Pughhuffman6552

To assess differentiating features between bacterial,

, and

skull base osteomyelitis (SBO) with regard to clinical presentation and imaging appearances.

A literature search was performed in April 2020 for studies on SBO with a minimum sample size of 10 patients. Studies that reported presenting symptoms, cross-sectional imaging findings, complications, and mortality were included in the analysis. The quality of included articles was tested using the Quality Assessment of Diagnostic Accuracy Studies 2 tool. A data extraction form was used to retrieve relevant parameters from each of the articles.

Thirteen articles were included in the final analysis. Diabetes mellitus was the most common predisposing factor (12.5-91.0%). Presenting complaints in all bacterial SBO studies were otogenic, while fungal SBO patients had nasal/ocular complaints. Rates of mortality and surgical intervention in the fungal group were 50-100% and 50%, respectively, as compared to the bacterial group - 7-87% and 10%, respectively. On imaging, the site of initial infection in bacterial SBO was the external auditory canal, while in fungal SBO it was the paranasal sinus. The incidence of orbital extension was < 5% in bacterial and 44-70% in fungal SBO, among which

had rates of 65-70%. Bone erosion was less extensive in bacterial SBO, and the patterns differed. The highest incidence of vascular involvement and non-enhancing lesions (23-36%) was seen in

showed highest sino-cranial extension (52-55%) and homogenous bright enhancement.

Systematic analysis of the clinico-radiological parameters in each of the studies revealed differences in presentation, clinical course, extension, bone erosion, and enhancement.

Systematic analysis of the clinico-radiological parameters in each of the studies revealed differences in presentation, clinical course, extension, bone erosion, and enhancement.

To investigate the predictors of intraductal papillary mucinous neoplasms of the pancreas (IPMNs) with high-grade dysplasia, using 2-dimensional (2D) analysis and 3-dimensional (3D) volume-of-interest-based apparent diffusion coefficient (ADC) histogram analysis.

The data of 45 patients with histopathologically confirmed IPMNs with high-grade or low-grade dysplasia were retrospectively assessed. HCQ inhibitor in vitro The 2D analysis included lesion-to-spinal cord signal intensity ratio (LSR), minimum ADC value (ADC

), and mean ADC value (ADC

). The 3D analysis included the overall mean (ADC

), mean of the bottom 10

percentile (ADC

), mean of the bottom 10-25

percentile (ADC

), mean of the bottom 25-50

percentile (ADC

), skewness (ADC

), kurtosis (ADC

), and entropy (ADC

). Diagnostic performance was compared by analysing the area under the receiver operating characteristic curve (AUC). Inter-rater reliability was assessed by blinded evaluation using the intraclass correlation coefficient.

There were 16 and 29 IPMNs with high- and low-grade dysplasia, respectively. The LSR, ADC

, ADC

, ADC

, ADC

, and ADC

showed significant between-group differences (AUC = 72-93%;

< 0.05). Inter-rater reliability assessment showed almost perfect agreement for LSR and substantial agreement for ADC

and ADC

. Multivariate logistic regression showed that ADCoverall mean and ADCentropy were significant independent predictors of malignancy (

< 0.05), with diagnostic accuracies of 80% and 73%, respectively.

ADC

and ADC

from 3D analysis may assist in predicting IPMNs with high-grade dysplasia.

ADCoverall mean and ADCentropy from 3D analysis may assist in predicting IPMNs with high-grade dysplasia.

In our study, we aimed to show the efficiency of diffusion-weighted images at different

-values and apparent diffusion coefficient (ADC) values in the differentiation of recurrent tumours from post-treatment tissue changes.

The conventional and diffusion magnetic resonance images (MRIs) of 42 patients operated for soft tissue sarcomas between June 2012 and March 2015 followed up with MRIs that were evaluated by 2 radiologists retrospectively. Diffusion MRIs were acquired at 4 different

-values (50, 400, 800, 1000 s/mm

). The lesions were classified according to conventional MRI findings as post-treatment changes and recurrent tumours.

When the patient group with recurrent tumours was compared with the patient group with postoperative changes the ADC calculations were statistically significantly lower for the recurrent tumours at all

-levels (

< 0.001 for all

-levels). The sensitivity of

-50 values lower than 3.01 × 10

mm

/s in showing recurrent tumours was 100% and the specificity was 77.78%. The sensitivity of

-400 values lower than 2.1 × 10

mm

/s in showing recurrent tumours was 80% and the specificity was 96.3%. The sensitivity of

-800 values lower than 2.26 × 10

mm

/s in showing recurrent tumours was 100% and the specificity was 88.89%. The sensitivity of

-1000 values lower than 2 × 10

mm

/s in showing recurrent tumours was 93.3% and the specificity was 92.5%.

The ADC values obtained from diffusion-weighted images have high sensitivity and specificity in differentiating recurring soft tissue sarcomas during monitoring after treatment from postoperative changes.

The ADC values obtained from diffusion-weighted images have high sensitivity and specificity in differentiating recurring soft tissue sarcomas during monitoring after treatment from postoperative changes.

Pseudoaneurysms of the common carotid artery secondary to high-velocity fragment injuries to the head and neck in patients are uncommon lesions. Multi-detector computed tomography angiography should be performed on all patients suffering from high-speed fragment injuries of the head and neck.

We share our experience with the endovascular management approach for the closure of 2 separate pseudoaneurysms involving the left common carotid artery.

Numerous options for surgical and endovascular treatment of these lesions are available. Endovascular therapy in patients with common carotid artery pseudoaneurysms offers a reliable and non-invasive management option. It helps in the mitigation of its rupture and thromboembolic complications.

Numerous options for surgical and endovascular treatment of these lesions are available. Endovascular therapy in patients with common carotid artery pseudoaneurysms offers a reliable and non-invasive management option. It helps in the mitigation of its rupture and thromboembolic complications.