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The patients with manifestations of osteochondrosis in the lumbar (65.2%) and cervical (50.8%) parts of the spine are predominated. Among all the syndromes, the pain syndrome was the leading one and was detected in 96.4% of patients. The frequency of disorders of various parts of the spinal column depended on working conditions. Thus, intellectual workers suffered more often from osteochondrosis of the cervical spine, and manual workers - from the lumbar spine. It is necessary to optimize primary and secondary prevention of osteochondrosis, taking into account the age and nature of the patients' labor activity as well as to improve medical care and the rational employment of people suffering from this disease.In Russia, in the conditions of ongoing demographic crisis and socioeconomic transformations, the reproduction of population, including indigenous minorities, is the urgent problem. The analysis of dynamics of the age structure and reproductive parameters of women of three generations was carried out in order to determine the characteristics of reproduction of the Shors, the indigenous minority of the Kemerovo Region. The statistical data of population censuses (1970-2015), questionnaire materials, records of household books were used as sources of information. The average indices of the main parameters of reproduction of the Shors were calculated and their comparative analysis was carried out. Pexidartinib manufacturer The analysis of the reproductive characteristics of Shor women the average age of the onset of menopause and menarche (climacterium is from 46.9±1.95 to 46.5±0.70 years, menarche from 14.5±0.65 to 13.9±0, 21 years old, p>0,05), the duration of the physiological reproductive period and the age of the woman at birth of tcture.The article devoted to consideration of ethnic feature of primary choice of subjects of health preservation by residents of the Republic of Khakassia. It is established that at equal consumption of medical care in out-patient and polyclinic organizations, among the ethnic population of there is higher demand of services of traditional healers, especially representatives of shaman practices. The primary effecting on decision making in choosing health care institutions is provided by folk customs and family traditions received from senior relatives that is especially expressed among the Khakass ethnos.The article presents characteristics of the factors affecting the quality of life of individuals with amputations of upper and lower limbs. The sources of the study were data of Rosstat, publications of Russian and foreign authors, the Federal Law "On social protection of disabled people in the Russian Federation", the UN Convention on the rights of disabled people and the State program of the Russian Federation "Accessible environment". On the basis of study results the actual characteristic of factors of quality of life of disabled amputees in the Russian Federation was presented.The article presents the results of analysis of primary and secondary disability due to malignant neoplasms among young people in Moscow in 2016-2018. The study established that in the structure of young patients recognized as disabled for the first time made up the smallest percentage with tendency of increasing the level of primary disability. The study established the predominance of people with disabilities of group II with high level of primary disability. The second position is taken by patients with disabilities of group III with tendency of increasing their specific severity. The number of patients repeatedly recognized as disabled is much higher than patients recognized as disabled for with the first time. The study established prevalence of disabled patients of group III with tendency of increasing level of repeated disability.Over the past 10 years in the Russian Federation, the health of citizens has been steadily deteriorating the level of natural population decline is increasing, and life expectancy is decreasing. When analyzing the causes of mortality according to the Federal State Statistics Service, it was revealed that most cases are noncommunicable diseases, their determinants are biological, the state of the environment, medical care, conditions and lifestyle of people. The aim of the study is to identify the degree of commitment of the population of the city of Vladivostok to a healthy lifestyle. A socio-hygienic study was carried out, which included a mass survey of residents of Vladivostok by random sampling. Issues related to the impact of conditions and lifestyles on public health have been studied. Results Analysis of the research data showed that 19% of men and 6% of women (p less then 0.05) lacked interest in life. A study of the data showed that currently 66% of women and 44% of men use tobacco products (p less then 0.05), 53% of women and 59% of men use alcohol (p less then 0.05), which are factors risk of noncommunicable socially significant diseases. The motivation for maintaining a healthy lifestyle of the population can be strengthened through systematic preventive measures to promote and maintain health.The article considers the results of continuous retrospective documentary study of regional characteristics of road traffic injuries with medical consequences on the Federal highway M-8 "Kholmogory" in the Arkhangelsk oblast in 2012 - 2018. The analysis was applied to 906 medical records of patients older than 18years hospitalized with urgent indications after road traffic accident and received in-patient treatment in medical organizations of the Arkhangelsk Oblast located in area of the Federal highway M-8 "Kholmogory". The significant decreasing of number of accidents with medical consequences recorded in the covered area as well as significant decreasing number of victims and perished with minimal rate ​​in 2018 was established. It is revealed that the largest number of victims of road traffic accidents was recorded in summer - 300 (31.1%) and autumn - 270 (29.8%) of this year. The Saturday and Sunday occurred to be the most dangerous days of the week in this respect. In day periodicity, maximal number of victims was recorded in the evening time (18-24 PM, 35.