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inflammatory and destructive processes in peri-implantitis and in primary and metastatic tumor lesions of the jaws.

Thus, biochemical markers are sensitive indicators of remodeling of bone tissue both in local inflammatory and destructive processes in peri-implantitis and in primary and metastatic tumor lesions of the jaws.

Was to assess the efficacy of Sensodyne toothpast for the improvement of dental hypersensitivity of various origin and the duration of the achieved effect.

We examined 142 patients of which 95 people had tooth sensitivity. Of these, 4 groups were formed homogeneous by age and sex. Group 1 comprised 27 people (average age 34±3 years) with I grade dental abrasion. Group 2 comprised 23 people (average age 33±5 years) with II grade dental abrasion. Group 3 consisted of 23 people (average age 37±4 years) with grade 3 abrasion with gingival recession of varying severity. Group 4 (comparison) comprised 22 people (mean age 36±4 years) with tooth hypersensitivity who were offered a different toothpaste. The severity of hyperesthesia was assessed using the Schiff method.

The study revealed statistically significant decrease in dental sensitivity in all studied groups. The first positive results were noted by day 3. The maximum effect was achieved by day 30 regardless of the etiology of the primary pathology. The hypersensitivity decreased in group 1 from 1.69±0.59 to 0.48±0.20 (by 71.5%), in group 2 from 1.78±0.88 to 0.3±0.22 (by 83.1%), in group 3 from 1.94±0.6 to 0.35±0.17 (by 82%). The duration of the effect obtained was 60 days. In the comparison group, the symptom of hyperesthesia decreased by 51% after 30 days with gingival recession and increased abrasion of hard tissues when using another toothpaste. The achieved effect of reducing hyperesthesia was less stable. At day 60 it decreased by 30% from the maximum value.

The study proved the high efficiency of the Sensodyne toothpaste as a home remedy for symptomatic treatment of hyperesthesia.

The study proved the high efficiency of the Sensodyne toothpaste as a home remedy for symptomatic treatment of hyperesthesia.

The aim of the study was to increase the effectiveness of early diagnosis of dental caries in children.

An epidemiological survey of 678 children (351 of them girls and 327 boys) aged 6-12 years was conducted in the cities of Novorossiysk, Krasnodar Territory (582 people) and Moscow (96 people). By the method of randomization, 450 people were selected, who were divided into three age groups I gr. - 6-7 years; II gr. - 8-9 years old; III gr. - 10-12 years. In each age group, the children were conditionally divided into three subgroups (50 people each) depending on the rate of caries intensity (DMFT=0, DMFT=1-2, DMFT≥3). In children with different indexes of the DMFT, the informativeness of identifying foci of demineralization of the enamel of erupted incisors, molars, canines and premolars was assessed by visual inspection, vital staining and using an apparatus based on the transillumination method.

As a result of an epidemiological survey of children in Moscow, caries prevalence levels were low at 6-7 years old and average at 8-9 and 10-12 years, and in Novorossiysk children low - at 6-7 years and high - at 8- 9 and 10-12 years. Children of 6-12 years old in Moscow have an average level of intensity of caries, and children of Novorossiysk have an average level of 6-7 and 10-12 years, a high level of 8-9 years. During clinical examination of 450 children from 6 to 12 years old, 6.840 permanent teeth were examined. A comparative analysis of the detection of foci of enamel demineralization visually and using the apparatus showed that the apparatus method revealed significantly more teeth with foci of enamel demineralization.

This device can be recommended for use in wide clinical practice, given its efficiency and low cost in comparison with other known devices.

This device can be recommended for use in wide clinical practice, given its efficiency and low cost in comparison with other known devices.

Was to investigate the efficacy of immunomodulatory drug based on muramilpeptides for treatment of chronic generalized periodontitis.

The study group comprised 20 patients aged 25 to 64 with severe chronic periodontal disease. Periodontal pockets content was inoculated for specific microbial pathogens before and after treatment. Twenty patients receiving conventional treatment with no muramilpeptides-based agent served as controls.

In the main group prolonged suppression of periodontal disease provoking microbiota was seen, while in controls conventional treatment was not sufficiently effective resulting in germs growth relapse at day 21.

The dynamics of the microbiological landscape of periodontal pockets after treatment proves the necessity for a correction of innate immunity in inflammatory periodontal disease.

The dynamics of the microbiological landscape of periodontal pockets after treatment proves the necessity for a correction of innate immunity in inflammatory periodontal disease.The purpose of the study was to examine the condition of the pro-antioxidant balance of the homogenates of tissues of the oral mucosal wound surface in vivo experiment under the photodynamic action of combined two-wave radiation to eliminate its damaging effect on the structures of cell membranes.

On the mucous membrane of the cheeks of sexually mature female autocrats of Wistar rats (

=72) experimental models of wound surfaces with a diameter of 3 mm were formed. The animals were divided into groups control (

=36) and experimental (

=36). In the experimental group, a single photodynamic exposure was carried out for the 1st postoperative day with a sequential combined light radiation at two wavelengths (660 nm and 405 nm) with a total dose of 15 J/cm

. Wound management was carried out traditionally in the control group of animals. The observation periods were 3, 7 and 14 days.

Macroscopic examination of the wound surface indicated complete epithelialization of the wound on the 7th day in the experimentss for use on the oral mucous membrane and, may be used to stimulate regeneration of the wound surface, which requires further experimental testing.After 78 years of having been founded, the Mexican Institute of Social Security has undergone several changes in its structure and dimension, secondary to both population growth and epidemiological and social transitions, in such a way that its growth has been exponential. The institute safeguards the welfare of its beneficiaries through medical, economic and social benefits. Currently, it provides health coverage to more than 60% of the Mexican population through the physical infrastructure and workforce of its 440 000 employees.Odontogenic myxoma is a histologically benign and aggressive tumour of the maxillofacial region. It mainly affects young adults and remains exceptional in children. Due to its local invasive nature, it is difficult to differentiate this tumour from malignant neoplasma and from other destructive odontogenic benign tumours. Imaging plays an essential role in the initial exploration and follow-up. Baf-A1 nmr Its management is still a challenge today, due to its aggressive potential and its significant risk of recurrence in children among whom extensive surgical treatment involves significant morbidity in children.Although metastatic lesions associated with small cell lung cancer (SCLC) are rare in the pancreas, metastatic-induced acute pancreatitis from the same cancer is even more so. We discuss the clinical case of a 67-year-old patient with SCLC, diagnosed for 21 months and stable for 3 months, presenting in the emergency department with transfixing epigastric pain. The radiological study reveals two large masses in the pancreas as well as multiple peripancreatic adenopathies. They are confirmed as metastases of the SCLC. Among several treatment proposals, the initiation of palliative analgesia by both radiotherapy and drug therapy is preferred, due to the very advanced state of SCLC and the major toxicity of other systemic treatments.This is a case report of a 13-year old patient presenting with knee pain after a bike accident. Multiple investigations and medical examinations focused on the knee. They did not show any abnormality. About one year later, the patient comes back with increased hip pain, limited internal rotation and shortening of the left limb. Hip X-Ray exams reveal a bilateral slipped capital femoral epiphysis requiring already an osteotomy. Slipped capital femoral epiphysis is a disorder of the proximal femoral epiphysis. The femoral neck is displaced anteriorly and rotates externally while the epiphysis remains in the acetabulum. This pathology is more common in preadolescent boys and can be associated with hormonal disorders. link2 Patients present with an externally rotated gait, a limited internal rotation, associated hip and knee pain. Diagnosis might be missed when patients present with knee pain and can lead to delayed treatment. When facing knee pain, it is essential to perform a clinical examination of the hip. Radiography is the first medical imaging. Surgical treatment by in situ fixation is recommended and prevents further slip with a high rate of success. When delayed, a much more invasive approach is required. A delay in diagnosis adversely affects long-term outcomes.KBG syndrome, named after the initials of the first 3 families reported, is a rare genetic syndrome caused by a deletion or a mutation of ANKRD11 (ankyrin repeat domain-containing protein 11) gene. Its prevalence is probably underestimated because of a variable expressivity; moreover, most of its clinical characteristics are not specific. There is no consensus about its diagnostic criteria. link3 Ophthalmologic manifestations have sometimes been described among more frequent clinical signs. Early detection is critical and multidisciplinary care is requested in order to ensure the patient's independence. We report the case of a 16 years old boy diagnosed with a KBG syndrome after more than one year of genetic research, motivated by a short stature, high refractive errors and bilateral corneal clouding.The occurrence of metabolic acidosis with increased anion gap in the context of chronic paracetamol intoxication is an easily treatable clinical situation. Its rapid recognition is essential given its complete reversibility in the event of adequate management by eviction of the toxic agent, in this case paracetamol. It has an unknown cause and therefore potentially under-diagnosed, to be considered in the same way as the other more frequent etiologies. Because of this lack of knowledge, its frequency is probably underestimated considering the widespread consumption of paracetamol in the population.Intracerebroventricular (ICV) infusion of morphine is a well-known technique to relieve intractable neoplasic pain when conventional analgesic strategies reach their limits. Through this case report, we present indications, assets, and drawbacks of this procedure in such conditions. We also describe the adaptation of the systemic analgesic treatment to allow discharge from the hospital to home settings. Thanks to the ICV infusion of a mixture of morphine, bupivacaine and clonidine, the patient was weaned from oral opioid medications and reached an acceptable level of comfort. This allowed him to be discharged from the hospital to go back home with a specific setting of mobile palliative care structure. The patient's family followed training about the device to prevent any technical trouble and to react in case of unwanted events.

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