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It also potentially offers the prospect of calculating individualized therapeutic administered activities to enhance efficacy and limit toxicity. In this review, we present an overview of the regulation of RAI uptake and clinically investigated redifferentiation agents, both reimbursed and in experimental setting, that induce renewed RAI uptake. We describe the role of dosimetry in redifferentiation and subsequent I-131 therapy in RAI-R thyroid cancer, explain different dosimetry approaches and discuss limitations and considerations in the field.

Considering the great need for palliative care in hospitals, it is essential for hospital staff to have palliative care knowledge. Palliative consultations have been shown to have positive effects on in-hospital care. However, barriers to contact with and uptake of palliative consultation advice are reported, posing a need for further knowledge about the process of palliative consultations. The purpose of this study therefore was to examine how palliative consultations in hospitals are practised, as perceived by consultants and health care professionals on receiving wards.

Focus groups with palliative care consultation services, health care personnel from receiving wards and managers of consultation services. Interpretive description and constant comparative method guided the analysis.

Variations were seen in several aspects of practice, including approach to practice and represented professions. The palliative consultants were perceived to contribute by creating space for palliative care, adding palliah is useful when designing and starting new consultation services.

To analyze clinical studies on correlations between Traditional Chinese Medicine (TCM) body constitution types and diseases published in the past 10 years, and to provide an evidence base to support the use of such correlations for health maintenance and disease prevention.

We searched five databases for the period April 2009 to December 2019 China National Knowledge Infrastructure Database, Wanfang Database, China Science and Technology Journal Database, PubMed and Embase. Three types of observational studies on correlation between constitution types and diseases were included cross-sectional, case-control and cohort studies. Descriptive statistical methods were employed for data analysis.

A total of 1639 clinical studies were identified 1452 (88.59%) cross-sectional studies, 115 (7.02%) case-control studies and 72 (4.39%) cohort studies covering 30 regions of China and five other countries (Malaysia, South Korea, Singapore, Thailand and France). The collection of studies comprised 19 disease categorie, endometriosis and stroke; Qi-stagnation constitution in hyperplasia and neoplasms of the breast, insomnia, depression and thyroid nodules; and inherited-special constitution in asthma and allergic rhinitis.

Eight biased TCM constitutions were closely related to specific diseases, and could be used to guide individualized prevention and treatment. More rigorously designed studies are recommended to further verify the constitution-disease relationship.

Eight biased TCM constitutions were closely related to specific diseases, and could be used to guide individualized prevention and treatment. LY2603618 ic50 More rigorously designed studies are recommended to further verify the constitution-disease relationship.

To investigate the effect of Bushen Jianpi formula (BSJP) therapy on survival of the patients with moderate and advanced hepatocellular carcinoma (HCC).

This was a five-year retrospective study, enrolling 209 adult patients with moderate and advanced HCC patients. Log-rank test, Cox regression analysis and Kaplan-Meier analysis was applied to analyze the data.

The outcome of single-factor Kaplan-Meier analysis and Log-rank test showed that stage of Barcelona-clinic liver cancer (BCLC), locoregional therapy and BSJP therapy were three factors that dominantly influenced the survival of moderate and advanced HCC patients (P < 0.05). In Cox multiple-factor regression analysis, lower BCLC staging (RR = 2.016; P = 0.000), locoregional therapy (RR = 0.611; P = 0.011) and BSJP therapy (RR = 0.684; P = 0.044) were the independent protective factors affecting survival of patients, and BSJP exerted a more significant effect on patients at BCLC-C stage (RR = 0.513; P = 0.002).

BSJP therapy and locoregional therapy both contributed to prolonged survival for moderate and advanced HCC patients.

BSJP therapy and locoregional therapy both contributed to prolonged survival for moderate and advanced HCC patients.

To evaluate the effects of Qizhukangxian granules (QG) on idiopathic pulmonary fibrosis (IPF).

This is a randomized, double blind, placebo-controlled and multicenter clinical pilot trial. Six medical centers in Tianjin, China, participated in the study. A total of 120 IPF patients were enrolled and randomized into two groups, with 60 patients in each group. The treatment group was treated with QG, while the control group received a Qizhukangxian placebo. The pharmacological treatment lasted for 48 weeks from the enrollment date. The indexes of patients were recorded on the admission day and at the end of the 24th and 48th weeks. Data were analyzed to study the effects of QG; forced vital capacity, change in forced vital capacity and maximal 6-min walk test (6MWT) distance were the primary endpoints. Secondary endpoints were percentage of patients with episodes of acute exacerbation of IPF, pulmonary function, changes in pulse oxygen saturation during the 6MWT, dyspnea score, St. George's respiratory questreat IPF patients by ameliorating pulmonary function, improving the quality of life and lowering the percentage of acute exacerbations.

To evaluate the clinical efficacy and safety of Rebixiao (RBX) Chinese herbal tablets (CHT) and Chinese formula granules (CFG) in the treatment of acute gout arthritis (AGA).

This randomized, multicenter, double-blind, controlled trial included 165 AGA patients with the damp-heat symptom pattern who were randomly divided into an RBX CHT group and an RBX CFG group and treated for 7 d at three centers. The total effective rates of the joint symptom score, Traditional Chinese Medicine (TCM) symptoms score, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) were used to evaluate the clinical efficacy. Safety assessments were also performed.

Of the 165 enrolled patients, 147 completed the clinical observation. There was no difference in baseline between the two groups. The total effective rates of the joint symptom score were 94.36% and 97.36%, and the total effective rates of the TCM symptoms score were 95.77% and 97.36% in the CFG group and CHT group, respectively. No statistical difference was found between the two groups (P > 0.