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To date, cinnamon supplementation has been investigated due to its antioxidant and anti-inflammatory properties. Several studies have confirmed the effects of cinnamon supplementation on several markers of cardiometabolic health. However, the effects of cinnamon supplementation on inflammation and oxidative stress levels warrant further investigation. Hence, the current meta-analysis was conducted to elucidate the impact of cinnamon supplementation on biomarkers of inflammation and oxidative stress.

To perform this systematic review and meta-analysis, we employed the Preferred Reporting Items of Systematic Reviews and Meta-Analysis (PRISMA) guidelines. The systematic search of available clinical trials was performed using the following databases PubMed/MEDLINE, Scopus, Cochrane Library, Web of Science, Embase, and Google Scholar, up to January 2020.

After removing the duplicates, 1145 studies were eligible for analysis and 12 of them were included in the meta-analysis. The dose of cinnamon powder investigated in the included trials ranged from 1.5 to 4 g/day. Cinnamon supplementation resulted in a significant reduction of C-reactive protein (CRP) (weight mean difference (WMD) -2.22 mg/L, 95 % CI -3.74, -0.69, P = 0.004) and malondialdehyde (MDA) (WMD -0.79 mmol/L, 95 % CI -1.28, -0.29, P = 0.002), and marginally statistical significant decrease in interleukin-6 (IL-6) (WMD -1.48 pg/mL, 95 % CI -2.96, -0.01, P = 0.049). Moreover, it was associated with an increase in the total antioxidant capacity (TAC) (WMD 0.34 mmol/L, 95 % CI 0.04, 0.64, P = 0.026). However, the levels of intercellular adhesion molecule-1 (ICAM-1) (WMD 1.53 ng/mL, 95 % CI -12.03, 15.10, P = 0.82) did not change significantly following cinnamon supplementation.

Cinnamon supplementation may be an adjuvant for reducing inflammation and oxidative stress levels in humans.

Cinnamon supplementation may be an adjuvant for reducing inflammation and oxidative stress levels in humans.

The purpose of this systematic review is to evaluate the effect nature exposure has on stress as measured by physiologic markers and self-report.

Researchers searched PubMed and JSTOR. Randomized control trials and cross-sectional studies were included if they met the following criteria 1) included a clinical cohort and controls, and the intervention was nature exposure, either real or simulated; (2) utilized measurements of sympathetic activity or perceived stress; (3) study population consisted of greater than thirty male and female volunteers. Twelve studies were included for data extraction and review.

Researchers conducted this review at University of South Florida Morsani College of Medicine.

Researchers measured perceived stress through the Perceived Stress Scale (PSS) and Depression, Anxiety, and Stress Scale (DASS). Physiologic stress was measured by salivary cortisol, blood pressure (BP), subgenual prefrontal cortex (sgPFC) activation on functional magnetic resonance imaging (fMRI), skin conductance level (SCL), heart rate variability (HRV), muscle tension, heart period, pulse transit time, amygdala and pregenual anterior cingulate cortex (pACC) activation on fMRI, respiratory sinus arrhythmia (RSA), and pre-ejection period (PEP).

This review found an inverse relationship between nature exposure and various physiologic markers of stress in all 7 studies measuring physiologic stress. Perceived stress was also affected by higher exposure to nature as indicated by lower self-reports on the PSS and DASS in 5 out of 6 studies measuring perceived stress.

Nature exposure has been widely shown to have a positive effect in reducing stress, both perceived and physiologic.

Nature exposure has been widely shown to have a positive effect in reducing stress, both perceived and physiologic.

Attention-deficit/hyperactivity disorder (ADHD) is a significant neurobehavioral disorder in children and adolescence which may be affected by diet.

To evaluate the possible relationship between sugar consumption and the development of symptoms of ADHD.

In March 2020, an exhaustive systematic literature search was conducted using Google Scholar, PubMed, and Scopus. compound 78c cost In this meta-analysis of observational studies, odds ratios, relative risks, hazard ratios, and their 95% confidence intervals, which was reported for ADHD regarding SSBS, soft drink consumption, and dietary sugars, were used to calculate ORs and standard errors. At first, a fixed-effects model was used to drive the overall effect sizes using log ORs and SEs. If there was any significant between-studies heterogeneity, the random-effects model was conducted. Cochran's Q test and I

were used to measure potential sources of heterogeneity across studies. The Newcastle-Ottawa scale was used to assess the quality of the included articles.

Seven studies, two cross-sectional, two case-control, and three prospective with a total of 25,945 individuals were eligible to include in the current meta-analysis. link2 The association between sugar and soft drink consumption and the risk of ADHD symptoms were provided based on the random-effects model (pooled effect size 1.22, 95%CI 1.04-1.42, P = 0.01) (I² = 81.9%, P

< 0.0001).

This meta-analysis indicated a positive relationship between overall sugar and sugar-sweetened beverages consumption and symptoms of ADHD; however, there was heterogeneity among included studies. Future well-designed studies that can account for confounds are necessary to confirm the effect of sugar on ADHD.

This meta-analysis indicated a positive relationship between overall sugar and sugar-sweetened beverages consumption and symptoms of ADHD; however, there was heterogeneity among included studies. link3 Future well-designed studies that can account for confounds are necessary to confirm the effect of sugar on ADHD.

Some studies have investigated the effect of Lavender on pain and the healing of wounds. The aim of this systematic review was to investigate the effect of Lavender on pain and wound healing of episiotomy.

The Cochrane Library, MEDLINE (PubMed), Scopus, and Web of Science (all databases from inception until February 2020) were searched. Data were extracted from eligible studies by two review authors individually. Our inclusion criteria were full-text interventional studies published in English or any other languages. All data were analyzed using Review Manager 5.3. The protocol of this systematic review was registered in PROSPERO with the reference number CRD42020140623.

Our search found six trials involving 415 participants. The use of Lavender could significantly reduce pain in women with episiotomy (95 % CI -1.06 - -0.32). The use of Lavender has significantly improved the healing of episiotomy compared to the placebo (95 % CI -2.13 - -1.34). In all studies, pain and healing of episiotomy were evaluaer may be considered for wound healing of episiotomy.

The objective of meta-analysis of randomized controlled trials (RCTs) was to evaluate the effects of probiotic supplementation on metabolic status in patients with neurological disorders.

The following databases were search up to April 2019 Pubmed, Scopus, Google scholar, Web of Science, and Cochrane Central Register of Controlled Trials. The quality of the relevant extracted data was assessed according to the Cochrane risk of bias tool. Data were pooled by the use of the inverse variance method and expressed as mean difference with 95 % Confidence Intervals (95 % CI).

Nine studies were included in this meta-analysis. The findings suggested that probiotic supplementation resulted in a significant reduction in C-reactive protein (CRP) [Weighted Mean Difference (WMD) -1.06; 95 % CI -1.80, -0.32] and malondialdehyde (MDA) levels (WMD -0.32; 95 % CI -0.46, -0.18). Supplementation with probiotics also significantly reduced insulin (WMD -3.02; 95 % CI -3.88, -2.15) and homeostatic model assessment for insulin resistance (HOMA-IR) (WMD -0.71; 95 % CI -0.89, -0.52). Probiotics significantly reduced triglycerides (WMD -18.38; 95 % CI -25.50, -11.26) and VLDL-cholesterol (WMD -3.16; 95 % CI -4.53, -1.79), while they increased HDL-cholesterol levels (WMD 1.52; 95 % CI 0.29, 2.75).

This meta-analysis demonstrated that taking probiotic by patients with neurological disorders had beneficial effects on CRP, MDA, insulin, HOMA-IR, triglycerides, VLDL-cholesterol and HDL-cholesterol levels, but did not affect other metabolic parameters.

This meta-analysis demonstrated that taking probiotic by patients with neurological disorders had beneficial effects on CRP, MDA, insulin, HOMA-IR, triglycerides, VLDL-cholesterol and HDL-cholesterol levels, but did not affect other metabolic parameters.Metabolic acidosis, which can be affected by dietary acid-base load, seems to be associated with psychological disorders through different pathways. Given limited evidence on dietary acid-base load, we aimed to examine the association of dietary acid-base load with psychological disorders in Iranian women. This cross-sectional study was performed on 447 female subjects (20-50 years old). Dietary intake was assessed using a valid food frequency questionnaire for Iran. Dietary acid-base load was calculated through different indices including potential renal acid load (PRAL), net endogenous acid production (NEAP), and dietary acid load (DAL). To assess psychological disorders, an Iranian validated version of depression, anxiety, and stress scale (DASS-21) was used. The mean value of PRAL, NEAP, and DAL were -8.87mEq/da, 37.94mEq/day, and 30.77mEq/day, respectively. Considering a wide range of confounding variables, compared with the first tertile, a significant positive association was observed between dietary acid-base load and depression (ORPRAL 3.63; 95 %CI1.97, 6.71; Ptrend = 0.0001) (ORNEAP3.42; 95 %CI 1.87, 6.23; Ptrend = 0.0001) (ORDAL 3.02; 95 %CI 1.64, 5.58; Ptrend = 0.0001). Women in the high dietary acid-base load category had higher anxiety (ORPRAL 3.31; 95 %CI 1.81, 6.06; Ptrend = 0.0001) (ORNEAP3.47; 95 %CI 1.90, 6.33; Ptrend = 0.0001) (ORDAL 3.25; 95 %CI 1.76, 5.98; Ptrend = 0.0001). Moreover, there was a strong positive relationship between dietary acid-base load and psychologicaldistress (ORPRAL 3.79; 95 %CI 2.09, 6.90; Ptrend = 0.0001) (ORNEAP 3.67; 95 %CI 2.04, 6.58; Ptrend = 0.0001) (ORDAL 3.00; 95 %CI 1.66, 5.43; Ptrend = 0.0001). Women with higher dietary acid-base load score had greater odds for depression, anxiety, and psychological distress compared to lower ones.

The primary aim of this study was to evaluate differences in the prevalence of complementary and alternative medicine (CAM) usage among children with and without developmental disabilities (DD). Secondarily, the association between CAM usage and comorbid chronic medical conditions was explored among children with DD.

Data come from the 2012 Child Complementary and Alternative Medicine Supplement of the National Health Interview Survey, a nationally representative sample of children in the United States between the ages of 4 and 17 (n = 10,218).Main outcome measures Multiple logistical regression models provided insight into the relationships between parent-report CAM usage, DD, and chronic medical conditions.

Children with developmental disabilities were more likely to use CAMs compared to their typically developing peers (21% vs 16%). Children with DDs and comorbid chronic medical conditions used CAMs at even higher rates (23% vs 18%).

Results indicated that children with DD, especially those with a co-occurring chronic medical condition, use CAMs more often that typically developing children.