Pontoppidanweaver7260

86. The entire instrument demonstrated better psychometric properties than the single sub-scales.Conclusion In this study, the frequency-magnitude of environmental barriers encountered by people post-stroke are reported at a group level and adds information to the cumulative knowledge generation on perceived environmental barriers in the society. However, to inform which interventions are needed at a more detailed level, other data collection methods have to be added.Podcasts and other asynchronous remote learning pedagogies have become increasingly utilized in undergraduate and graduate medical education. They offer a convenient and accessible form of education for personalized learning and have been developed across multiple disciplines of medicine. This paper discusses the current literature on medical education podcasts, offers practical examples of existing free podcast content, and offers guidance on planning, designing, and executing the creation of a new educational podcast. It discusses best practices for the engagement of learners and logistical considerations for recording and hosting the material. These Twelve Tips hope to empower educators to utilize resources across the world to offer the highest quality opportunities for learners of all levels.Purpose The aim was to investigate the systemic levels of cytokines and the expression of the chemokine receptor CXCR2 in circulating neutrophils in patients with non-neoplastic ovarian lesions, benign neoplasia or malignant neoplasia.Materials and methods Controls and patients with ovarian tumours were pre-operatively compared for the production of cytokines (IL-2, IL-5, IL-6, IL-8, IL-10 and TNF-α) by ELISA, and for the expression of the chemokine receptor, CXCR2, in neutrophils, by flow cytometry. Randomly selected patients within the malignant group were re-evaluated for the inflammatory parameters at 30 days after surgery.Results The serum concentrations of IL-6, IL-8 and IL-10 were significantly higher in the benign and malignant neoplasia than in the control group, and their levels were significantly higher in ovarian cancer patients than in patients with non-neoplastic tumours or benign neoplasia. Treatment reduced IL-8 serum levels but did not affect CXCR2 expression in neutrophils. Cut-off values for IL-6, IL-8, and IL-10 comparing malignant vs. benign neoplasia were 11.3, 71.7, 14.8, and comparing malignant neoplasm vs. non-neoplastic lesions were 7.2, 43.5, 12.3, respectively.Conclusions Serum IL-6, IL-8, and IL-10 levels, and expression of CXCR2 in circulating neutrophils seem promising for distinguishing ovarian cancer patients from patients with benign tumours.Objectives Amphotericin-B (d-AmB) has a broader anti-fungal spectrum and is used for neonatal invasive-fungal-infections especially invasive-candidiasis (IC). To prevent d-AmB-induced nephrotoxicity, renal protective effect of fluid and electrolyte management has been established among adults; in this study, the authors determined this effect among neonates. Methods In this retrospective cohort study, the authors reviewed neonatal medical records, admitted to neonatal intensive care unit and received d-AmB therapy. see more Patients were divided into, renal-insufficiency-group (RIG) and the non-renal-insufficiency-group (NIG). Results A total of 90 cases were analyzed, 41 composed RIG and 49 NIG. Renal insufficiency (RI) was developed on 1.7 (0.84) and 7.8 (1.21) days of d-AmB therapy in 26 (63%) and 15 (37%) cases respectively. Bivariate and multivariate analysis demonstrate that >4 m Eq/kg/d sodium intake across all-time points was significantly (p 4 mEq/kg/day sodium intake before and through d-AmB therapy may protect neonatal RI.This study aims to determine the relationship among factors affecting research misconduct within the research system of medical sciences in Iran. Using phenomenography, the perceptions of individuals involved in the activities of macro, meso, and micro levels of the research system were investigated and 13 affecting factors were identified. The DEMATEL method revealed complicated and intertwined relationships among these factors based on the experts' judgment. Most of the macro and meso factors were in the cause group and most of the micro factors were in the effect group. The results showed that critical factors such as "Monitoring and dealing with research misconduct," "Transparency in research," "Management of journals" and "Ethical considerations in the publication of research results" escalate research misconduct. The study indicated that track the relationship among factors in the research system can provide the opportunity to explain research misconduct on a transitional path from macro to micro level.The early diagnosis of cancer at any location of the human body can help in enhancing the survival rate and in reducing the cost of the treatment. Among the several techniques, the conventional infra-red (IR) thermography suffers from several limitations, including higher patient discomfort and longer time for tumour detection based on the temperature difference between tumour and adjacent healthy tissues. Hence, in this work, a novel non-invasive hot stress dynamic IR thermography system is proposed to detect surface tumour without severe discomfort to the patient. The system is designed to detect the surface tumour under 3 min within a temperature range of 42 and 37 °C. A two-dimensional numerical model based on the bio-heat transfer of tissue consists of cancerous and healthy cells is developed and validated to analysis the thermal contrast arises due to the presence of cancerous and healthy cells while cooling naturally. A light source is introduced with appropriate intensity to achieve a suitable temperature contrast. Moreover, the effects of natural convective heat loss from the tissue to the ambient and the scanning speed of IR Thermography on the tissue are investigated. A temperature difference of about 1.5 °C is found after cooling of tissues for 140 s, which can be detected using a thermographic camera. Finally, a sensitivity study is conducted to access the importance of the individual parameter over the final temperature field. The results predict the blood perfusion rate as the most significant parameter that significantly influences the temperature distribution in the considered domain.