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A clear understanding of energy devices would help achieve high effectiveness and safety and guide the selection of devices. The present review aimed to elucidate the efficacy and adverse events of energy devices in lung cancer to guide the selection of appropriate devices depending on the situation.

Four major databases were searched electronically for relevant articles published until 16 April 2021. The reference lists of the identified papers were examined. We excluded (1) irrelevant studies, (2) manuscripts published in languages other than English and Japanese, (3) duplicates, and (4) studies for which the full text was not available in the databases. The results and key information obtained were summarized by means of a narrative approach.

A total of 78 papers were included in the review and these were categorized according to the main topic of investigation as follows (1) electrosurgery-related injuries, (2) fundamentals of electrosurgery, (3) monopolar devices, (4) bipolar electrosurgical devices, (5) ultrasonic energy devices, (6) energy devices in lung cancer surgery, (7) operating room fire risks, and (8) basic principles of surgery.

Understanding energy devices could help us use them in a more effective and safer manner. Knowledge of their selection criteria (suitability), merits, risks, and safety precautions relevant to each process of lung cancer surgery could guide appropriate selection.

Understanding energy devices could help us use them in a more effective and safer manner. Knowledge of their selection criteria (suitability), merits, risks, and safety precautions relevant to each process of lung cancer surgery could guide appropriate selection.

Acute kidney injury (AKI) is a major cause of mortality in tumor lysis syndrome. The biochemical parameters and kinetics of tumor lysis syndrome remain poorly described. Particularly, whether blood serum phosphate variations may help in the identification and management of patients who will eventually develop AKI remains to be studied.

In this retrospective study, we included patients with tumor lysis syndrome episodes without AKI at diagnosis, and analyzed serum phosphate kinetic, clinical and tumor lysis syndrome biochemical variables to identify factors associated with AKI onset, and determine threshold values of phosphatemia associated with AKI development.

One hundred thirty tumor lysis syndrome episodes occurred in 120 patients during an 11-year period at the University Hospital of Angers. AKI developed in 56 tumor lysis syndrome episodes. In multivariable analysis, among the analyzed factors, only an increase in serum phosphate levels (before AKI diagnosis), exposure to platinum salts and an incred studies on phosphate monitoring and phosphate lowering therapies to prevent AKI during tumor lysis syndrome.

Sand flies are the only proven vectors of leishmaniases, a tropical neglected disease endemic in at least 92 countries. Vector-parasite interactions play a significant role in vector-borne disease transmission. There are various bottlenecks to Leishmania colonization of the sand fly midgut. Such bottlenecks include the production of innate immune-related molecules, digestive proteases, parasite impermeable peritrophic membrane, and resident gut microbiota. These barriers determine the parasite load transmitted and, consequently, the disease outcome in mammalian host. Therefore, it is important to understand the molecular responses of both sand fly and Leishmania during infection.

Here, we reviewed the published literature on sand fly-Leishmania interactions bringing together earlier and current findings to highlight new developments and research gaps in the field.

Recent research studies on sand fly-Leishmania interaction have revealed contrasting observations to past studies. However, how Leishmania parasites evade the sand fly immune response still needs further research. Sand fly response to Leishmania infection can be best understood by analyzing its tissue transcriptome. Better characterization of the role of midgut components could be a game changer in development of transmission-blocking strategies for leishmaniasis.

Recent research studies on sand fly-Leishmania interaction have revealed contrasting observations to past studies. However, how Leishmania parasites evade the sand fly immune response still needs further research. Sand fly response to Leishmania infection can be best understood by analyzing its tissue transcriptome. Better characterization of the role of midgut components could be a game changer in development of transmission-blocking strategies for leishmaniasis.

In Saudi Arabia, records on molecular identification of tick-borne infections in camels are relatively scarce; few molecular epidemiological studies have been conducted.

This study aimed to find Anaplasma speciesand Piroplasma spp. in camels from Riyadh and the Eastern Region, Saudi Arabia.

A total of 1369 blood samples were collected from camels from Riyadh and the Eastern Region and analyzed for the DNA of Anaplasma and Piroplasma species by polymerase chain reaction (PCR).

Piroplasma spp. infection was not observed in any of the blood samples. 616 camels (44.99%) were found to be positive for Anaplasma infection by PCR targeting the 16S rRNA and COX1 genes. Six Anaplasma sequences for the 16S rRNA gene (OK481101-OK481106) were deposited in GenBank and six for the COX1 gene (OK490994-OK490999). They showed 98.3% and 62.7% similarities with Anaplasma marginale (A. marginale) detected in Kenya and Brazil, respectively. Phylogenetic studies revealed that the 12 sequences reported in this study were closely related; they were found in the same cluster as A. marginale isolates previously recorded in South Africa, Brazil, USA, China, and Israel.

Finally, 12 Anaplasma sequences closely related to A. marginale were detected in camels in Riyadh and the Eastern Region, Saudi Arabia. Camels in these areas were confirmed to be free of Piroplasma.

Finally, 12 Anaplasma sequences closely related to A. marginale were detected in camels in Riyadh and the Eastern Region, Saudi Arabia. Camels in these areas were confirmed to be free of Piroplasma.

There is an increase in the incidence of scabies in Turkey, which started before the Covid-19 pandemic, and this situation is considered as an epidemic. With this study, we aimed to reveal the prevalence of scabies during the pandemic period and the risk factors that are effective in the transmission of scabies.

Our study was performed as a cross-sectional study in 376 patients who applied to our dermatology outpatient clinic between 1st and 30th April 2021. Sociodemographic and socioeconomic characteristics, living space, health behavior, and health care utilization of the patients were questioned.

The prevalence of scabies was determined as 10.9%. Features such as sex, area of residence, age, formal education status, employment status, total income, number of shower, number of people per room, water source, and heating method, which were found to be significant as a result of the double test, were included in the logistic regression analysis. Scabies was found 2.728 times (CI 1.325-5.557) more in those who live in rural areas than those who live in urban areas, 2.714 times (CI 1.365-5.451) more in men than women, 2.707 times (CI 1.256-5.833) more in nonworking than working, 2.354 times (CI 1.057-5.243) more in those with less than 9 showers per month than those with 9 or more showers per month.

During the Covid-19 pandemic period, the prevalence of scabies in Turkey is increasing and it is becoming a serious health problem. Our study emphasizes this increase and determines the risk factors for transmission.

During the Covid-19 pandemic period, the prevalence of scabies in Turkey is increasing and it is becoming a serious health problem. Our study emphasizes this increase and determines the risk factors for transmission.The American Diabetes Association guidelines for the management of type 2 diabetes mellitus recommends treating patients with atherosclerotic cardiovascular diseases, heart failure or diabetic kidney disease with sodium-glucose co-transporter-2 inhibitors or glucagon-like peptide-1 receptor agonists, irrespective of the baseline HbA1c, to reduce adverse renal and cardiovascular outcomes. CompK mw Initiation of such therapies have a significant cost impact on health economies. Cost of gain in quality-adjusted life-years is normally used for cost effectiveness for a particular drug. In the absence of head-to-head comparisons, prescribers may go for the cheapest option, which may not necessarily be the right decision. We propose using the calculated 'YoDa' (Years of Drug administration) as an easily comparable metric between the drug accrual cost and clinical outcomes. YoDa is calculated as a product of numbers needed to treat and the median duration in years that the trial ran over, to accrue the positive clinical outcomes. Clinical phenotyping of the patient to the specific inclusion and exclusion criteria of relevant clinical trials could guide the clinician to choose the most appropriate therapy. We also propose a series of steps or 'deliberations', which a clinician should consider in making a final choice of sodium-glucose co-transporter-2 inhibitor therapy. A comprehensive summary of the sodium-glucose co-transporter-2 inhibitor trials, clinical phenotyping and YoDa calculations for various significant clinical outcomes could assist making evidence-based, patient-individualised and cost-effective management plans for diabetes care. Informing and Empowering Patients and Clinicians to Make Evidence-Supported Outcome-Based Decisions in Relation to SGLT2 Inhibitor Therapies The Use of The Novel Years of Drug administration (YoDa) Concept.

Ureteral complications are common in kidney transplanted patients; approximately 2.6-15% of patients develop ureteral obstruction/stenosis at some time after surgery, which is one of the most frequent urologic complications. Inguinal herniation of the neoureter is a rare complication but it must be taken into account.

We describe the case of a 78-years old male kidney transplanted patient (2004), who was admitted at the emergency room due to abdominal pain and with evidence of acute kidney injury. The ultrasound showed hydronephrosis (grade III) along with ureteral dilatation which ended with an image compatible with a kinking, that was confirmed at the TC and showed that the kneeling was in the right inguinal canal. It was possible, with a manual hernia reduction manoeuvre, to readjust the kneeling of the neoureter resolving the condition temporarily. The patient underwent underwent surgical hernia repair with no complication and complete recovery of renal function.

When ureter obstruction of the transplanted kidney occurs, it is crucial to resolve the obstruction as soon as possible in order to preserve kidney function. Hernioplastic is an effective way to treat ureter obstruction when it is caused by its herniation.

When ureter obstruction of the transplanted kidney occurs, it is crucial to resolve the obstruction as soon as possible in order to preserve kidney function. Hernioplastic is an effective way to treat ureter obstruction when it is caused by its herniation.