Mygindiversen2009

A cooperative metal-ligand (Cu2+ and enamide ligand) interaction is proposed based on the characterization of ligated Cu(ii) intermediates with the techniques of X-ray crystallography, UV-vis spectroscopy, cyclic voltammogram, EPR spectroscopy, and DFT calculations.L. plantarum LP3 isolated from traditinal fermented Tibetan yak milk has been identified as a potential probiotic candidate strain with high cholesterol-lowering activity. In this study, thirty Sprague-Dawley (SD) rats were randomly divided into three groups, including normal diet (NC), high-fat diet (HC), and high-fat diet + L. plantarum LP3 (HLp). The effects of L. plantarum LP3 on plasma lipid profile, gut bacterial microbiota, and metabolome induced by high-fat diet in rats were investigated. Results shown that L. plantarum LP3 administration was found to reduce the levels of total cholesterol, triglyceride, and low-density lipoprotein cholesterol (LDL-C) and atherogenic index in the serum of high-fat diet rats. It also controlled the decrease of Bacteroidetes and increase of Firmicutes at the phylum level in gut microbiota induced by high-fat diet in SD rats and increased the diversity and relative abundance of intestinal flora in obese rats. In particular, the LP3 strain controlled the changes induced by the high-fat diet in the abundance of for Lachnospiraceae and Erysipelotrichaceae. We also further observed the beneficial regulatory effects of L. plantarum LP3 on changes in the levels of obesity-related metabolites. The biosynthesis of fatty acids, steroids, and bile acids and metabolism of linoleic acid, linolenic acid, and arachidonic acid were the main metabolic pathways adjusted by L. plantarum LP3 in obese rats, and the metabolic rates were similar to those observed in normal diet rats levels. The findings of this study provided useful information on the mechanism underlying the hypocholesterolemic effects of L. plantarum LP3 in the high-fat induced SD rat model with the perspective of modulation of gut microbiota and metabolites.A new borate fluoride, Li3CaB2O5F, has been synthesized. It features a sandwich-like structure with the adjacent [Li3OF]∞ and [CaO]∞ layers connected by the weak Li-O bonds and the [B2O5] dimers. Interestingly, Li3CaB2O5F has large ionic conductivity, which is attributed to the diverse and wide Li-ion diffusion pathways.A triangular Er3 cluster containing polyoxometalate (POM), [Er3(μ3-OH)(H2O)8(AsW9O33)(AsW10O35(dl-mal))]222- (1) (mal = malate), has been obtained via one-pot reactions. Structural analyses demonstrate that three Er3+ ions bridged one μ3-OH to generate a rare μ3-OH-capped triangular Er3 cluster, which connects two different vacant polyanions to form an unsymmetrical sandwich-type subunit, and adjacent sandwiched subunits are linked through mal ligands to give the targeted dimer. When the Er3+ ions are substituted in whole or in part with Y3+ ions, the diamagnetic yttrium analogue [Y3(μ3-OH)(H2O)8(AsW9O33)(AsW10O35(dl-mal))]222- (2) and diluted sample [Er0.15Y2.85(μ3-OH)(H2O)8(AsW9O33)(AsW10O35(dl-mal))]222- (Er@2) have also been synthesized. Magnetic studies reveal that 1 exhibits field-induced two-step magnetic relaxation processes; the slow relaxation process may arise from intramolecular magnetic interactions, whereas the fast one is likely to originate from the intermolecular dipole-dipole interactions supported by the magnetic results of Er@2. From ab initio calculations, it is found that although the magnetic anisotropies of 1 mainly originate from individual Er3+ fragments, the Er3+-Er3+ interactions have a considerable influence on their slow magnetic relaxation processes.The excellent water solubility of hydrazine (N2H4) allows it to easily invade the human body through the skin and respiratory tract, thereby damaging human organs and the central nervous system. To realize the monitoring of N2H4 effectively, first, coumarin was used to construct an inner alicyclic ring as the reaction site, extending the conjugation and strengthening the rigidity of the probe Co-Hy to improve its luminescence performance and enhance its ability to resist acids and alkalis. Second, we introduced a carboxyl group at the ortho position of the inner alicyclic ring to improve the water solubility of Co-Hy, and its strong electron pulling effect increased the activity of the reaction site. Spectroscopy experiments showed that Co-Hy featured excellent water solubility, high pH resistance (pH 4-11), excellent selectivity, fast analysis speed (within 5 minutes), and a low detection limit toward N2H4 (69 nM, 2.2 ppb). In addition, test-strip, spray, and cell-imaging experiments confirmed the outstanding application potential of Co-Hy for convenient N2H4 analysis in a variety of environments.A single thiocatecholate group has been combined with a phthalocyanine and used to coordinate a [Ni(dppe)]2+ fragment to give the unprecedented title complex [(dppe)Ni(S2PcH2)]. Oligomycin A concentration UV-Vis spectroscopy shows new strong transitions in the Q-band, which TDDFT calcualtions predict result from internal charge transfer processes. Insights are gained with respect to designing future photocatalytic systems.A rhodium-catalyzed diastereo- and enantio-selective cyclopropanation of α-boryl styrenes with α-diazoarylacetates was established. Rh2(S-PTTL)4 (0.2 mol%) was found to be effective for the conversion, and 21 diastereopure cyclopropylboronates were prepared in high yields with excellent enantioselectivity (ee up to 99%).Nano-ESI is a commonly used ionization technique with continually expanding analytical advantages. Here, we report a facile way for high-frequency (500-3800 Hz) pulsing of nano-ESI, providing a high flux of mobility-selected ions. The pulsing is accomplished using a relatively low-voltage modulation (80 V peak-to-peak) of an electrode placed 50% of those in continuous nano-ESI without ion selection, underscoring efficient ion generation via high-frequency pulsing. These findings indicate the potential of the pulsed nano-ESI for enhanced analytical utility, such as a high-flux selected-reagent-ion supplier at atmospheric pressure, and chart new avenues to further enhance the analytical performance of nano-ESI.