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This paper presents the design and the characterization of a portable laser triangulation measurement system for measuring gap and flush in the car body assembly process. Targeting Human in the Loop (HILT) operations in the manufacturing sector, and in line with the vision of human empowerment with Industry 4.0 technologies, the instrument embeds features to ease operators' activity and compensate possible misuse that could affect the robustness and the quality of data acquired. The device is based on a smartphone integrated with a miniaturized laser triangulation system installed in a cover. The device embodies additional sensors and control systems in order to guarantee operators' safety (switching on and off the laser line based on specific conditions), support operators during the measurement execution task, and optimize the image acquisition process for minimizing the uncertainty associated to the measurement. The smartphone performs on-board processing and allows Wi-Fi communication with the plant IT invironmental conditions) is larger than the instrument calibration uncertainty because the measurement process is affected by the operator and the variable conditions of the production line.Background Ostracism is a negative experience that has been studied primarily in laboratory settings. This study extends current research by investigating ostracism in daily life, analyzing the transition from social death to social resurrection of Catholic partners who suffered ostracism both in the couple (with the consequent divorce) and in the religious community they belong to (ban from religious practices). Therefore, we introduce the notion of 'cumulative ostracism'. Method Data are composed of the biographical narratives of n = 25 participants in a religious experience group in a period of 7 months. A narrative analysis was used within the framework of the temporal need-threat model. Results Participants' narratives are consistent with the temporal need-threat model. The ostracism experience, both in the couple and in the religious group, is characterized by the sequence immediate stage, coping stage and resignation stage. Moreover, the cumulative ostracism suffered by the participants presents an analogy with the cumulative trauma that occurs in intra-family abuse. Social resurrection occurs through the encounter with a new religious group that allows ostracized people to experience a Catholic religious affiliation again. Sunitinib Conclusions Our findings reflect the existing theory and add to the existing laboratory research by capturing ostracism-unique dynamics in real life.Periodic cleaning of all frequently touched social areas such as walls, doors, locks, handles, windows has become the first line of defense against all infectious diseases. Among those, cleaning of large wall areas manually is always tedious, time-consuming, and astounding task. Although numerous cleaning companies are interested in deploying robotic cleaning solutions, they are mostly not addressing wall cleaning. To this end, we are proposing a new vision-based wall following framework that acts as an add-on for any professional robotic platform to perform wall cleaning. The proposed framework uses Deep Learning (DL) framework to visually detect, classify, and segment the wall/floor surface and instructs the robot to wall follow to execute the cleaning task. Also, we summarized the system architecture of Toyota Human Support Robot (HSR), which has been used as our testing platform. We evaluated the performance of the proposed framework on HSR robot under various defined scenarios. Our experimental results indicate that the proposed framework could successfully classify and segment the wall/floor surface and also detect the obstacle on wall and floor with high detection accuracy and demonstrates a robust behavior of wall following.This article presents the development of a reversed-phase ultra-high-performance liquid chromatographic method for determining process-related impurities in ropinirole hydrochloride drug substance applying the analytical quality by design approach. The current pharmacopeial method suffers from selectivity issues due to two coelutions of two pairs of impurities. The development of a new method began with preliminary experiments, based on which the Acquity UPLC BEH C8 was selected as the most appropriate column. The effects of six different critical method parameters (CMPs) were then investigated using a fractional factorial screening design. Column temperature, the ratio of methanol in mobile phase B, and gradient slope turned out to be highly significant CMPs in achieving critical resolutions, and they were further evaluated using a central composite face-centered response-surface design. Mathematical models were created by applying a multiple linear regression method. Based on the elution order of an unknown degradation impurity and impurity C, two design spaces were established, and for each design space an optimal combination of CMPs was determined. The method developed was validated for precision, accuracy, linearity, and sensitivity, and it was proven suitable for determining nine process-related impurities of ropinirole.Contact with the natural environment in green and blue spaces can have a valuable influence on population physical and mental health and wellbeing. The aim of this study is to explore the economic evidence associated with the public's value for accessing, using and improving local environments to undertake recreational activity and consuming the associated health benefits of green and blue spaces. Applying the Preferred Reporting Items for Systemic Reviews and Meta-Analyses (PRISMA) guidelines, a systematic literature search was conducted. Peer-reviewed articles were sought using electronic databases, scrutiny of reference lists, experts and grey literature. All relevant papers meeting the criteria were critically appraised for methodological quality using the Drummond checklist. The review search concluded with 12 papers applying the Grades of Recommendation, Assessment, Development and Evaluation (GRADE) approach to assess the quality with a narrative analysis conducted under the themes. Results suggest the public value access to green and blue spaces to undertake recreational activities and avoid delay or losing the recreational experience and associated health benefits.

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