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e Authors. Scandinavian Journal of Caring Sciences published by John Wiley & Sons Ltd on behalf of Nordic College of Caring Science.OBJECTIVES This study investigated morphological variations of lamina papyracea, the structure that should be carefully considered when opening posterior ethmoid sinus during endoscopic sinus surgery, to avoid injury. STUDY DESIGN This study employed axial, coronal, and sagittal computed tomography. METHODS Using computed tomography images of 228 face-sides, various anatomical parameters were determined distances of the anterior and posterior ethmoid arteries from the skull base, and from the third lamella; changes in the angles of the lamina papyracea at the anterior and posterior ethmoid sinuses; and presence or absence of supraorbital ethmoid cell (SECs), Onodi cell, and Haller cell. The relationship between the distances which indicate the point of maximum projection by the lamina papyracea among third lamina and posterior ethmoid artery into the posterior ethmoid sinus and these anatomical factors were analyzed statistically. RESULTS The projection distance of lamina papyracea into the posterior ethmoid sinus was -2.6 mm to 3.4 mm, and in 41.2% of cases, projection in the direction of the nasal cavity was greater than that of the lamina papyracea at the anterior ethmoid sinus. This distance increased with increasing distance of the maximum projection point from the skull base and increasing floating distances of the anterior and posterior ethmoid arteries. The number of subjects with large projection distances was increased among those with floating posterior ethmoid arteries. In addition, subjects with SECs had significantly greater projection distances. CONCLUSIONS Particular care should be taken to avoid injury to the lamina papyracea when opening the posterior ethmoid sinus in subjects with floating anterior or posterior ethmoid arteries, and/or SEC. LEVEL OF EVIDENCE 4 Laryngoscope, 2020. © 2020 The American Laryngological, Rhinological and Otological Society, Inc.KEY POINTS When exercise was prescribed to elicit a fixed evaporative heat balance requirement (Ereq), no differences in steady-state sweat rates were observed with different absolute esophageal and/or skin temperatures, secondary to differences in time of the day (i.e. AM vs. PM) and ambient temperature (i.e. 23°C vs. 33°C). Exercise at a fixed metabolic heat production (Hprod), but a different Ereq (due to differences in air temperature), yielded higher steady-state sweat rates with a higher Ereq, irrespective of absolute esophageal temperature. Circadian rhythm did not alter the change in core temperature prior to the onset for sudomotor activation, nor the thermosensitivity, resulting in similar cumulative whole-body sweat rates irrespective of time of day at a fixed Ereq. Collectively, these data indicate that during exercise in a compensable environment, steady-state sudomotor responses are influenced by Ereq rather than absolute core and skin temperatures, or Hprod. ABSTRACT The present study sought to-2 , (33°C, P = 0.001). However steady-state mean LSR (200 W·m-2 /23°C P = 0.25; 200 W·m-2 /33°C P = 0.86; 275 W·m-2 /33°C P = 0.53) and WBSR (200 W·m-2 /23°C P = 0.79; 200 W·m-2 /33°C P = 0.48; 275 W·m-2 /33°C P = 0.32) were similar. When Ereq was matched (200 W·m-2 ) with different Ta (23°C vs. 33°C), steady-state LSR (P > 0.17) and WBSR (P > 0.93) were similar despite different skin temperatures. For the same Hprod (525 W) but different Ereq (200 vs. 275 W·m-2 ), mean LSR (P  less then  0.001), and WBSR (P  less then  0.001) were higher with a greater Ereq . Vitamin A acid manufacturer Collectively, steady-state sweating during exercise is altered by Ereq but not Tes , skin temperature, or Hprod . This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.BACKGROUND Myofascial pain in masticatory muscles is one of the most common temporomandibular disorder. Nowadays, the most usable treatment methods are based on the muscle taut band cell membrane disruption, which releases the taut band. Platelet-rich plasma, made with PRGF Endoret® method, gives an opportunity to use platelet-derived growth factors in treatment processes. It has been proven that platelet-derived growth factors can relief pain and activate muscle regeneration. OBJECTIVE To test a hypothesis that PRGF injections can be effective for treating myofascial pain in masticatory muscles. METHODS Fifty adult patients participated in the study. Participants were randomly divided into two groups. The first group received 1-mL lidocaine injections to trigger point in their masseter muscle. The second group of patients received 1-mL PRGF injections. The patients' pain was measured by using visual analogue scale (VAS). RESULT Statistically significant difference in pain levels before the procedure and 4 weeks after it was found in both groups. There was no statistically significant difference between groups in pain levels before the procedure (P = .063) and 2 weeks after it (P = .123); however, statistically significant difference was noticed 4 weeks after the procedure (P  less then  .001). Four weeks after the procedure, patients' average pain in lidocaine group was 3.4 on VAS, and it was 0.9 in PRGF group. CONCLUSIONS PRGF injections in masseter muscle affected by myofascial pain syndrome are an effective treatment method. PRGF injections more effectively relief myofascial pain in masseter muscle than lidocaine injections. © 2020 John Wiley & Sons Ltd.This study aimed to search whether there is a link between reflux flow and hormonal profile. Data of 250 patients were retrospectively investigated. Pre-operative and 6th month semen analyses of these patients' results were compared with pre-operative and post-operative 6th month serum levels of testosterone. Based on the venous flow on pre-operative Doppler ultrasonography, patients were divided into two groups. Patients with a venous flow ≤4 s were assigned to Group 1 and those with a venous flow >4 s to Group 2. Venous reflux time cut-off was calculated as 4 s using ROC curve according to the increase in testosterone level. When venous reflux time was selected as approximately 4.0 s, ROC had 79.8% sensitivity and 72.8 specificity. The probability of a post-operative increase in testosterone is high in patients with a venous reflux time longer than 4 s. © 2020 Blackwell Verlag GmbH.At April 2020, this review has been withdrawn. It is correct at the date of publication, and previous versions can be accessed in the 'Other versions' tab on the Cochrane Library. We are aware of new studies to potentially change the conclusions, however the update did not meet the timelines and expectations of Cochrane and the PaPaS review group. Copyright © 2020 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.in English, French Childhood medulloblastoma is a case of childhood brain tumor that requires high attention due to a low survival rate. Effective prognosis depends a lot on accurate detection of its subtype. The present study proposes a texture-based computer-aided categorization of childhood medulloblastoma samples. According to the World Health Organization (W.H.O), it has four subtypes (desmoplastic, classic, nodular, and large). Classification is done in two levels i) normal and abnormal ii) its four subtypes. link2 The system is evaluated on indigenous patient samples collected from the region. The main objective of database generation is to create a dataset of childhood medulloblastoma samples since there exists no available benchmark dataset. The proposed framework is a model for the automatic classification of the samples. The tissue samples obtained post-operation by doctors are converted into images, and then necessary algorithms are applied so that certain features describing each group of the image are known and studied for classification. Later these images are classified using the image features into the subtypes of abnormal samples.The outbreak of Sars-CoV-2 (COVID-19) poses serious challenges to people's health worldwide. The management of the disease is mostly supportive, and respiratory failure from acute respiratory distress syndrome is the leading cause of death in a significant proportion of affected patients. Preliminary data point out that dramatic increase in IL-6 and subsequent cytokine release syndrome may account for the development of fatal interstitial pneumonia. Inhibition of IL-6 by blocking its specific receptor with monoclonal antibodies has been advocated as a promising attempt. Here we assess the potential utility of myo-Inositol, a polyol already in use for treating the newborn Respiratory Distress Syndrome, in downregulating the inflammatory response upon Sars-CoV-2 infection. Myo-Inositol proved to reduce IL-6 levels in a number of conditions and to mitigate the inflammatory cascade, while being devoid of any significant side effects. It is tempting to speculate that inositol could be beneficial in managing the most dreadful effects of Sars-CoV-2 infection.The COVID-19 (Coronavirus disease 2019) spreads primarily through droplets of saliva or discharge from the nose. link3 COVID-19 is predominantly considered as an unavoidable pandemic, and scientists are very curious about how to provide the best protection to the public before a vaccine can be made available. There is an urge to manufacture a greater number of masks to prevent any aerosol with microbes. Hence, we aim to develop an efficient viral inactivation system by exploiting active compounds from naturally occurring medicinal plants and infusing them into nanofiber-based respiratory masks. Our strategy is to develop fibrous filtration with three-layered masks using the compounds from medicinal plants for viral deactivation. These masks will be beneficial not just to healthcare workers but common citizens as well. In the absence of vaccination, productive masks can be worn to prevent transmission of airborne pathogenic aerosols and control diseases.OBJECTIVE On December 8, 2019, many cases of pneumonia with unknown etiology were first reported in Wuhan, China, subsequently identified as a novel coronavirus infection aroused worldwide concern. As the outbreak is ongoing, more and more researchers focused interest on the COVID-19. Therefore, we retrospectively analyzed the publications about COVID-19 to summarize the research hotspots and make a review, to provide reference for researchers in the world. MATERIALS AND METHODS We conducted a search in PubMed using the keywords "COVID-19" from inception to March 1, 2020. Identified and analyzed the data included title, corresponding author, language, publication time, publication type, research focus. RESULTS 183 publications published from 2020 January 14 to 2020 February 29 were included in the study. The first corresponding authors of the publications were from 20 different countries. Among them, 78 (42.6%) from the hospital, 64 (35%) from the university and 39 (21.3%) from the research institution. All the publications were published in 80 different journals. Journal of Medical Virology published most of them (n=25). 60 (32.8%) were original research, 29 (15.8%) were review, 20 (10.9%) were short communications. 68 (37.2%) epidemiology, 49 (26.8%) virology and 26 (14.2%) clinical features. CONCLUSIONS According to our review, China has provided a large number of research data for various research fields, during the outbreak of COVID-19. Most of the findings play an important role in preventing and controlling the epidemic around the world. With research on the COVID-19 still booming, new vaccine and effective medicine for COVID-19 will be expected to come out in the near future with the joint efforts of researchers worldwide.