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22 logMAR in the right eye and -0.20 logMAR in the left eye. Binocular uncorrected near and intermediate visual acuity were -0.10 logMAR and 0.00 logMAR respectively after exchanging the sulcus-fixated supplementary IOLs, allowing for complete spectacle independence.

This case demonstrates one of the most important benefits of the duet procedure the possibility, if necessary, to easily remove or exchange the supplementary IOL from the ciliary sulcus. The duet procedure offers a safe treatment option in the event of postoperative complications like residual refractive error or intolerance to a multifocal optic.

This case demonstrates one of the most important benefits of the duet procedure the possibility, if necessary, to easily remove or exchange the supplementary IOL from the ciliary sulcus. The duet procedure offers a safe treatment option in the event of postoperative complications like residual refractive error or intolerance to a multifocal optic.Polycystic ovary syndrome (PCOS) is a heterogeneous familial disorder often emerging during the peri-pubertal years concomitantly with the onset of gonadarche and adrenarche. Both gonadarche and PCOS reflect functional changes in the hypothalamic-pituitary-ovarian axis. During this transition, normal girls manifest features consistent with PCOS such as irregular menses, mild hyperandrogenism, and multi-follicular ovary morphology. Themes common to puberty and PCOS, neuroendocrine features, androgen exposure, and insulin sensitivity, will be considered to address the possibility that PCOS interferes with the normal pubertal transition.While most organisms utilize 20 canonical amino acid building blocks for protein synthesis, adding additional candidates to the amino acid repertoire can greatly facilitate the investigation and manipulation of protein structures and functions. In this study, we report the generation of completely autonomous organisms with a 21st ncAA, 5-hydroxytryptophan (5HTP). Like 20 canonical amino acids, 5-hydroxytryptophan can be biosynthesized in vivo from simple carbon sources and is subsequently incorporated into proteins in response to the amber stop codon. Using this unnatural organism, we have prepared a single-chain immunoglobulin variable fragment conjugated with a fluorophore and demonstrated the utility of these autonomous cells to monitor oxidative stress. Creation of this and other cells containing the 21st amino acid will provide an opportunity to generate proteins and organisms with novel activities, as well as to determine the evolutionary consequences of using additional amino acid buildings.Most electrochemical processes are stochastic and discrete in nature. Yet experimental observables, e.g., i vs E, are typically smooth and deterministic, due to many events/processes, e.g., electron transfers, being averaged together. However, when the number of entities measured approaches a few or even one, stochasticity frequently emerges. Yet all is not lost! Probabilistic and statistical interpretation can generate insights matching or superseding those from macroscale/ensemble measurements, revealing phenomena that were hitherto averaged over. Herein, we review recent literature examples of stochastic processes in single-entity electrochemistry, highlighting strategies for interpreting stochasticity, contrasting them with macroscale measurements, and describing the insights generated.The world is going through an unprecedented crisis due to COVID-19 breakout, and people all over the world are forced to stay indoors for safety. In such a situation, the rise and fall of the number of affected cases or deaths has turned into a constant headline in most news channels. Consequently, there is a lack of positivity in the world-wide news published in different forms of media. Texts based on news articles, movie reviews, tweets, etc. are often analyzed by researchers, and mined for determining opinion or sentiment, using supervised and unsupervised methods. The proposed work takes up the challenge of mining a comprehensive set of online news texts, for determining the prevailing sentiment in the context of the ongoing pandemic, along with a statistical analysis of the relation between actual effect of COVID-19 and online news sentiment. The amount and observed delay of impact of the ground truth situation on online news is determined on a global scale, as well as at country level. The authors conclude that at a global level, the news sentiment has a good amount of dependence on the number of new cases or deaths, while the effect varies for different countries, and is also dependent on regional socio-political factors.Online hate speech represents a serious problem exacerbated by the ongoing COVID-19 pandemic. Although often anchored in real-world social divisions, hate speech in cyberspace may also be fueled inorganically by inauthentic actors like social bots. This work presents and employs a methodological pipeline for assessing the links between hate speech and bot-driven activity through the lens of social cybersecurity. Using a combination of machine learning and network science tools, we empirically characterize Twitter conversations about the pandemic in the United States and the Philippines. Our integrated analysis reveals idiosyncratic relationships between bots and hate speech across datasets, highlighting different network dynamics of racially charged toxicity in the US and political conflicts in the Philippines. Most crucially, we discover that bot activity is linked to higher hate in both countries, especially in communities which are denser and more isolated from others. We discuss several insights for probing issues of online hate speech and coordinated disinformation, especially through a global approach to computational social science.[This corrects the article on p. 153 in vol. 5, PMID 32596529.][This corrects the article on p. 165 in vol. 5, PMID 32596530.][This corrects the article on p. 172 in vol. 5, PMID 32782979.][This corrects the article on p. 170 in vol. 5, PMID 32596532.][This corrects the article on p. 167 in vol. 5, PMID 32596531.][This corrects the article on p. 166 in vol. 5, PMID 32782978.][This corrects the article on p. 164 in vol. 5, PMID 32923733.][This corrects the article on p. 192 in vol. 5, PMID 32596534.][This corrects the article on p. 189 in vol. 5, PMID 32954039.][This corrects the article on p. 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