Polatmeldgaard9800
35, p=0.02. Multivariable analysis shows a significant association between FDR202 prevalence and log adjusted CAC score in subjects with CAC >0 while adjusting age, gender, hypertension and hyperlipidemia (β=-0.2, SE=0.1, p=0.04). No significant correlations were found between GRS46K, 1.7M, and MetaGRS with CAC score.
Additional research is necessary in a larger population to evaluate the potential role ofGRS for the detection of CAD. This allows the individuals to adopt a healthy lifestyle modificationtominimize the cardiovascular risk and delays the onset of most diseases of old age to prolong the life.
Additional research is necessary in a larger population to evaluate the potential role of GRS for the detection of CAD. This allows the individuals to adopt a healthy lifestyle modification to minimize the cardiovascular risk and delays the onset of most diseases of old age to prolong the life.
Explore the benefits and feasibility of a dual training program for dietetics and nursing to increase nutrition in clinical practice.
A professional interest survey on the perceived value of a dual program with 222 registered nurses (RN) and registered dietitian nutritionists (RDN) and an in-depth literature review were completed.
A majority of RNs indicated the addition of the RDN would be beneficial for supporting patients with diet-related chronic diseases and performing nutritional assessments and interventions. The RDN respondents indicated a dual program approach would also improve the ability to serve a small community or place of employment that is limited in having both a full-time RDN and RN, and rated benefits for performing more medical and laboratory procedures. The RDNs also indicated the dual program could help increase their income potential. Both dual Master's and dual Bachelor's programs were rated as valuable. Of the 18 (8%) of respondents who had both RDN and RN credentials, half indarticularly decreasing time-to-degree while not affecting efficacy.
Myocardial dysfunction is one of the common complications in children with chronic kidney disease which results in significant morbidity and mortality. We aimed to find the impact of anemia with cardiac changes in children with chronic kidney disease (CKD).
In this cross-sectional pilot study, 54 children (38 males) up to the age of 16 years with different stages of CKD, not on dialysis, were enrolled. Cardiovascular functions were evaluated using 2D-echocardiography using EPIC-7 (Philips) machine by an independent trained Pediatric Cardiologist. The M-mode measurements of the left ventricle were measured, indexed for body surface area and z-scores were calculated. They were divided into two groups i. e with and without anemia.
Out of the 54 children with CKD, children with and without anemia were 34 and 20 respectively. The end-diastolic volume was significantly higher in patients with anemia when compared with those without anemia (46.43±16.49ml vs 32.51±4.98ml). The mean left ventricular mass (59.54±23.99 vs 37.24±7.88g) and end-diastolic thickness of the interventricular septum (0.73±0.14 vs 0.54±0.05cm) was significantly elevated in CKD children with anemia.
Left ventricular hypertrophy along with left ventricular dimension and left ventricular diastolic dysfunction was found to be significantly correlating with the degree of anemia. CKD children with anemia should be screened for underlying cardiac dysfunction and appropriate dietary modification and nutritional rehabilitation for iron deficiency should be addressed.
Left ventricular hypertrophy along with left ventricular dimension and left ventricular diastolic dysfunction was found to be significantly correlating with the degree of anemia. CKD children with anemia should be screened for underlying cardiac dysfunction and appropriate dietary modification and nutritional rehabilitation for iron deficiency should be addressed.
The aim of this study was to compare the effect of vitamin D fortified oil consumption and vitamin D supplementation on serum 25-hydroxy vitamin D and bone turnover factors.
This study was a double-blind, parallel, randomized controlled clinical trial conducted over 12 weeks on 93 healthy participants aged 18-30 years. Participants were randomly allocated to 1 of the 3 groups (a) supplement (a tablet of 1000 IU vitamin D supplement+25g canola oil daily, n=31); (b) fortified oil (a placebo tablet+25g canola oil fortified with 1000 IU vitamin D daily, n=30) and (c) control (a placebo tablet+25g canola oil, n=32). Before and after the intervention 25-hydroxy vitamin D (25(OH)D
), parathyroid hormone (PTH
), bone alkaline phosphatase (BAP
) and collagen type 1 cross-linked C-telopeptide I (CTX
) were assessed.
Serum 25(OH)D increased more in the vitamin D supplement group compared to the controls (P=0.001). In addition, subgroup analysis revealed that just in the vitamin D sufficient subgroup, serum 25(n D deficient one. Besides, this dose of vitamin did not have a noticeable effect on bone turnover markers in this period. Registered under Iranian Registry of Clinical Trials (IRCT.ir) with ID number of IRCT20180708040401N1.
Evidence suggests that multiple-behavior interventions (with a specialist) have a greater impact on public health than single-behavior interventions, particularly in a chronic patient. However, there is little understanding of some very basic principles concerning multiple health behavior change, especially in situations such as kidney transplantation, which requires a great willingness to change negative lifestyle behaviors to achieve intermediate and long-term success. We compared healthy lifestyles and nutritional status according to the willingness to change dietary and exercise behavior in dialysis patients from a living donor kidney transplant program.
400 dialysis patients had a dietetic, anthropometric, protein-energy wasting [subjective global assessment (SGA)] and biochemical evaluation. Lifestyle was evaluated with an adapted instrument to measure lifestyle in chronic disease. Willingness to change behaviors was evaluated by the trans-theoretical model; 2 groups were formed willingness to change dietary and exercise behaviors and unwillingness to change.
Willingness to change dietary behavior was 50% and exercise 25%. Patients with willingness to change dietary and exercise behaviors had better healthy lifestyle scores, and higher frequency of healthy food consumption. Healthy lifestyle score (R
=0.37, p<0.0001) was predicted by older age, higher educational degree, shorter time on dialysis, and the highest willingness to change dietary and exercise behaviors.
Willingness to change dietary and exercise behaviors was associated with healthy lifestyle, as well as with higher frequency of healthy food consumption and with lower frequency of unhealthy food consumption.
Willingness to change dietary and exercise behaviors was associated with healthy lifestyle, as well as with higher frequency of healthy food consumption and with lower frequency of unhealthy food consumption.
Several epidemiologic studies have reported that dietary acid load (DAL) is associated with metabolic profiles; however, to our knowledge, the relationship of this dietary pattern with resting metabolic rate (RMR) among obese and overweight females remains unreported. Therefore, this study aimed to evaluate the association of DAL, RMR and metabolic components among overweight and obese adult women.
This cross-sectional study was conducted on 375 Iranian adult women, aged 18-48 years. DAL indices were calculated by using a validated 147-item semi-quantitative food frequency questionnaire. Biochemical and anthropometric measures were assessed using standard methods. An impedance fat analyzer was used to obtain the body composition and an indirect calorimeter was used to assess the RMR.
It was observed that after correction for potential confounders, net endogenous acid production (NEAP) and potential renal acid load (PRAL) scores were inversely associated with diastolic blood pressure (DBP) (P<0.05). NEAP index was inversely associated with RMR (β=-0.44, 95% confidence interval; CI=-1.21 to 0.32, P=0.02), and positively associated with waist circumference (WC) (β=1.04, 95% CI=-1.05 to 4.45, P=0.06) and waist to hip ratio (WHR) (β=0.01, 95% CI=-0.01 to 0.04, P=0.04), such that subjects with higher scores in NEAP had lower RMR and higher WC and WHR. We also observed that NEAP (β=-0.44, 95% CI=-1.21 to 0.32, P=0.02) was significance and PRAL (β=-0.23, 95% CI=-1.50 to 0.47P=0.07) was marginally associated with RMR.
The results of the present study suggested that higher DAL scores may be negatively associated with lower RMR, while directly associated with greater WC, WHR, DBP, and Homeostatic Model Assessment for Insulin Resistance (HOMA-IR).
The results of the present study suggested that higher DAL scores may be negatively associated with lower RMR, while directly associated with greater WC, WHR, DBP, and Homeostatic Model Assessment for Insulin Resistance (HOMA-IR).
Mood disorders such as anxiety, depression, stresses, and low sleep quality are common among overweight/obese women. The relation of vitamin D and its blood carrier, vitamin D binding protein (VDBP), to mental health is still unknown. This study aimed to examine the relation of serum 25(OH)D and VDBP to mental health measures including depression, anxiety, stress and sleep quality of overweight/obese women.
This cross-sectional study included a total of 265 overweight/obese women in Tehran, Iran, from 2016 to 2017. The 21-question version of the Depression Anxiety Stress Scales (DASS-21) and the Pittsburgh Sleep Quality Index (PSQI) were used to evaluate mental health and sleep quality of participants, respectively. Serum 25(OH)D was assessed using the radioimmunoassay method and VDBP was evaluated with the use of ELISA. Associations were tested by logistic regression analysis.
In the crud analysis, higher serum 25(OH)D was marginally related to decreased odds of stress, but, women with higher VDBP levels had a marginal increased risk for depression. After adjustment for age, educational level, physical activity, body mass index and dietary energy intake, higher serum 25(OH)D was significantly related to a 42% decreased odds of stress (OR=0.58, 95%CI 0.28-0.99, p=0.04), while, women with higher VDBP levels had an increased risk for depression (OR=1.74, 95%CI 1.002-3.42, p=0.04). Serum vitamin D and VDBP were not significantly related to other indices of mental health.
Higher serum vitamin D was related to decreased odds of stress but higher VDBP was related to increased odds of depression.
Higher serum vitamin D was related to decreased odds of stress but higher VDBP was related to increased odds of depression.
Sarcopenia was reported to be associated with poor clinical outcome, higher incidence of community-acquired pneumonia, increased risk of infections and reduced survival in different clinical settings. The aim of our work is to evaluate the prognostic role of sarcopenia in patients with the 2019 novel coronavirus disease (COVID-19).
272 COVID-19 patients admitted to the University Hospital of Modena (Italy) from February 2020 to January 2021 were retrospectively studied. All included patients underwent a chest computed tomography (CT) scan to assess pneumonia during their hospitalization and showed a positive SARS-CoV-2 molecular test. Sarcopenia was defined by skeletal muscle area (SMA) evaluation at the 12th thoracic vertebra (T12). Clinical, laboratory data and adverse clinical outcome (admission to Intensive Care Unit and death) were collected for all patients.
Prevalence of sarcopenia was high (41.5%) but significantly different in each pandemic wave (57.9% vs 21.6% p<0.0000). At the multivariate analysis, sarcopenia during the first wave (Hazard Ratio 2.
