Romanfischer7884

Comparing to the previously established models, we achieved high prediction accuracy, fitness, and robustness by only using freeware. Therefore, our developed QSPR models can be useful for preliminary risk assessment in the early developmental stages of pesticides. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.AIM General movements assessment (GMA), based on Gestalt perception, identifies infants at risk of cerebral palsy. However, the requirement of ample experience to construct the assessor's inner criteria for abnormal movement hampers its widespread clinical use. This study aims to describe details of general movements (GMs) in various body parts and to investigate their association with GMA-Gestalt. METHODS Participants were 24 typically developing infants and 22 very-high-risk infants. GMs were assessed during the writhing (0-8 weeks) and/or fidgety GM-phase (2-5 months) by GMA-Gestalt and a semi-quantification of the duration of simple movements and complex movements in various body parts. RESULTS During both GM-phases, the quality of movement often varied within a single assessment, but the degree of complexity and variation of movements in trunk, arms, and legs were interrelated (ρ=0.32-0.84). Longer durations of complex movements in arms and legs (p less then 0.042) were further associated with a better quality in GMA-Gestalt. Head movement was associated with movements in other body parts only in the writhing phase and not associated with GMA-Gestalt during both GM-phases. CONCLUSION Infants did not show consistently over time and across body parts simple or complex movements. Detailed description of movement characteristics may facilitate the development of computer-based GMA. This article is protected by copyright. All rights reserved.BACKGROUND Tooth wear is a multifactorial condition, leading to the loss of dental hard tissues. Physiological tooth wear is a slow process that normally does not lead to any subjective symptoms. When the condition progresses, it can become pathological, and several signs and symptoms may occur. The Tooth Wear Evaluation System (TWES) was described to implement a systematic diagnostic and management approach. Recently, management guidelines were presented in a European Consensus Statement (ECS) as well. OBJECTIVES To evaluate the TWES in practice and to integrate the principles described in the ECS in order to compose a renewed TWES 2.0 and a new taxonomy. METHODS The TWES and the recommendations of the ECS were used by dental clinicians, in order to test its applicability in practice. RESULTS Agreement was reached that the TWES 2.0 will use a stepwise approach, with a straightforward Tooth Wear Screening part and a more detailed Tooth Wear Status part. Also, the assessment of pathology from the ECS is incorporated in the TWES 2.0 (both classification and taxonomy). CONCLUSIONS In the TWES 2.0 is described that tooth wear is pathological if moderate/severe/extreme tooth wear is present, in combination with one or several described signs and symptoms. Etiology can be assessed by findings that indicate a chemical and/or a mechanical cause. read more The taxonomy may help to identify situations in which preventive (restorative) interventions in early stages of tooth wear can be indicated. The reliability and validity of the adapted parts must be proven. This article is protected by copyright. All rights reserved.AIM To compare incidence of urolithiasis in second-generation immigrant children aged 0-17 years to children of Swedish-born parents. METHODS A nationwide study of individuals residing in Sweden. Urolithiasis was defined as having at least one registered diagnosis of urolithiasis in the Swedish National Patient Register between January 1, 1998 and December 31, 2015. Cox regression analysis was used to estimate the relative risk (hazard ratios (HR) with 95% confidence intervals (CI)) of incident urolithiasis compared to individuals with Swedish-born parents. The models were stratified by sex and adjusted for age, co-morbidities and sociodemographic status of parents. RESULTS Totally, 1653 incident cases of urolithiasis were registered, 658 boys and 995 girls, with a mean annual incidence per 100 000 person-years for children with Swedish-born parents of 4.0 (95% CI 3.7-4.3) in boys and 6.7 (95% CI 6.2-7.2) in girls, and for children with foreign-born parents of 5.3 (95% CI 5.1-5.4) in boys and 7.2 (95% CI 6.9-7.4) in girls. The fully adjusted HRs of urolithiasis in second-generation immigrants were non-significant, in boys (1.20, 95% CI 0.99-1.46) and girls (0.95, 95% CI 0.80-1.12). CONCLUSION The risk of urolithiasis in second-generation immigrants was not significantly different from that of children with Swedish-born parents. © 2020 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica.In a laboratory experiment we investigated the effects of pesticide mixtures on the structure and function of freshwater biofilms, with focus on their photoautotrophic component. We identified 6 herbicides and 1 fungicide commonly found in Swedish streams at relatively high concentrations and created three ternary mixtures that were tested in concentration series ranging from observed environmental concentrations to up to 100 times higher. Biofilms were exposed to these pesticide mixtures for 8 days and then allowed to recover for another 12 days. Our results show a rapid and consistent inhibition of photosynthesis after just 24 h exposure to the highest test concentration of pesticides, as well as in some treatments with lower concentrations (i.e., 10x the environmental level), upon exposure. Interestingly, the observed effects were reversible, as biofilm photosynthesis recovered rapidly and completely in clean media in all but one treatment. In contrast to the functional response, no effects were observed on the algal assemblage structure, as assessed by diagnostic pigments. We conclude that the pesticide mixtures induce a rapid but reversible inhibition of photosynthesis, without short-term effects on biofilm structure. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.