-old Alberta students during their first few weeks of return-to-school in fall 2020. Students completed an online survey that asked about their perceptions of COVID-19, their fall return-to-school experiences (84.9% returned in-person), their self-reported pandemic-related stress, and their behavior, affect, and cognitive functioning in the first few weeks of Research on glass cliff political candidacies shows that compared to men, women are more likely to run for office in districts where they are likely to lose. We examined if party differences in whether female candidates face these worse conditions in the United States could account for persistent and growing party and state variation in women's representation. Using election data from 2011 to 2016, we compared Republican versus Democratic candidacies at the state legislative level. We found that women in both parties faced glass cliffs in House races, but not in the Senate. For Republican women, glass cliff conditions accounted for worse election outcomes, but Democratic women were more likely to win when these conditions were considered. Variation in party by state measures of glass cliff effects were also found to explain state variation in women's office holding. We found that for Democrats, more women win when more women run, but for Republicans, more women win only when the seats they face are more winnable. These results point to the role of polarized traditional versus progressive political ideologies in structuring the motives which underlie glass cliff conditions for women in politics, suggesting that practical solutions be tailored to party. To overcome the growing gap in women's representation, current efforts to increase the quantity of women running would be complemented by a focus on improving the quality of contests they face, with Republican women most likely to benefit. Further research attending to the multiple sources of variation which impact gendered election outcomes can inform more targeted solutions for advancing equality. Etomoxir CPT inhibitor Online slides for instructors who want to use this article for teaching are available on PWQ's website at http//journals.sagepub.com/doi/suppl/10.1177/0361684321992046.The growth of mobile workforces to support diversified resource extraction activities, compared to historically single-industry towns, represents a key change in rural and remote resource landscapes that has accelerated since the 1980s. Mobile workforces can present many opportunities to rural communities and economies. However, the capacity, viability and competitiveness of rural-based businesses to engage in supply chains serving mobile labour may be undermined by limited attention to how businesses manoeuvre downturns while maintaining a level of readiness to recover and scale-up in order to meet emerging mobile workforce needs. Drawing upon interviews with businesses in Fort St. John, British Columbia, Canada, our research uses the concept of resiliency to examine challenges and strategies associated with business capacity and agility to scale-up and scale-down in response to changing economic conditions associated with large-scale mobile workforces and related economic sectors. Our findings suggest that the capacity to scale-up and scale-down is shaped by capital, human resource and infrastructure strategies, inventory management and contract management strategies.

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