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Foliage photosynthesis and also senescence inside heated as well as droughted field-grown soy bean with contrasting seed health proteins attention.

Extremophiles, a Nifty Instrument to manage Polluting the environment: From Exploitation involving Metabolic process to Genome Engineering.

It is associated with sundry gynecological and obstetric difficulties like abnormal uterine bleeding, pelvic pain, infertility, cesarean scar defect pregnancy or uterine rupture. The most common diagnostic way is using transvaginal ultrasound, sonohysterography or hysteroscopy. Treatment choice is due to a size of cesarean scar defect and also pregnancy planning. Alternatives of treatment including hormonal contraception and various surgery such as hysteroscopy, laparoscopy, laparotomy and transvaginal procedures.

To summarize the possibilities of the genetic analysis of hydatidiform moles and point out its perspectives in the diagnostics of this disease.

Review.

Institute of Medical Biology, Genetics and Clinical Genetics, Faculty of Medicine, Comenius University in Bratislava, Slovak Republic.

Analysis of published literature data from the internet databases PubMed, ScienceDirect, Scopus and printed literature from the period 1963-2019.

This review refers on karyotyping, flow cytometry, FISH (Fluorescent in Situ Hybridization), VNTR-RFLP analysis (Variable Number of Tandem Repeats-Restriction Fragment Length Polymorphism), VNTR-PCR analysis (Variable Number of Tandem Repeats-Polymerase Chain Reaction) and STR (Short Tandem Repeat) genotyping of hydatidiform moles. The article summarizes possible application of these methods in the differential diagnostics of molar pregnancy (partial and complete hydatidiform moles) and nonmolar hydropic abortions.

Genetic analyses offer precise identification of types of molar pregnancies when histopathological diagnosis is not clear during early stages of pathology.

Genetic analyses offer precise identification of types of molar pregnancies when histopathological diagnosis is not clear during early stages of pathology.

An overview of urinary incontinence issues after vaginal delivery versus instrumental delivery.

A review article.

Compilation of published data from scientific literature.

Ústav pro studium odborných předmětů a praktických dovedností, Fakulta zdravotnických věd, Univerzita Palackého v Olomouci. EGFR inhibitor Centrum vědy a výzkumu, Fakulta zdravotnických věd, Univerzita Palackého vOlomouci.

Pregnancy and childbirth can lead to injuries of the pelvic floor muscles. The age of the firstborn in the pelvic floor disorders is similar to that of the end of pregnancy. Surgical vaginal delivery is an important part of modern obstetric practice. This serves to facilitate the delivery of the head. Includes vacuumextraction (VEX) and forceps. Forceps-assisted delivery has a lower failure rate than vacuum-assisted delivery but is associated with a higher incidence of maternal pelvic floor trauma.

Pregnancy and childbirth can lead to injuries of the pelvic floor muscles. The age of the firstborn in the pelvic floor disorders is similar to that of the end of pregnancy. Surgical vaginal delivery is an important part of modern obstetric practice. This serves to facilitate the delivery of the head. Includes vacuumextraction (VEX) and forceps. Forceps-assisted delivery has a lower failure rate than vacuum-assisted delivery but is associated with a higher incidence of maternal pelvic floor trauma.

To summarize current knowledge about the composition and function of the vernix caseoza with respect to the prenatal and postnatal period.

Summary article.

Department of Obstetrics and Gynecology, University Hospital Hradec Kralove.

According to current knowledge about composition, vernix caseoza consists of desquamate cells from outer layers of epidermidis with proteolipid material. The formation of vernix caseoza is related to the formation of the fetal skin. The lipid content protects a fetus from maceration with amniotic fluid. EGFR inhibitor Vernix caseoza further enhance the process of adaptation during the transition of a newborn from intrauterine to postnatal life. During delivery, vernix caseoza serves mainly as lubricant function. In a postpartum period, verxic caseoza may have moisturizing, antiinflammatory, antioxidative and healing function.

According to current knowledge about composition, vernix caseoza consists of desquamate cells from outer layers of epidermidis with proteolipid material. The formation of vernix caseoza is related to the formation of the fetal skin. The lipid content protects a fetus from maceration with amniotic fluid. link2 Vernix caseoza further enhance the process of adaptation during the transition of a newborn from intrauterine to postnatal life. During delivery, vernix caseoza serves mainly as lubricant function. In a postpartum period, verxic caseoza may have moisturizing, antiinflammatory, antioxidative and healing function.

Description of diagnosis of 45,X/46,XY ovotesticular DSD.

Case report.

Department of Medical Genetics, KZ a.s., Masaryk Hospital, Ústí nad Labem.

45,X/46,XY ovotesticular DSD is a diagnosis, which in this case was detected by chromosomal examination was performed, in which the child showed karyotype 45,X[2]/46,XY[8] - a pathological male karyotype correlated with the syndrome 45,X/46,XY ovotesticular DSD (disorder of sexual development). At the same time, a variant of chromosome 1045,X,inv(10) (p11q21.2)/46,XY,inv(10)(p11q21.2) was detected.

The phenotype of patients with mosaic karyotype 45,X/46,XY ranges in a wide range from the female phenotype with classical Turner syndrome, through individuals with ambiguous genitals to normal but infertile men. Thus, both Turners syndrome and virilization can be expected. link= EGFR inhibitor Gonads are usually dysgenetic with insufficiently differentiated testicular tissue, which can occur in both gonads (mixed gonadal dysgenesis) or only in one (asymmetric gonadal dysgenesis). With this type of gonadal dysgenesis, there is a risk of gonadoblastoma or other tumors.

The phenotype of patients with mosaic karyotype 45,X/46,XY ranges in a wide range from the female phenotype with classical Turner syndrome, through individuals with ambiguous genitals to normal but infertile men. Thus, both Turners syndrome and virilization can be expected. Gonads are usually dysgenetic with insufficiently differentiated testicular tissue, which can occur in both gonads (mixed gonadal dysgenesis) or only in one (asymmetric gonadal dysgenesis). With this type of gonadal dysgenesis, there is a risk of gonadoblastoma or other tumors.

An analysis of POVT (postpartum ovarian vein thrombosis) case, the importance of prompt diagnosis, antibiotic and anticoagulation therapy management with multidisciplinary team approach.

A case report and literature review.

1st Department of Gynaecology and Obstetrics, Faculty of Medicine Comenius University and University Hospital, Bratislava, Slovakia.

Authors would like to draw attention to the pitfalls of diagnosis and treatment of postpartum ovarian vein thrombosis with combination of antibiotics and anticoagulants after uncomplicated vaginal delivery.

Due to potentially life-threatening postpartum complications such as sepsis and pulmonary embolism, prompt diagnosis and treatment of POVT are important. link3 To detection of POVT are MRI and CECT associated with higher sensitivity and specificity compared to colour Doppler ultrasound. link2 For symptomatic POVT many authors suggest anticoagulation for 3 to 6 months (until there is radiologically confirmed thrombus resolution) with the addition of antibiotics for 7 to 10 days (in the case of suspected infection). Multidisciplinary approach is important.

Due to potentially life-threatening postpartum complications such as sepsis and pulmonary embolism, prompt diagnosis and treatment of POVT are important. To detection of POVT are MRI and CECT associated with higher sensitivity and specificity compared to colour Doppler ultrasound. For symptomatic POVT many authors suggest anticoagulation for 3 to 6 months (until there is radiologically confirmed thrombus resolution) with the addition of antibiotics for 7 to 10 days (in the case of suspected infection). Multidisciplinary approach is important.

Evaluation of the development of assisted reproduction methods and their success from the time of their origin to the present.

Review article.

Department of Obstetrics and Gynaecology, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague.

Literature search using the Web of Science, Google Scholar and PubMed databases with keywords (assisted reproduction, in vitro fertilization, infertility, ICSI, ovarian hyperstimulation syndrome, OHSS, uterine transplantation) and analysis of articles published in impact and reviewed journals.

At present children born using assisted reproduction methods are not considered as amiracle of modern medicine, but as a more difficult way of human reproduction. Reproductive medicine helps to fulfill the desires of infertile couples for their own child and thus improve the quality of their life. Since its introduction into clinical practice it has made extraordinary progress. Robert Edwards and Patrick Steptoe, thanks to systematic scientific the continuous improvement of medical technologies and scientific discoveries threatens to inadequate manipulation of human gametes or embryos. The society should monitor these controversial aspects through its legislative and control mechanisms and ensure that these methods are not misused for other than strictly medical purposes.

The main aim of organized national cervical cancer screening programs is to decrease incidence and mortality of this malignancy. A total of 770 cases of cervical cancer and 354 deaths from the disease were noticed in the Czech Republic in 2017 which means the incidence 14,5 new cases per 100 000 women. The Czech national cervical cancer screening program is based on cytology (Pap smear) testing in asymptomatic women once a year.

To provide an overview of new possibilities and potential tools in cervical cancer screening worldwide and in the Czech Republic.

Gynecologic Oncology Center, Department of Gynecology and Obstetrics, Hospital Na Bulovce and 1st Medical School of Charles University, Prague; Gynecologic Oncology Center, Department of Gynecology and Obstetrics, General Faculty Hospital and 1st Medical School of Charles University, Prague.

For this review, we have used the results of studies, review articles, and guidelines of national cervical cancer screening programs published in English. We sutrategy of cervical cancer screening are discussed.

The knowledge that persistent human papillomavirus (HPV) infection is the main cause of cervical cancer has resulted in the development of new possibilities of cervical cancer screening worldwide. HPV testing use for cervical cancer screening is now a reality with a quite lot of countries. Nevertheless, HPV testing is mainly used in the stratification of patients with unclear results of a cytological (PAP smear) result in the Czech Republic. While there is a wide and growing consensus that HPV molecular testing is the most accurate and cost-effective method of primary screening, there is a comparative lack of consensus regarding the optimal stratification of patients with proven HPV infections. link3 Biomarkers, such a p16/Ki67 dual immunostaining, a methylation of viral DNA, a detection of E6/E7 mRNA, and others have been proposed for triage of HPV positive women. New possibilities and approaches in strategy of cervical cancer screening are discussed.

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