Ringfeddersen3509

Local hypoxia at the site of B. cinerea infection allows the stabilization of ERF-VII proteins. Hypoxia at the site of pathogen infection generates a nearly oxygen-free environment that may affect the stability of other N-degron-regulated proteins as well as the metabolism of elicitors. This article is protected by copyright. All rights reserved.The Organ Procurement and Transplantation Network recently approved liver transplant (LT) prioritization for patients with hepatocellular carcinoma (HCC) beyond Milan Criteria (MC) who are downstaged (DS) with locoregional therapy (LRT). We evaluated post-LT outcomes, predictors of downstaging, and the impact of LRT in beyond-MC HCC patients from the US Multicenter HCC Transplant Consortium (20 centers, 2002-2013). Clinicopathologic characteristics, overall survival (OS), recurrence-free survival (RFS), and HCC recurrence (HCC-R) were compared between patients within MC (n=3,570) and beyond MC (n=789) who were downstaged (DS, n=465), treated with LRT and not downstaged (LRT-NoDS, n=242), or untreated (NoLRT-NoDS, n=82). Five-year post-LT OS and RFS was higher in MC (71.3% and 68.2%) compared to DS (64.3% and 59.5%), and lowest in NoDS (n=324; 60.2% and 53.8%; overall P12 months. LRT-NoDS had greater HCC-R compared to NoLRT-NoDS (34.1% vs 26.1%,P less then 0.001), even after controlling for clinicopathologic variables (HR=2.33,P less then 0.001) and inverse probability of treatment weighted propensity matching (HR=1.82,P less then 0.001). Conclusion In LT recipients with HCC presenting beyond MC, successful downstaging is predicted by wait time, alpha-fetoprotein response to LRT, and tumor burden, and results in excellent post-LT outcomes, justifying expansion of LT criteria. In LRT-NoDS patients, higher HCC-R compared to NoLRT-NoDS cannot be explained by clinicopathologic differences, suggesting a potentially aggravating role of LRT in patients with poor tumor biology that warrants further investigation. This article is protected by copyright. All rights reserved.OBJECTIVE To translate and cross-culturally adapt the Craniofacial Pain and Disability Inventory (CF-PDI) into Chinese and, to evaluate measurement properties of the web-based version of the CF-PDI. METHODS The Chinese version (CF-PDI/C) was first produced according the guidelines. Then, the web-based version of CF-PDI/C (eCF-PDI/C) was developed by our team and a third-party survey provider. The eCF-PDI/C was distributed to patients with painful temporomandibular disorders (TMD) with or without headache to evaluate its psychometric properties. The reliability of the eCF-PDI/C was detected by internal consistency and test-retest reliability. The validity of the measure was performed through construct validity and convergent validity. RESULTS A total of 206 patients were recruited. Eloxatin The Cronbach's α value and the intraclass correlation coefficients (ICC) value of the eCF-PDI/C was .912 and .82, respectively. Following exploratory factor analysis (EFA), three factors were extracted, accounting for 77.153% of the total variation. With regard to the convergent validity, the measure evidenced a good relationship with the global health question. CONCLUSIONS The eCF-PDI/C displays good reliability and validity through rigorous performance tests. This can be recommended for use among patients with painful TMD with or without headache. © 2020 John Wiley & Sons Ltd.Hexavalent chromium in cement 5-8 mg/kg hexavalent chromium (Cr(VI)) was found in Honduran cement samples, which was slightly higher than in Swedish samples. Variable amounts of Cr(VI) (0.4 and 4.7 mg/kg) found in Swedish cement samples that were older than 1 year. There are still many countries that do not have a compulsory reduction of Cr(VI) in cement. Several measures can be employed to reduce risks related to Cr(VI) in cement. © 2020 The Authors. Contact Dermatitis published by John Wiley & Sons Ltd.BACKGROUND Yerba mate extract was encapsulated in electrospun zein fibers. Solutions were prepared with 30% (w/v) zein, and yerba mate extract was added at concentrations of 1%, 3%, and 5% (w/w). The rheology and electrical conductivity of the polymer solutions were evaluated. The extract and the fibers were characterized through an analysis of total and individual phenolic compounds, antioxidant activity, and Fourier-transform infrared (FTIR) spectra. Morphology, size distribution, and thermal stability were also evaluated. The release kinetics of zein fibers loaded with different concentrations of yerba mate were evaluated in a hydrophilic food-simulant medium (10% ethanol). RESULTS Yerba mate extract had a total phenolic compound content of 1287.76 ± 11.55 mg of gallic acid 100 g-1 yerba mate extract. The major individual phenolic compounds obtained were chlorogenic acid and rutin, quantified by high-performance liquid chromatography and mess spectrometry (HPLC-MS). Zein fibers loaded with 5% extract exhibited higher antioxidant activity with 83.0% inhibition. The fibers with different concentrations of yerba mate displayed homogeneous morphology. Yerba mate extract encapsulated in zein fibers had greater thermal stability than the free extract. Zein fibers comprising 5% yerba mate extract, when in contact with a hydrophilic food simulant medium, showed a release of approximately 49% of extract within 50 h. CONCLUSION Zein fibers containing yerba mate extract may be used as antioxidant releasers for food packaging. © 2020 Society of Chemical Industry. © 2020 Society of Chemical Industry.BACKGROUND Tea (Camellia sinensis (L.) O. Kuntze) is a hyper-accumulator of fluoride (F). To understand F uptake and distribution in living plants, we visually evaluated the real-time transport of F absorbed by roots and leaves using a positron-emitting (18 F) fluoride tracer and a positron-emitting tracer imaging system. RESULTS F arrived at an aerial plant part about 1.5 h after absorption by roots, suggesting that tea roots had a retention effect on F, and then was transported upward mainly via the xylem and little via the phloem along the tea stem, but no F was observed in the leaves within the initial 8 h. F absorbed via a cut petiole (leaf 4) was mainly transported downward along the stem within the initial 2 h. Although F was first detected in the top and ipsilateral leaves, it was not detected in tea roots by the end of the monitoring. During the monitoring time, F principally accumulated in the node. CONCLUSION F uptake by the petiole of excised leaf and root system was realized in different ways. The nodes indicated that they may play pivotal roles in the transport of F in tea plants.