Olssonrogers6342
05). After the nursing intervention, the intraocular pressure values (IOP), the visual field pattern standard deviations (PSD), the cup/disk area ratios (C/D AR), the mean retinal nerve fiber layer thicknesses (mRNFLT), and the other indexes in the comprehensive nursing group were significantly better than they were in the routine nursing group, and the comprehensive nursing group showed notably better quality of life and psychological states and a notably higher compliance rate than the routine nursing group (all P<0.05).
Targeted comprehensive nursing can help glaucoma patients correct bad behaviors, improve their compliance rates and quality of life, and alleviate their negative emotions.
Targeted comprehensive nursing can help glaucoma patients correct bad behaviors, improve their compliance rates and quality of life, and alleviate their negative emotions.
To study the efficacy of pirfenidone (PFD) on patients with pulmonary fibrosis caused by acute paraquat (PQ) poisoning.
A total of 86 patients with pulmonary fibrosis caused by acute PQ poisoning admitted to our hospital were analyzed retrospectively. All of them successfully received the standard 21-day treatment based on "Taishan Consensus", and they were assigned to the PFD group or the NO-PFD group according to whether they received PFD treatment (at 200 mg/time, 3 times/day) for 6 months after discharge. The two groups were compared in effective treatment rate, mortality and incidence of adverse reactions such as liver and kidney function damage, pulmonary fibrosis-associated indexes, pulmonary function-associated indexes, and arterial blood gas indexes before and after therapy.
The PFD group showed a notably higher effective treatment rate than the NO-PFD group (P<0.05). Additionally, the PFD group showed notably lower levels of serum hyaluronic acid (HA), laminin (LN), type IV collagen (CIV), and arterial blood gas status of patients, without causing obvious liver and kidney damage.To introduce a novel technique to reconstruct the acetabular labrum using capsular autograft, and to evaluate the preliminary clinical outcome, a retrospective review of a prospectively collected registry was undertaken that identified 21 patients (21 hips) who underwent arthroscopic reconstruction of the labrum by capsular autograft from January 2016 to January 2018. Modified Harris Hip Score (mHHS), Hip Outcome Score (HOS), and Hip Outcome Score-Activities of Daily Living (HOS-ADL) were recorded preoperatively and postoperatively. Clinical outcome was analyzed to evaluate the effectiveness of this technique. Twenty-one patients, with an average follow-up time of 25.4 ± 1.6 months, were included in this study 7 patients were diagnosed with hypoplastic labrum (width less then 5 mm), 9 patients with complex tear of labrum, and 5 patients with degenerative labrum. The mHHS (61.3 ± 5.5 vs. 87.5 ± 4.2, P less then 0.001), HOS (52.5 ± 5.1 vs. 87.3 ± 3.8, P less then 0.001) and HOS-ADL (48.5 ± 5.8% vs. 75.2 ± 3.5%, P less then 0.001) between preoperative and the 6-month follow-up were significantly different. 5-(N-Ethyl-N-isopropyl)-Amiloride research buy Gender exerts no influence on the outcome of mHHS, HOS and HOS-ADL. Therefore, local capsular autograft is readily available during arthroscopy with no donor-site morbidity. The reconstruction of the hip labrum may be valuable for patients with hypoplastic or dysplastic labrum, complex tear of labrum and severe degeneration. With appropriate patient selection, this technique is promising in preliminary clinical outcome.
To select and obtain the best evidence for parastomal hernia (PH) prevention in patients with enterostomy so as to provide reference for clinical practice to decrease the rate of PH.
Based on the method of evidence-based nursing, this paper proposes the prevention and management of PH in patients with enterostomy. link2 The literature was checked according to the "6S" model, and literature evaluation standards (2016 edition) of JBI Evidence-based Health Care Center in Australia were adopted to evaluate the literature quality and evidence level of various studies.
Combined with the judgment of professionals, 24 pieces of relevant evidence from 7 dimensions were summarized, including related controllable risk factors, diagnosis and identification, nutrition, the strength of abdominal wall muscle around the stoma, reduction of abdominal pressure, the use of belt on treatment of PH, and the prevention of complications related to PH.
This study summarized the best evidence of nonsurgical prevention and management of PH in patients with enterostomy, and provided an evidence-based basis for nurses to carry out clinical work, so as to use scientific methods to manage and prevent the occurrence of PH in patients with enterostomy and improve the quality of care.
This study summarized the best evidence of nonsurgical prevention and management of PH in patients with enterostomy, and provided an evidence-based basis for nurses to carry out clinical work, so as to use scientific methods to manage and prevent the occurrence of PH in patients with enterostomy and improve the quality of care.
To report a case of successful ovarian stimulation and pregnancy in an infertile woman with Rathke's cleft cyst (RCC).
This is a case report of a 32-year-old infertile woman with RCC presenting with secondary amenorrhea and hypogonadotropic hypogonadism (HH). Three rounds of ovarian stimulation and ovulation induction by means of HMG and HCG were performed (two before HSG and one after HSG). HSG was performed after two rounds of ovulation induction without pregnancy to assess the fallopian tubes and uterine cavity of the patient. Serum beta-human chorionic gonadotropin (β-HCG) and ultrasound examination were performed after the third round of ovulation induction to confirm successful pregnancy.
HSG revealed that the uterine cavity was normal and that the bilateral fallopian tubes were unobstructed. Four weeks after the third round of ovulation induction, the β-HCG test was positive (10261 μg/L), and ultrasound examination showed an intrauterine early gestational sac with an embryo (10*7 mm) and a primitive heart tube pulse.
Infertility accompanied by RCC is rare in the clinic. Clarifying the cause of infertility and secondary amenorrhea is very important for achieving a successful pregnancy. This case demonstrates that such infertility can be treated effectively with ovarian stimulation and ovulation induction using HMG and HCG. To the best of our knowledge, this is the first case report of infertility accompanied by RCC.
Infertility accompanied by RCC is rare in the clinic. Clarifying the cause of infertility and secondary amenorrhea is very important for achieving a successful pregnancy. This case demonstrates that such infertility can be treated effectively with ovarian stimulation and ovulation induction using HMG and HCG. To the best of our knowledge, this is the first case report of infertility accompanied by RCC.
This research is both a case study and a systematic literature review. Our goal was to learn more about the pathophysiology, clinical features, and therapy options for idiopathic mesenteric phlebosclerosis (IMP).
A case of IMP was treated by surgery in our department. Combined with the data of 240 cases of IMP retrieved from PubMed and Wanfang Data, we conducted a systematic review of this less well-known disease.
These 240 cases of IMP mainly occurred in East Asia. Among the patients, 78.7% of them had a history of herbal medicine consumption; 15.2% had no obvious symptoms and their diagnosis was confirmed through characteristic CT findings and colonoscopic manifestations; 58.4% were cured by conservative treatment; 41.6% had severe symptoms and underwent surgical treatment. Additionally, more patients treated with surgical treatment had lesions involving the cecum (59/82 vs. 53/115,
=0.0003) and sigmoid colon (20/82 vs. 10/115,
=0.0025) compared with those treated conservatively.
The occurrence of IMP is associated with the long-term consumption of herbal medicines. Early diagnosis of IMP could be determined by CT and colonoscopy and conservative or surgical treatment was chosen based on of the severity of the condition (e.g., the involved bowel segment).
The occurrence of IMP is associated with the long-term consumption of herbal medicines. Early diagnosis of IMP could be determined by CT and colonoscopy and conservative or surgical treatment was chosen based on of the severity of the condition (e.g., the involved bowel segment).The most common sites of breast cancer metastasis are the lymph nodes, lungs, bones, and liver. Gastrointestinal (GI) metastasis is relatively rare and often occurs within several years after a breast cancer diagnosis. Most patients experience abdominal pain, anorexia, bleeding, vomiting, and other digestive system symptoms, symptoms which are difficult to distinguish from primary gastric cancer. There is no characteristic change seen under a digestive tract endoscopy, and the difference in morphology under the pathological microscope from that of primary poorly differentiated gastric adenocarcinoma is so small that it can easily cause a misdiagnosis. This paper reports the case of 46-year-old female patient whose first symptom was GI discomfort. link3 She was hospitalized for GI surgery with an unknown medical history, but, during the preoperative examination, multiple breast masses were found on both sides, which were proved by pathology to be invasive lobular cancer. According to the medical literature, bilateral breast cancer with gastric metastasis is very rare, and, so far, this is the first reported case. Despite it being a rare phenomenon, it is necessary to be aware of the possibility of metastatic lobular carcinoma in the diagnosis of poorly differentiated gastric adenocarcinoma by biopsy.Previous research has shown that CCR10 acts as a vital oncogene in the progression of multiple malignancies. However, its effect on the treatment of non-small-cell lung cancer (NSCLC) has not been investigated. Current research examined the effect of CCR10 on the cellular survival and migration of NSCLC, and the modulation of cell death and found that the expression levels of CCR10 and CCL27 (ligand) were highly upregulated in human NSCLC tissue and cell lines, A549 and H157, compared with adjacent normal lung specimens. MTT and colony formation assays revealed that the blockage of CCR10 inhibited the multiplication and survival of A549 and H157 cells. Further study showed that metastasis-relevant VEGF-C/D, MMP-2/9, TIMP-1/2 were also regulated via CCR10 activation. Notably, increased NF-κB levels were detected in cells with activated CCR10, whereas the levels of NF-κB decreased in cells with blocked CCR10. Finally, the recovery of NF-κB expression counteracted the suppressive influence of CCR10 blockage on NSCLC cell survival, migration, and invasion. These results improved our knowledge understanding the molecular mechanisms of CCR10-CCL27 in progression of NSCLC.
To investigate the clinical effect of the four-step pouch plastic surgery in ocular plastic surgery.
Patients with ocular plastic surgery admitted to our hospital from January 2018 to October 2019 were selected as the study subjects. The patients were divided into the observation group (
=41) and the control group (
=43) according to the different surgical modalities received. The traditional skin approach of lower eyelid, and the four-step pouch plastic surgery were used as the control group and observation group, respectively. The operation time, postoperative recovery time of the eye skin, clinical effect, postoperative complications, and satisfaction rate were compared between the two groups.
The operation time was compared between the two groups, indicating no significant difference (
> 0.05). The postoperative recovery time of the eye skin was significantly shorter in the observation group than the control group (
< 0.05). The total clinical effective rate (95.12%) was significantly higher in the observation group than that in the control group (79.
