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Some researches have shown the associations between air pollution and hospital-based emergency department visits, while the evidence about the acute effects of air pollution on emergency ambulance dispatches for the whole population is rarely available, especially on an hourly time scale. This paper aimed to investigate the effects of hourly concentrations of ambient air pollution on hourly number of ambulance emergency call-outs (AECOs) in Shenzhen, China. AECO data were collected from Shenzhen Emergency Center from January 2013 to December 2016. A time-stratified case-crossover design with conditional Poisson regression was performed to fit the relationship between hourly air pollution and AECOs. The distributed lag model was applied to determine lag structure of the effects of air pollutants. There were a total of 502,862 AECOs during the study period. The significant detrimental effects of SO2, PM2.5, and PM10 appeared immediately with a following harvesting effect after 5 h and the effects lasted for about 96 h. The cumulative effect estimates of four pollutants over 0-96 h were 13.99% (95% CI 7.52-20.85%), 2.07% (95% CI 0.72-3.43%), 1.20% (95% CI 0.54-1.87%), and 2.46% (95% CI 1.63-3.29%), respectively. We did not observe significant effects of O3. This population-based study quantifies the adverse effects of air pollution on ambulance dispatches and provides evidence of the lag structure of the effects on an hourly time scale.Filamentous fungi Trichoderma have been able to efficiently degrade fluoroquinolone antibiotics namely ciprofloxacin (CIP) and ofloxacin (OFL) as well as the fungicide climbazole (CLB) that are persistent in conventional activated sludge processes. All targeted compounds were biotransformed by whole cells of Trichoderma spp., exactly T. click here harzanium and T. asperellum, and biosorption played a limited role in their elimination. However, contrasting results were obtained with the two strains. T. asperellum was more efficient against CIP, with a 81% degradation rate in 13 days of incubation, while T. harzianum was more efficient against CLB, with a 91% degradation rate. While in the case of OFL, both strains showed same efficiency with degradation rate around 40%. Adding a cytochrome P450 enzyme inhibitor hardly resulted in the modification of degradation kinetics supporting the implication of extracellular enzymes in chemical biotransformation. Transformation products were identified by liquid chromatography-high resolution-mass spectrometry and transformation pathways were proposed. Biotransformation of selected compounds included hydroxylation, oxidation/reduction and N- and O-dealkylation reactions, similarly to those reported with white rot fungi. CIP underwent transformations at the piperazinyl ring through oxidation and conjugation reactions, while OFL mainly underwent hydroxylation processes and CLB carbonyl reduction into alcohol. Consequently, Trichoderma spp. likely possess a machinery of unspecific enzymes, which makes their application in removal of pharmaceutical and personal care products attractive.Although nonionic surfactant is widely used for petroleum-contaminated soil washing, there is no definite conclusion on the main soil factors which determine the removal of petroleum hydrocarbons from the soil. In this study, the influences of soil properties on Triton X-100-aided soil washing were investigated using 12 soils in China. The sorption characteristic of Triton X-100 on soils was described as well. The sorption isotherms of Triton X-100 on 12 typical soils were fitted to the Langmuir adsorption model, and the maximum sorption amount of Triton X-100 (Qmax) varied from 1.54 to 15.15 mg/g. The removal rates of diesel for 12 soils were well fitted to the modified Michaelis-Menten equation, and the maximum removal rate of diesel (φmax) ranged from 62.92 to 90.36%. The correlation analysis indicated that the φmax is significantly correlated with the Qmax. The soil factors affecting diesel removal from soils followed the order of sand content > cation exchange capacity (CEC) > organic matter (OM) content > silt and clay content > SSA >> pH. The prediction model based on CEC, silt content, and pH explained 83.1% of variance of diesel removal from soils. This study will have important implication for successfully remediating organic-contaminated soil using nonionic surfactant-based soil washing.Agricultural non-point source pollution is one of the important reasons for rural water pollution, and it is also an important source of water eutrophication. In recent years, with the rapid economic growth and social changes in rural areas, large amounts of untreated domestic sewage and agricultural wastewater entering farmland require high efficiency, low operating costs, and minimal maintenance of treatment systems in rural and remote areas to minimize their impact on water and biodiversity. Since there is little research on the ecological treatment technology of agricultural non-point source pollution in China, from the perspective of controlling agricultural non-point source pollution, some ecological treatment technologies suitable for rural areas at home and abroad are summarized. This paper introduces the practical application of ecological treatment technology, the type of process, advantages and disadvantages, and the influencing factors of ecological treatment technology in the purification of sewage engineering and summarizes the removal mechanism of pollutants in ecological treatment technology. Eco-processing technologies are cost-effective in terms of their construction, maintenance, and energy needs and can be considered a sustainable wastewater treatment method, especially in remote areas and developing countries. It provides basic ideas for the construction of rural ecological treatment technology in China and puts forward suggestions and ideas for the future development trend of ecological treatment process sewage.This research investigation proposes a new method for sustainable olive mill wastewater (OMW) treatment and handling. It is based on the combination of its impregnation onto raw cypress sawdust (RCS) followed by electrocoagulation. The retention of OMW compounds onto various RCS doses show an important decrease of its chemical oxygen demand (COD) and its main cation and anion content. The maximum retention efficiencies of COD, Na+, K+, Ca2+, Mg2+, Cl-, [Formula see text], and [Formula see text] were about 51.0%, 75.3%, 28.7%, 77.9%, 84.7%, 41.1%, 98.3%, and 90.9%, respectively, for the highest RCS dose (200 g L-1). This organic matter- and nutrient-loaded biomass could be thermochemically converted through pyrolysis into biofuel and biochar for energetic and agronomic purposes, respectively. The treatment by electrocoagulation of the pre-treated OMW using mild steel electrodes could be considered an attractive treatment method since 75.6% of COD removal efficiency was achieved. Besides, this approach permits a significant energy consumption reduction by 46% as compared with the electrocoagulation process alone. It allows also a significant improvement of the treated effluent quality in terms of both organic and mineral contents that could be reused for the irrigation of olive trees in the context of circular economy.Oleaginous microalgae with high biomass productivity, lipid content, and lipid productivity are desirable for sustainable biofuel production. Rapid and accurate quantification of lipid content facilitates the identification of promising microalgae candidates. In the present study, 23 freshwater microalgae species from river Noyyal were isolated and identified based on their morphological and molecular (18S rRNA) features and recorded as Karunya Algae Culture Collection (KACC). Their biomass and lipid content were characterized and screened using FT-IR, Nile red staining, and gravimetric method. Results generated from FT-IR spectra differentiated KACC microalgae based on their biochemical contents with Scenedesmus rubescens KACC 2 and Chlorococcum sp. KACC 13 possessed high total protein and lipid content, respectively. Nile red fluorescence at 530/575 nm showed the yellow fluorescence under a fluorescent microscope giving the evidence of high neutral lipids in 10 KACC microalgae isolates. Total lipid content showed prominent variation between the KACC isolates and found in the range of 4 to 32% of DW. Lipid productivity and biomass productivity showed a similar pattern among KACC strains. Thus, our findings serve as a baseline data on the bioprospecting potential of KACC isolates from river Noyyal, an unexplored area of Western Ghats.Domestic trade plays a key role in China's rapid economic progress. However, the increased domestic trade causes significant variations in carbon emission transfer among provinces. This study adopted the multi-region input-output (MRIO) model and social network analysis (SNA) to estimate the carbon emission transfer. Furthermore, the carbon emission transfer network characteristics among 30 provinces and 27 sectors were analyzed by using interprovincial input-output tables for 2007, 2010, and 2012. The results showed that (1) Large differences exist in carbon emission transfer flow and its network characteristics between provinces. (2) The three industrial sectors of metal smelting and pressing sector, power, heat production, and supply sector, petroleum processing, coking, and nuclear fuel processing sector have high carbon emission transfer and pose a strong influence on the carbon emission transfer network. (3) Provinces of the eastern region have a "bidirectional spillover" role, while those of the western region have a mediating role as an "agent." Provinces of the central region have a "main inflow" role. Finally, useful policy implications and suggestions of this study are summarized.Proteins and peptides have a great potential as therapeutic agents; they have higher efficiency and lower toxicity, compared to chemical drugs. However, their oral bioavailability is very low; also, the transdermal peptide delivery faces absorption limitations. Accordingly, most of proteins and peptides are administered by parenteral route, but there are many problems associated with this route such as patient discomfort, especially for pediatric use. Thus, it is a great challenge to develop drug delivery systems for administration of proteins and peptides by routes other than parenteral one. This review provides an overview on recent advances adopted for protein and peptide drug delivery, focusing on oral and transdermal routes. This is followed by an emphasis on two recent approaches adopted as delivery systems for protein and peptide drugs, namely aquasomes and microneedles. Aquasomes are nanoparticles fabricated from ceramics developed to enhance proteins and peptides stability, providing an adequate residence time in circulation. It consists of ceramic core coated with poly hydroxyl oligomer, on which protein and peptide drug can be adsorbed. Aquasomes preparation, characterization, and application in protein and peptide drug delivery are discussed. Microneedles are promising transdermal approach; it involves creation of micron-sized pores in the skin for enhancing the drug delivery across the skin, as their length ranged between 150 and 1500 μm. Types of microneedles with different drug delivery mechanisms, characterization, and application in protein and peptide drug delivery are discussed. Graphical abstract.