Moserkloster1703

993). The DrugLog© method had good linearity and precision, offering an automated determination of bilirubin and oxyhemoglobin, eliminating operator bias.

The DrugLog© instrument has a short assay time and showed good agreement with traditional spectrophotometry.

The DrugLog© instrument has a short assay time and showed good agreement with traditional spectrophotometry.

Screening for latent tuberculosis infection (LTBI) using interferon gamma release assays has become commonplace for a variety of reasons. Given the high test volume, automated platforms are highly desired.

To this end, we performed an operational usability study using a newly FDA-approved, fully automated, random-access platform.

Our results showed that this platform can save time and labor and will be a potential useful addition to streamline LTBI screening. Studies to verify performance characteristics are warranted.

Our results showed that this platform can save time and labor and will be a potential useful addition to streamline LTBI screening. Studies to verify performance characteristics are warranted.The article continues the cycle of scientific research devoted to the reconstruction of the tragic events of Russian history by the methods of forensic medical examination. The archival data of the criminal case on the murder in Kiev in 1911 of the Prime Minister of Russia P.A. Stolypin has been published in the scientific literature first time. Formulation a forensic diagnosis and reconstruction of the posture of the victim were done based on comparison of the data from the inspection of the scene, the characteristics of the firearms and the results of the examination of the body. The obtained data arguably disprove the positions of the victim and the killer, which are generally accepted in journalism and artworks.The criminal prosecution of medical workers for harm to the health of patients is currently one of the actively developed areas of work of the Investigative Committee. Investigators have a very vague idea about the peculiarities of the objects of evidence in this category of cases, which leads to an abundance of issues in the ruling, the resolution of which often does not allow achieving the goal of the investigation. This leads the issuance of new decisions and producing of many additional and repeated examinations. The passive position of the experts does not improve the situation either. The methodology for investigating cases of harm to the patient's health by a doctor during the production of forensic medical examinations in criminal proceedings requires an expert to actively participate in establishing the circumstances to be proved. This methodology is proposed at the training cycle of the Department of Forensic Medicine of the Military Medical Academy named after V.I. C.M. Kirov. STM2457 The article provides a previously unpublished generalized scheme of the algorithm that can be used in the production of forensic medical examinations in this category of cases.

Is to draw the attention of forensic experts and histologists to the problem of infectious diseases occurring with the formation of granulomas. Was reviewed the general patterns of granulomatous diseases, as well as the peculiarities of pathomorphosis in helminthiasis (schistosomiasis, paragonimiasis, onchocerciasis, dirofilariasis, ascariasis, cysticercosis), mycoses (cryptococcosis, chromomycosis, coccidioidosis) and protozoal diseases, toxosomes. The article includes photomicrographs from the authors' personal archive, including those collected during their work in African countries Text is based on scientific data from articles, monographs, educational literature, personal experience and cases of forensic medical practice.

Is to draw the attention of forensic experts and histologists to the problem of infectious diseases occurring with the formation of granulomas. Was reviewed the general patterns of granulomatous diseases, as well as the peculiarities of pathomorphosis in helminthiasis (schistosomiasis, paragonimiasis, onchocerciasis, dirofilariasis, ascariasis, cysticercosis), mycoses (cryptococcosis, chromomycosis, coccidioidosis) and protozoal diseases, toxosomes. The article includes photomicrographs from the authors' personal archive, including those collected during their work in African countries Text is based on scientific data from articles, monographs, educational literature, personal experience and cases of forensic medical practice.Based on the analysis of literature data, demonstrated the relevance of further research to establish the prescription of death, including in a hot arid zone. Taking into account the climate of the seasons of Uzbekistan was stressed the importance of a comprehensive assessment of the dynamics of the development of cadaveric changes and supravital reactions, together with the results of biochemical, morphological and morphometric studies of the brain, other organs and tissues at different times of the postmortem period in certain groups. It could be used to develop additional criteria for establishing the onset of death in a hot arid zone.

Is to develop a method for determining amlodipine in the tissues of organs and blood, applicable in the practice of forensic chemical analysis. TLC, normal pressure column chromatography, HPLC and GC-MS were considered as methods of analysis. Amlodipine was isolated from the biomaterial by insisting twice with acetone for 30 min using a 2 1 mass-isolating and biomatrix agent. The purification of recovered analyte was done in a column (150×10 mm) of a 30 µm Silasorb S-18 sorbent, eluting with an acetone - water solvent mixture (82). Preliminary identification was carried out in a thin layer of sorbent on «Sorbfil» plates, which was confirmed by HPLC and GC-MS methods. Determination by GC-MS was carried out in a column with a stationary phase of 5% phenyl-95% dimethylpolysiloxane. The fragmentation of molecules was an electron impact with an energy of 70 eV. Methods for the determination of amlodipine using GC-MS in biomatrix have been developed, which meet the criteria of linearity, selectivity, correctness, precision and stability.