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The ways of further improvement of the procedure of conducting expert studies of genital mutilation as a characteristic feature of bodily harm, which facilitates avoiding of errors in forensic medical and judicial practices have been found. The process of criminalization of the illegal conduct of surgical operations, resulted in mutilation of genitalia, must take place with the mandatory involvement of specialists in the field of practical medicine, as well as medical scientists specializing in sexopathology, gynecology, oncogynecology, forensic medicine in order to avoid errors in the lawmaking.OBJECTIVE The aim of our study was to determine features of social and emotional intelligence in family caregivers of patients with endogenous mental disorders as a basis for communicative resource formation in family where a patient lives. PATIENTS AND METHODS Materials and methods A total of 273 family caregivers of patients with paranoid schizophrenia and bipolar disorder were involved into this survey under informed consent conditions. https://www.selleckchem.com/products/cb-839.html Control group included 55 mentally healthy respondents, in whose families there is no mentally sick family member. Emotional intelligence of family caregivers was measured using the psychodiagnostic test "EQ" by N. Hall. To assess level of social intelligence the J. Gilford and M. Sullivan test (in adaptation done by Mikhailova E.S.) was used. Values of p less then 0.05 were considered significant. RESULTS Results The study revealed that family caregivers of patients with schizophrenia and affective disorders demonstrate a decrease in emotional and social intelligence indicators, which creates significant obstacles for effective interpersonal family communication and for the harmonious functioning of a family, in which a mentally sick patient lives, in general. Difficulties of emotional regulation, emotional management, recognition of emotional states of other participants of communication related to the level of emotional and social intelligence of FC are factors, that complicate interpersonal relations in families of patients and reduce possibilities for psychosocial adaptation of all family members. CONCLUSION Conclusions Revealed features should be taken into consideration when creating appropriate psycho-educational and psycho-corrective programs for family caregivers of patients with endogenous mental disorders.OBJECTIVE The aim was to examine intraocular pressure (IOP) during lumbar spine surgery in PP under general vs spinal anesthesia and to compare it with volunteers in PP. PATIENTS AND METHODS Materials and methods We performed randomized prospective single institutional trial. Patients were operated in PP with fixation of 1-2 spinal segments. Patients of group I (n = 30) were operated under SA, group 2A (n = 25) - under TIVA (total intravenous anesthesia) with 45° head rotation (left eye was located lower, than right eye), group 2B (n=25) - under TIVA with no head rotation (both eyes were located on the same level). IOP was measured with Maklakov method before and after surgery. Volunteers (n = 20) were examined before and 90 minutes after lying in PP with 45° head rotation. RESULTS Results In all patients and volunteers after lying in PP, we found that IOP have increased. In SA patients and in TIVA patients with no head rotation there was no difference between eyes. The most significant raise of IOP was found in the dependent eye of IIA group patients it was higher than in volunteers and I group patients (p less then 0.01), and IIB group patients (p less then 0.05). In SA patients there was no difference in IOP comparing to volunteers. CONCLUSION Conclusions IOP increased in PP in healthy people and patients under anesthesia (SA and TIVA). IOP in SA patients did not differ from volunteers. IOP increased superiorly in the dependent eye in TIVA patients.OBJECTIVE The aim to study and compare the features of the interleukins levels and morphological changes of placenta at various stages of preeclampsia. PATIENTS AND METHODS Materials and methods 109 pregnant women with preeclampsia of varying severity (study group) and 30 pregnant women with uncomplicated pregnancy (control group) were examined. Immunohistochemical method, proinflammatory interleukins levels, morphological and morphometric analysis of peripheral and central placental areas biopsies on the optical and electron-microscopic level have been used. RESULTS Results Morphofunctional changes in the placenta in case of preeclampsia and the increase in the expression level of the transforming growth factor have a series of regular stages from the formation, strain and disruption of adaptive mechanisms with more pronounced signs of morphological immaturity of parenchymal and stromal elements of the placenta, especially in the area of syncytiotrophoblast and spiral vessels. The degree of clinical manifestation of preeclampsia has a correlation relationship with IL-10 deficiency and with the increase in TNF-α, stimulation of macrophage-protein production that contributes to the change in the ratio of Thl / Th2, which are antagonists and inhibit each other's development. CONCLUSION Conclusions The severity of the preeclampsia course correlates with the state of morphofunctional changes in the placenta and changes in the ratio of the pro- and anti-inflammatory interleukins.OBJECTIVE The aim the analysis of the PD, pregnancy, the labor, the research on peculiarities of the development and health status of breast-fed children, who are born to mothers with PD, by means of analyzing the mother-child pair's nutritional status and mineral homeostasis. PATIENTS AND METHODS Materials and methods At the 1 stage, an analysis of the PD frequency, the pregnancy, the labor was conducted during 5 years. At the 2 stage, 188 mother-child pairs were examined 84.04% women had PD and 15.96% didn't have it. The research included the analysis of the anamnestic data, maternal nutritional status, general clinical study, assessment of the physical, psychomotor level of the child's development, study of the elemental profile. RESULTS Results High frequency of complications in pregnancy and labor was observed in cases when women had PD, due to the imbalance in the "mother-placenta-fetus" system. The results' analysis showed an increased level of Zn (1.437%), K (10.147%), and Ca (83.900%) in hair; an increased level of K (82.

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