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Different models consider that the sleep state misperception could be correlated to structural abnormalities of the central nervous system. A recent study showed that the medial prefrontal cortex had a lower activation in patients with unrefreshing sleep due to chronic fatigue syndrome. This case report highlights the possibility of sleep state misperception having - at least partially - an anatomical substrate in the left nucleocapsular region.The current COVID-19 pandemic is a public health emergency that has seriously affected mental health in the general population. Both, studies on previous epidemics and those conducted during the current pandemic have reported a wide range of psychosocial consequences and multiple psychological symptoms as a result of said outbreaks, and among these problems, sleep/wake cycle alterations stand out. https://www.selleckchem.com/products/mevastatin.html Publications addressing this phenomenon have consistently reported that nearly a third of people who experience social isolation develop insomnia, which, in turn, is an important predictor for mental disorders that affect people's functionality, including anxiety disorders, depression and post-traumatic stress disorder. This reflection paper aims to describe the effects that social isolation may have on sleep in the context of the current COVID-19 pandemic.Patients with obstructive sleep apnea (OSA) may show signs and symptoms of altered swallowing function since repetitive episodes of OSA may cause hypoxia (decreased oxygen concentration in the blood) and hypercapnia (increased carbon dioxide concentration in the blood), as well as neuromuscular changes in the tissues involved, including the pharynx. This study aims to analyze whether patients with OSA show signs and symptoms of altered swallowing function. A literature search was performed in the PubMed, LILACS, Medline, Scopus, and SciELO databases by using the following search strategy ("dysphagia") or ("deglutition disorders") and ("obstructive sleep apnea") or ("obstructive sleep apnea syndrome"). The included articles were sorted by authors, year, country, journal of publication, and type of study, as well as analyzed according to the objectives, case series, OSA and swallowing assessment methods, results and conclusions. After applying the inclusion and exclusion criteria, ten articles published in medicine, dentistry and physiology journals between 1999 and 2018 were selected. The analysis of the selected articles showed that the number of participants and group structuring vary according to the study and instrumental and objective exams are used to assess swallowing and sleep in most articles. Also, the results show that groups of patients with OSA can present altered swallowing reflex, altered latency time and inspiratory suppression time, and presence of premature posterior escape, residues, penetration and aspiration. Premature posterior escape was the most frequent sign found. In conclusion, patients with OSA may show signs and symptoms of altered swallowing function.

Obesity or overweight are two factors associated with insulin resistance (IR). link2 There are limited studies with regard to the role of some non-traditional factors such as sleep quality in level of IR in obese individuals. The current study aimed at investigating the association of sleep quality with IR in overweight or obese people.

In this cross-sectional study, 612 obese or overweight participants of the Qazvin metabolic disease study (QMDS) were evaluated. Sleep quality was measured using the Pittsburgh sleep quality index (PSQI) and compared between two groups of participants with and without IR.

Our findings showed that the total score of sleep quality in the IR group was significantly lower than that in the non-insulin resistant group (8.78±2.78 vs. 8.13±2.70, p=0.008). After adjustment, each unit increase of the sleep latency and subjective sleep quality scores was associated with a 1.23 and 1.33 times increased risk of IR, respectively (p<0.05).

In the obese or overweight people, sleep quality is associated with IR.

In the obese or overweight people, sleep quality is associated with IR.

Fatigue is one of the most common and persistent complaints of pregnant women. Increased severity of fatigue during pregnancy can increase the risk of preterm labor, prolonged labor, cesarean section, and postpartum depression. Therefore, this study aimed to determine the fatigue status in different trimesters of pregnancy and its relationship with sleep quality in pregnant women.

This cross-sectional study was performed by two-stage cluster sampling on pregnant women referred to Tabriz health centers. Data were collected using socio-demographic questionnaire, multidimensional assessment of fatigue and Pittsburgh sleep quality index.

Among the 605 pregnant women studied, 94.2% of women suffered from fatigue during pregnancy. The mean (standard deviation) of fatigue score in the first, second and third trimesters of pregnancy was 23.53 (8.05), 25.78 (6.56) and 26.46 (6.72), respectively. There was also significant reverse correlation between total fatigue score with total sleep quality score (p=0.031) and with an increase in fatigue, sleep quality was reduced.

The findings of this study may be used to design interventional measures for fatigue and medical care to improve quality of sleep in pregnancy.

The findings of this study may be used to design interventional measures for fatigue and medical care to improve quality of sleep in pregnancy.

To investigate the prevalence of insomnia and its different phenotypes as well as their association with fear of COVID-19 in the general population.

This was a cross-sectional study conducted using an online survey (e-poll). All available participants who completed the online survey form were included in the current study. All individuals with a history of sleep problems were excluded. A questionnaire package consisted of insomnia severity index (ISI), and FCV-19 for corona fear was administered for all participants. Insomnia was defined as ISI≥8. Insomnia phenotypes were considered as (a) DIS difficulty initiating sleep; (b) DMS difficulty maintaining sleep; (c) EMA early morning awakening; and (d) combined insomnia.

A total of 1,223 participants [827 (67.6%) female, mean age=39.82±10.75 years old], enrolled in the current survey. Based on ISI, 675 (55.2% [95%CI=52.40-57.98]) were categorized into the insomnia group. Insomnia was more prevalent in females (p=0.006), participants with 50 years old or higher (p=0.04), or high fear of COVID-19 (p<0.0001). Totally, 67.4%, 66.4%, and 55% of all participants had DIS, DMS, and EMA, respectively, in the current outbreak. link3 Besides, 79% had impaired daily functioning, 51.6% had impaired quality of life, and 62% were worried about their sleep problem. Notably that a considerable percentage of individuals with normal ISI scores had at least one insomnia phenotype or impaired daily functioning and quality of life. Further analyses revealed a significant increasing trend in all four insomnia phenotypes prevalence with an increase in fear of COVID-19 (all p-values<0.0001).

Individuals with higher age, female gender, or higher fear of COVID-19 are at higher risk of all types of insomnia as well as impaired daytime performance or quality of life.

Individuals with higher age, female gender, or higher fear of COVID-19 are at higher risk of all types of insomnia as well as impaired daytime performance or quality of life.

In the COVID-19 pandemic, physical and psychological health are of immense concern for the governing bodies and health policymakers in the period of lockdown and self-isolation. An in-depth analysis is required to recognize the changes in mental health among the public of different geographical areas.

The study aimed to investigate the sleep quality and anxiety among the population in Saudi Arabia during the lockdown period from March to June 2020.

We conducted a cross-sectional study and surveyed the population in Saudi Arabia during the lockdown. We analyzed the anxiety and sleep quality in a population with variable socio-demographic profiles. We assessed anxiety using the self-rating anxiety scale (SAS) questionnaire and tested the sleep quality by using the Pittsburgh sleep quality index (PSQI) questionnaire. We analysed the questionnaire responses to determine the relationships between anxiety, stress, sleep disturbances by using SPSS, and considered the p-value<0.05 statistically significant.

l guidelines ought to be available for the public. Health measures through the promotion of lifestyle modifications, mindful body practices, meditation, and home exercise can reduce stress and improve the quality of sleep.Adolescence is a phase with physiological and behavioral changes. One of them occurs in the sleep-wake cycle pattern, manifested by a phase delay. However, morning school start time can decrease sleep duration during weekdays, impairing adolescent cognitive performance and well-being. Adolescents of different ages and educational level might suffer the impact of academic demand on sleep-wake cycle and cognition differently. Thus, the aim of this study is to compare the sleep habits and quality, sleepiness upon awakening and attention components among adolescents in the first years of high school and college. 71 adolescents participated in the study (45 girls and 26 boys), 44 enrolled in high school morning classes (G1 - 15.5±0.7 years), from a private school, and 27 college students enrolled in morning classes (G2 - 18.8±1.04 years), from biosciences courses from a public institution. The groups did not differ in bedtime, get up time, time in bed and sleep irregularity. However, both groups showed differences according to the day of the week, bedtime and get up time became later and time in bed extended on weekends. G1 presented worse sleep quality and regarding attention, showed higher percentage of omissions in all components and worse performance in sustained attention (ANOVA, p less then 0.05). The poorer sleep quality of high school adolescents and reduced attention may have a negative effect on school performance. Additional studies are needed to investigate the causes of these differences between these two educational levels.

The effects of high-intensity interval training (HIIT) combined with resistance training (RT) in adults with obesity and sleep-related breathing disorders (SRBDs) is limited.

This study aimed to examine the effects of HIIT combined with RT on subjective sleep disorders in adults with obesity and SRBDs.

This study was a pre- and post-test design. Seventeen adults with obesity and SRBDs were recruited into the study. They received 24 minutes of HIIT and 30 minutes of RT, 3 times/week for 6 weeks. The Epworth sleepiness scale (daytime sleepiness), Berlin questionnaire (snoring and daytime sleepiness category), estimated maximum oxygen consumption (VO

max), muscle strength using 1-repetition maximum, anthropometric variables, and blood biomarkers were examined at baseline and after 6 weeks of training.

The Epworth sleepiness scale, Berlin questionnaire (daytime sleepiness category), and the number of risks associated with sleep apnea using the Berlin questionnaire were significantly decreased after 6 weeks of training (all p<0.